دورية أكاديمية
Effective on-line high-speed shear dispersing emulsifier technique coupled with high-performance countercurrent chromatography method for simultaneous extraction and isolation of carotenoids from Lycium barbarum L. fruits.
| العنوان: | Effective on-line high-speed shear dispersing emulsifier technique coupled with high-performance countercurrent chromatography method for simultaneous extraction and isolation of carotenoids from Lycium barbarum L. fruits. |
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| المؤلفون: | Gong Y; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou, P. R. China.; University, of Chinese Academy of Sciences, Beijing, P. R. China., Huang XY; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou, P. R. China., Liu JF; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou, P. R. China.; University, of Chinese Academy of Sciences, Beijing, P. R. China., Pei D; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou, P. R. China.; Center of Resource Chemical and New Material, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Qingdao, P. R. China., Duan WD; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou, P. R. China.; University, of Chinese Academy of Sciences, Beijing, P. R. China., Zhang X; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou, P. R. China.; University, of Chinese Academy of Sciences, Beijing, P. R. China., Sun X; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou, P. R. China.; University, of Chinese Academy of Sciences, Beijing, P. R. China., Di DL; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou, P. R. China. |
| المصدر: | Journal of separation science [J Sep Sci] 2020 Jul; Vol. 43 (14), pp. 2949-2958. Date of Electronic Publication: 2020 Jun 08. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101088554 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1615-9314 (Electronic) Linking ISSN: 16159306 NLM ISO Abbreviation: J Sep Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Weinheim, Germany : Wiley-VCH, c2001- |
| مواضيع طبية MeSH: | Carotenoids/*isolation & purification , Lycium/*chemistry, Carotenoids/chemistry ; Chromatography, High Pressure Liquid ; Countercurrent Distribution ; Magnetic Resonance Spectroscopy ; Mass Spectrometry |
| مستخلص: | An efficient combination strategy based on high-speed shear dispersing emulsifier technique and high-performance countercurrent chromatography was developed for on-line extraction and isolation of carotenoids from the fruits of Lycium barbarum. In this work, the high-speed shear dispersing emulsifier technique has been employed to extract crude extracts using the upper phase of high-performance countercurrent chromatography solvent system composed of n-hexane-dichloromethane-acetonitrile (10:4:6.5, v/v) as the extraction solvent. At the separation stage, the high-performance counter-current chromatography process adopts elution-extrusion mode and the upper phase of the solvent system as stationary phase (reverse-phase mode). As a result, three compounds including zeaxanthin, zeaxanthin monopalmitate, and zeaxanthin dipalmitate with purities of 89, 90, and 93% were successfully obtained in one extraction-separation operation within 120 min. The targeted compounds were analyzed and identified by high-performance liquid chromatography, mass spectrometry, and NMR spectroscopy. The results indicated that the present on-line combination method could serve as a simple, rapid, and effective way to achieve weak polar and unstable compounds from natural products. (© 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.) |
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| معلومات مُعتمدة: | 2018ZX09711001-001-002 Drug Innovation Major Project; 2019BEF02006 Key Research and Development Program of Ninxia Hui Autonomous Region; 2016369 Youth Innovation Promotion Association CAS |
| فهرسة مساهمة: | Keywords: Lycium barbarum; high-performance countercurrent chromatography; high-speed shear technique; on-line combination |
| المشرفين على المادة: | 36-88-4 (Carotenoids) |
| تواريخ الأحداث: | Date Created: 20200509 Date Completed: 20210824 Latest Revision: 20210824 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1002/jssc.202000215 |
| PMID: | 32384220 |
| قاعدة البيانات: | MEDLINE |
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