دورية أكاديمية
Critical evaluation of different available guidelines for late-onset hypogonadism.
العنوان: | Critical evaluation of different available guidelines for late-onset hypogonadism. |
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المؤلفون: | Giagulli VA; Interdisciplinary Department of Medicine-Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari 'Aldo Moro', Bari, Italy.; Outpatients Clinic of Endocrinology and Metabolic Disease, Conversano Hospital, Bari, Italy., Castellana M; National Institute of Gastroenterology 'Saverio de Bellis', Research Hospital, Bari, Italy., Lisco G; Hospital Unit of Endocrinology, Perrino Hospital, Brindisi, Italy., Triggiani V; Interdisciplinary Department of Medicine-Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari 'Aldo Moro', Bari, Italy. |
المصدر: | Andrology [Andrology] 2020 Nov; Vol. 8 (6), pp. 1628-1641. Date of Electronic Publication: 2020 Jul 12. |
نوع المنشور: | Journal Article; Review |
اللغة: | English |
بيانات الدورية: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101585129 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-2927 (Electronic) Linking ISSN: 20472919 NLM ISO Abbreviation: Andrology Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Oxford : Wiley-Blackwell, 2013- |
مواضيع طبية MeSH: | Endocrinology/*standards , Eunuchism/*drug therapy , Hormone Replacement Therapy/*standards , Practice Guidelines as Topic/*standards , Testosterone/*therapeutic use, Adult ; Age of Onset ; Aged ; Biomarkers/blood ; Consensus ; Eunuchism/blood ; Eunuchism/diagnosis ; Eunuchism/physiopathology ; Evidence-Based Medicine/standards ; Hormone Replacement Therapy/adverse effects ; Humans ; Middle Aged ; Risk Factors ; Testosterone/adverse effects ; Testosterone/blood ; Testosterone/deficiency ; Treatment Outcome |
مستخلص: | Background: Late-onset hypogonadism (LOH) is a syndrome characterized by clinical and biochemical evidence of low testosterone levels with advancing age. In recent years, several guidelines, position statements and other recommendations have become available. It is unclear whether similar indications are reported in these documents. Objective: To review similarities and differences among available documents on the management of hypogonadism, with a special focus on LOH. Materials and Methods: PubMed, Google and international societies websites were searched on March 2020 for documents published in the last 10 years on the management of hypogonadism and LOH. Results: Nine documents were found, each developed by: (a) the American Urological Association; (b) the British Society for Sexual Medicine; (c) the Canadian Medical Association; (d) the Endocrine Society; (e) the Endocrine Society of Australia; (f) the European Academy of Andrology; (g) the European Association of Urology; (h) the International Consultation for Sexual Medicine; and (i) the International Society for the Study of Aging Male. Discussion: Despite similar principles, differences were found both for the diagnostic workup and follow-up. Particularly, discrepancies were reported both for total and free testosterone levels for diagnosis and for total testosterone for monitoring. Conclusion: Available documents differ in terms of specific recommendations for the management of hypogonadism and LOH. Given the relevant clinical implications of adequate management of these disorders, future guidelines should report more consistent measures to be adopted in clinical practice. (© 2020 American Society of Andrology and European Academy of Andrology.) |
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فهرسة مساهمة: | Keywords: ageing; guidelines; hypogonadism; late-onset hypogonadism; review |
المشرفين على المادة: | 0 (Biomarkers) 3XMK78S47O (Testosterone) |
تواريخ الأحداث: | Date Created: 20200628 Date Completed: 20211011 Latest Revision: 20211011 |
رمز التحديث: | 20231215 |
DOI: | 10.1111/andr.12850 |
PMID: | 32593233 |
قاعدة البيانات: | MEDLINE |
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