تقرير
Autoimmune pulmonary alveolar proteinosis prior to myelodysplastic syndrome.
| العنوان: | Autoimmune pulmonary alveolar proteinosis prior to myelodysplastic syndrome. |
|---|---|
| المؤلفون: | Foo CT; Eastern Health Melbourne VIC Australia., Chhor L; Eastern Health Melbourne VIC Australia., Thien F; Eastern Health Melbourne VIC Australia.; Eastern Health Clinical School Monash University Melbourne VIC Australia. |
| المصدر: | Respirology case reports [Respirol Case Rep] 2020 May 05; Vol. 8 (5), pp. e00569. Date of Electronic Publication: 2020 May 05 (Print Publication: 2020). |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101631052 Publication Model: eCollection Cited Medium: Print ISSN: 2051-3380 (Print) Linking ISSN: 20513380 NLM ISO Abbreviation: Respirol Case Rep Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [Malden, MA] : John Wiley & Sons, Inc., [2013]- |
| مستخلص: | We report the first case of autoimmune pulmonary alveolar proteinosis (PAP) associated with and preceding myelodysplastic syndrome. A 74-year-old female with a history of polymyalgia rheumatica presented with six months history of progressive exertional breathlessness. Examination revealed bilateral chest crackles and exertional desaturation. A diagnosis of autoimmune PAP was made based on the presence of autoantibodies to granulocyte-macrophage colony-stimulating factor and characteristic findings on chest computed tomography, bronchoalveolar lavage, and transbronchial biopsies. Bilateral whole lung lavage was performed with prompt improvement in symptoms. Fourteen months later, she presented with new breathlessness and was diagnosed with myelodysplasia on bone marrow biopsy. No recurrence of alveolar proteinosis was detected. This case highlights the importance of follow-up and screening of patients with autoimmune PAP for haematological conditions. (© 2020 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology.) |
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| فهرسة مساهمة: | Keywords: Autoimmune; myelodysplastic syndrome; pulmonary alveolar proteinosis |
| تواريخ الأحداث: | Date Created: 20200508 Latest Revision: 20240328 |
| رمز التحديث: | 20240329 |
| مُعرف محوري في PubMed: | PMC7200416 |
| DOI: | 10.1002/rcr2.569 |
| PMID: | 32377347 |
| قاعدة البيانات: | MEDLINE |
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