دورية أكاديمية
Investigation of the changing etiology and risk factors of prosthetic joint infections : a university hospital surveillance study from 2011-2017.
| العنوان: | Investigation of the changing etiology and risk factors of prosthetic joint infections : a university hospital surveillance study from 2011-2017. |
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| المؤلفون: | Okay G, Bolukcu S, Durdu B, Gultepe BS, Tuncay İ, Koc MM |
| المصدر: | Acta orthopaedica Belgica [Acta Orthop Belg] 2020 Mar; Vol. 86 (1), pp. 54-63. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Acta Medica Belgica Country of Publication: Belgium NLM ID: 2985165R Publication Model: Print Cited Medium: Internet ISSN: 0001-6462 (Print) Linking ISSN: 00016462 NLM ISO Abbreviation: Acta Orthop Belg Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Bruxelles : Acta Medica Belgica Original Publication: Bruxelles. |
| مواضيع طبية MeSH: | Bacterial Infections/*epidemiology , Prosthesis-Related Infections/*epidemiology , Prosthesis-Related Infections/*microbiology, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Coinfection/epidemiology ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; Turkey/epidemiology ; Young Adult |
| مستخلص: | We sought to characterize the causative pathogens of prosthetic joint infections (PJIs), evaluate the trends in microbial etiologies, and identify potential risk factors for PJI. This was a retrospective study analyzing 70 patients with PJI following 3,253 total joint arthroplasties between 2011 and 2017. Staphylococci were the most common cause of infection (52.9%). There was a significant trend in the percentage of carbapenem-resistant gram-negative bacilli (GNB) (increased to 66.7% in 2016 from 0.0% in 2011) (p=0.021). GNB and polymicrobial etiology were found at significantly high levels in cases involving early PJIs (p=0.005 and p=0.048, respectively). While staphylococci were significantly higher in PJIs after total knee arthroplasty (75%), GNB were significantly higher in PJIs after total hip arthroplasty (49.1%) (p<0.001 and p=0.001, respectively). Binary logistic regression analysis showed that the risk of PJI was significantly higher in cases with fracture and diabetes mellitus (odds ratio [OR], 4.3, 95% confidence interval [CI], 1.78-10.5 ; OR, 4.1, 95% CI, 1.66-10.5, respectively). These results suggest that the empirical and targeted antimicrobial treatment of PJIs may become more difficult in the future. |
| تواريخ الأحداث: | Date Created: 20200604 Date Completed: 20201110 Latest Revision: 20201110 |
| رمز التحديث: | 20221213 |
| PMID: | 32490774 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0001-6462 |
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