دورية أكاديمية

INDOLENT, NONPROGRESSIVE, MULTIFOCAL CHOROIDAL LESIONS: A Presumed Benign Choroidal Lymphoid Disease.

التفاصيل البيبلوغرافية
العنوان: INDOLENT, NONPROGRESSIVE, MULTIFOCAL CHOROIDAL LESIONS: A Presumed Benign Choroidal Lymphoid Disease.
المؤلفون: Carroll WJ; Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Deak G; Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.; Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria., J Daily M; Wheaton Eye Clinic, Wheaton, Illinois., Cunha de Souza E; Hospital das Clínicas da FMUSP Department of Ophthalmology São Paulo, Brazil., Shelsta HN; Department of Ophthalmology, Virginia Commonwealth University, Richmond, Virginia; and.; Ophthalmology Outpatient and Surgical Services, Hunter Holmes McGuire VA Medical Center, Richmond, Virginia., Barbante Casella AM; Department of Ophthalmology, Hospital Universitário da Universidade Estadual de Londrina, Londrina, Brazil., Jampol LM; Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
المصدر: Retina (Philadelphia, Pa.) [Retina] 2020 Oct; Vol. 40 (10), pp. 1980-1987.
نوع المنشور: Case Reports; Journal Article
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8309919 Publication Model: Print Cited Medium: Internet ISSN: 1539-2864 (Electronic) Linking ISSN: 0275004X NLM ISO Abbreviation: Retina Subsets: MEDLINE
أسماء مطبوعة: Publication: Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: Philadelphia : Lippincott, [1981?-
مواضيع طبية MeSH: Choroid Neoplasms/*pathology , Intraocular Lymphoma/*pathology, Adult ; Aged ; Coloring Agents/administration & dosage ; Female ; Fluorescein Angiography ; Follow-Up Studies ; Humans ; Indocyanine Green/administration & dosage ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Multimodal Imaging ; Retrospective Studies ; Tomography, X-Ray Computed
مستخلص: Purpose: In 2012, four patients with multiple asymptomatic, indolent, unilateral, choroidal lesions were described. We suspected benign-behaving lymphocytes infiltrating the choroid. This article expands the number of patients and duration of follow-up and speculates further on the etiology. Although histopathologic confirmation of these lesions is still unknown, the natural course of these patients is excellent and should be distinguished from aggressive choroidal lymphoma.
Methods: To qualify for the study, the patients had to meet the following criteria: 1) Patients collected had asymptomatic choroidal infiltrates as demonstrated in the figures; 2) absence of vitreous cells; 3) no evidence of concomitant systemic malignancy; 4) no systemic inflammatory diseases, including sarcoidosis; 5) no birdshot chorioretinopathy; 6) no conjunctival or orbital lesions; and 7) advanced multimodal imaging and clinical follow-up were performed.
Results: There were 11 eyes of 11 patients seen. Follow-up ranged from 4 months to 12 years and 1 month (mean 50.2 months; median 24 months). Systemic workup was unrevealing. No patients in this cohort developed systemic, conjunctival, orbital, or vitreoretinal lymphoma or inflammatory disease. No patients developed symptoms or vision loss.
Conclusion: This entity is an indolent choroidal infiltrative disease. It resembles some cases of choroidal lymphoma and may represent an indolent lymphocytic infiltrate.
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المشرفين على المادة: 0 (Coloring Agents)
IX6J1063HV (Indocyanine Green)
تواريخ الأحداث: Date Created: 20200530 Date Completed: 20210910 Latest Revision: 20210910
رمز التحديث: 20240829
DOI: 10.1097/IAE.0000000000002865
PMID: 32467483
قاعدة البيانات: MEDLINE
الوصف
تدمد:1539-2864
DOI:10.1097/IAE.0000000000002865