دورية أكاديمية
A new triterpenoid saponin with nine sugar units from Anemone amurensis (Korsh.) Kom.
| العنوان: | A new triterpenoid saponin with nine sugar units from Anemone amurensis (Korsh.) Kom. |
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| المؤلفون: | Lv CN; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China., Zhao Y; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China., Lu JC; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China. |
| المصدر: | Natural product research [Nat Prod Res] 2021 Dec; Vol. 35 (23), pp. 5030-5035. Date of Electronic Publication: 2020 May 14. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Milton Park, UK : Taylor & Francis Health Sciences, c2003- |
| مواضيع طبية MeSH: | Anemone* , Antineoplastic Agents, Phytogenic* , Oleanolic Acid* , Saponins*/pharmacology , Triterpenes*/pharmacology, Drug Screening Assays, Antitumor ; Molecular Structure ; Sugars |
| مستخلص: | A new triterpenoid saponin named Anemonside A (1) was isolated from the rhizome of Anemone amurensis (Korsh.) Kom. Its structure was determined by chemical and spectral analysis, including 1D, 2D NMR data, HRESIMS and hydrolysis reaction. The new saponin contains nine sugar units with two O-linked sugar chains, which is relatively rare in natural products. In addition, the cytotoxic activity of Anemonside A was evaluated by against A549 and HepG2 cell lines with the MTT method and showed no cytotoxic activity with IC50 over 100 μM. |
| فهرسة مساهمة: | Keywords: Anemone amurensis (Korsh.) Kom; cytotoxic activity; triterpenoid saponin |
| المشرفين على المادة: | 0 (Antineoplastic Agents, Phytogenic) 0 (Saponins) 0 (Sugars) 0 (Triterpenes) 6SMK8R7TGJ (Oleanolic Acid) |
| تواريخ الأحداث: | Date Created: 20200516 Date Completed: 20211203 Latest Revision: 20211214 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1080/14786419.2020.1765344 |
| PMID: | 32408838 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1478-6427 |
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| DOI: | 10.1080/14786419.2020.1765344 |