دورية أكاديمية
أعرض في EDS

Relationship between penile erection and the ratio of estradiol to testosterone: A retrospective study.

التفاصيل البيبلوغرافية
العنوان: Relationship between penile erection and the ratio of estradiol to testosterone: A retrospective study.
المؤلفون: Pan D; Department of Urology, Shandong Provincial Hospital, Shandong, China.; Department of Urology, The Second Hospital of Shandong University, Jinan, China., Xu ZH; Department of Urology, The Second Hospital of Shandong University, Jinan, China., Gao Q; Department of General Surgery, Taishan Medical University, Taian, China., Li M; Department of Urology, Shandong Provincial Hospital, Shandong, China., Guan Y; Department of Urology, Shandong Provincial Hospital, Shandong, China., Zhao ST; Department of Urology, Shandong Provincial Hospital, Shandong, China.
المصدر: Andrologia [Andrologia] 2020 Oct; Vol. 52 (9), pp. e13701. Date of Electronic Publication: 2020 Jun 15.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Blackwell Pub Country of Publication: Germany NLM ID: 0423506 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-0272 (Electronic) Linking ISSN: 03034569 NLM ISO Abbreviation: Andrologia Subsets: MEDLINE
أسماء مطبوعة: Publication: : Berlin : Blackwell Pub.
Original Publication: Berlin, Grosse
مواضيع طبية MeSH: Erectile Dysfunction* , Penile Erection*, Estradiol ; Humans ; Male ; Penis ; Retrospective Studies ; Testosterone
مستخلص: Previous studies have found that the ratio of estradiol to testosterone (E2/T ratio) has a negative effect on sexual function, but the relationship between the E2/T ratio and erection of the penis is not clarified. We conducted a retrospective study of 183 patients with erectile dysfunction and 52 healthy men to investigate the relationship between penis base erection and tip erection. All participants underwent nocturnal penile tumescence tests and medical history checks and had relevant biochemical and endocrine indicators measured. The ratio of estradiol to testosterone was calculated. The relationship between E2/T ratio and erectile time of penile tip and penile base was determined by univariate analysis, multivariate analysis and stratification analysis. After adjusting for mixed factors, the results showed that the E2/T ratio had a more significant negative effect on the base of the penis compared with the tip of the penis (Hazard ratio: -4.34 95% CI: -6.52, -2.16 p = .0001). Moreover, when the effective erection time was ≥10 min, the negative effect of E2/T on penile root erection was more obvious (HR ratio: -4.46 95% CI: -6.50, -2.43 p < .0001). In summary, our study demonstrated a negative relationship between E2/T ratio and penile erection, particularly at the root of the penis.
(© 2020 Blackwell Verlag GmbH.)
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معلومات مُعتمدة: 81900613 National Nature Science Foundation of China; 81670625 National Nature Science Foundation of China; 81970578 National Nature Science Foundation of China; ZR2018BH007 Shandong Province Natural Science Foundation; 2019GSF108116 Shandong Province Natural Science Foundation
فهرسة مساهمة: Keywords: Rigiscan; erectile dysfunction; penile base; penile tip; the ratio of estradiol to testosterone
المشرفين على المادة: 3XMK78S47O (Testosterone)
4TI98Z838E (Estradiol)
تواريخ الأحداث: Date Created: 20200616 Date Completed: 20210621 Latest Revision: 20210621
رمز التحديث: 20231215
DOI: 10.1111/and.13701
PMID: 32539180
قاعدة البيانات: MEDLINE
الوصف
تدمد:1439-0272
DOI:10.1111/and.13701