دورية أكاديمية
Plummer-Vinson syndrome: A decade's experience of 132 cases from a single center.
| العنوان: | Plummer-Vinson syndrome: A decade's experience of 132 cases from a single center. |
|---|---|
| المؤلفون: | Patil M; Department of Gastroenterology, St. John's Medical College Hospital, Bangalore, India., Malipatel R; Department of Pathology, St. John's Medical College Hospital, Bangalore, India., Devarbhavi H; Department of Gastroenterology, St. John's Medical College Hospital, Bangalore, India. |
| المصدر: | Journal of gastroenterology and hepatology [J Gastroenterol Hepatol] 2021 Jan; Vol. 36 (1), pp. 181-185. Date of Electronic Publication: 2020 Jun 29. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Blackwell Scientific Publications Country of Publication: Australia NLM ID: 8607909 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1440-1746 (Electronic) Linking ISSN: 08159319 NLM ISO Abbreviation: J Gastroenterol Hepatol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Melbourne ; Boston : Blackwell Scientific Publications, c1986- |
| مواضيع طبية MeSH: | Plummer-Vinson Syndrome*/complications , Plummer-Vinson Syndrome*/therapy, Adolescent ; Adult ; Aged ; Anemia, Iron-Deficiency/etiology ; Deglutition Disorders/etiology ; Deglutition Disorders/surgery ; Dilatation and Curettage/methods ; Female ; Follow-Up Studies ; Gastrointestinal Neoplasms/epidemiology ; Gastrointestinal Neoplasms/etiology ; Humans ; Male ; Middle Aged ; Risk ; Time Factors ; Treatment Outcome ; Young Adult |
| مستخلص: | Background and Aim: Plummer-Vinson syndrome (PVS) comprises triad of iron deficiency anemia, dysphagia, and post-cricoid esophageal web. PVS is rare nowadays due to improved nutritional status. However, we encountered patients with PVS regularly at our center. Data regarding PVS are limited; hence, we aimed to study the clinical features, treatment outcomes, and development of complications in patients with PVS. Methods: The study was conducted over a 10-year period (January 2008 to January 2018) in a medical college setting. All adults with dysphagia, anemia, and post-cricoid web or those with iron deficiency anemia and post-cricoids web were included in the study. Patients were treated with iron supplementation and Savary-Gilliard bougie dilation of the web. Patients were followed-up for the recurrence of dysphagia and development of complications. Results: Overall, 153 patients exhibited esophageal web, of which 132 (86.27%) patients had concomitant PVS and 21 (13.7%) patients did not. The mean age was 43.50 years (range 16-76) and 113 (85.6%) were women. Single session of Savary-Gilliard bougie dilation was successful in 90.7% of patients in relieving dysphagia and 9.3% developed recurrence, requiring repeated dilations. Four patients had concomitant squamous cell carcinoma of esophagus along with PVS and two developed upper gastrointestinal malignancy during follow-up. Conclusion: Plummer-Vinson syndrome is predominantly seen in middle aged women and present with symptoms of iron deficiency anemia and early grade dysphagia. Single session of Savary-Gilliard bougie dilation was successful in majority of patients in relieving dysphagia. Overall risk of developing upper gastrointestinal malignancy was 4.5%. (© 2020 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.) |
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| فهرسة مساهمة: | Keywords: Plummer-Vinson syndrome (PVS); dysphagia; iron deficiency anemia; post-cricoid web |
| تواريخ الأحداث: | Date Created: 20200612 Date Completed: 20210705 Latest Revision: 20210705 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1111/jgh.15139 |
| PMID: | 32525241 |
| قاعدة البيانات: | MEDLINE |
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