دورية أكاديمية
Coagulase-Negative Staphylococci Contained in Gut Microbiota as a Primary Source of Sepsis in Low- and Very Low Birth Weight Neonates.
| العنوان: | Coagulase-Negative Staphylococci Contained in Gut Microbiota as a Primary Source of Sepsis in Low- and Very Low Birth Weight Neonates. |
|---|---|
| المؤلفون: | Golińska E; Jagiellonian University Medical College, 31-121 Cracow, Poland., Strus M; Department of Neonatology, Jagiellonian University, Medical College, 31-501 Cracow, Poland., Tomusiak-Plebanek A; Jagiellonian University Medical College, 31-121 Cracow, Poland., Więcek G; Jagiellonian University Medical College, 31-121 Cracow, Poland., Kozień Ł; Jagiellonian University Medical College, 31-121 Cracow, Poland., Lauterbach R; Department of Neonatology, Jagiellonian University, Medical College, 31-501 Cracow, Poland., Pawlik D; Department of Neonatology, Jagiellonian University, Medical College, 31-501 Cracow, Poland., Rzepecka-Węglarz B; Department of Neonatal Intensive Care, 'UJASTEK' Medical Centre, 31-752 Cracow, Poland., Kędzierska J; Department of Microbiology, University Hospital, 31-501 Cracow, Poland., Dorycka M; Microbiological Laboratory, Diagnostics Inc. Krakow Branch, 31-864 Cracow, Poland., Heczko PB; Jagiellonian University Medical College, 31-121 Cracow, Poland. |
| المصدر: | Journal of clinical medicine [J Clin Med] 2020 Aug 04; Vol. 9 (8). Date of Electronic Publication: 2020 Aug 04. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101606588 Publication Model: Electronic Cited Medium: Print ISSN: 2077-0383 (Print) Linking ISSN: 20770383 NLM ISO Abbreviation: J Clin Med Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI AG, [2012]- |
| مستخلص: | Background: There are only a few reports in the literature about translocation of coagulase-negative staphylococci (CoNS) as a primary cause of sepsis in neonates, although CoNS are among a short list of "translocating" bacteria when present in abundance. Methods: 468 blood samples, 119 stool samples, and 8 catheter tips, from 311 neonates, were tested for presence of microorganisms. CoNS strains isolated from the blood and stool or from blood and catheter tip of the same newborn at approximately the same time were paired and typed with PFGE (Pulse-Field Gel Electrophoresis) method. The strains were then tested for the presence of adherence genes and biofilm formation. Results: The strains with identical PFGE profiles in comparison to those with non-identical profiles differed in terms of the pattern of the virulence genes and showed a lack of the genes related to adherence, but more often presence of IS256, which is related to virulence. They also were phenotypically unable to adhere to intestinal Caco2 cells. Conclusions: A considerable proportion of CoNS strains isolated from bloodstream of VLBW/LWB neonates was identical to the strains isolated from faeces of the same neonates at the same time. These observations may offer indirect evidence indicating that at least some CoNS can translocate from the gastrointestinal tract of the premature neonates into the bloodstream and thus cause generalized infection. |
| References: | APMIS Suppl. 2013 May;(136):1-51. (PMID: 23635385) Microbiome. 2017 Jul 12;5(1):75. (PMID: 28701177) J Hosp Infect. 2017 Mar;95(3):259-267. (PMID: 27955932) J Clin Med. 2019 Oct 21;8(10):. (PMID: 31640253) Infect Drug Resist. 2018 Sep 21;11:1557-1571. (PMID: 30288066) Pediatr Neonatol. 2016 Aug;57(4):265-73. (PMID: 26750406) J Pediatr. 2015 May;166(5):1193-9. (PMID: 25919728) Front Microbiol. 2018 Jan 04;8:2574. (PMID: 29354100) BMC Infect Dis. 2014 Jun 18;14:339. (PMID: 24939563) Indian J Med Microbiol. 2018 Jan-Mar;36(1):124-126. (PMID: 29735842) Clin Microbiol Infect. 2017 Jun;23(6):410.e1-410.e3. (PMID: 28110054) Surgeon. 2012 Dec;10(6):350-6. (PMID: 22534256) Adv Exp Med Biol. 1999;473:11-30. (PMID: 10659341) J Clin Microbiol. 2000 May;38(5):1740-6. (PMID: 10790091) Anaesthesiol Intensive Ther. 2016;48(3):171-4. (PMID: 27188963) Virulence. 2014 Jan 1;5(1):170-8. (PMID: 24185532) Infect Genet Evol. 2014 Mar;22:257-64. (PMID: 23816539) Mol Microbiol. 2017 May;104(3):365-376. (PMID: 28142193) World J Pediatr. 2018 Jun;14(3):269-273. (PMID: 29536341) BMC Gastroenterol. 2014 Nov 18;14:189. (PMID: 25407511) Future Microbiol. 2017 Sep;12:1031-1033. (PMID: 28748707) PLoS One. 2013 May 13;8(5):e62742. (PMID: 23675424) Antimicrob Agents Chemother. 2017 Jul 25;61(8):. (PMID: 28584147) BMC Microbiol. 2006 Dec 19;6:103. (PMID: 17177984) Nat Rev Microbiol. 2009 Aug;7(8):555-67. (PMID: 19609257) Virulence. 2018 Jan 1;9(1):621-633. (PMID: 29405832) J Hosp Infect. 2005 Dec;61(4):342-8. (PMID: 16242209) Front Cell Infect Microbiol. 2017 May 24;7:206. (PMID: 28596942) Eur J Clin Microbiol Infect Dis. 2016 May;35(5):747-54. (PMID: 26873375) Ital J Pediatr. 2020 Feb 5;46(1):16. (PMID: 32024556) J Hosp Infect. 2004 Jun;57(2):126-31. (PMID: 15183242) Clin Dev Immunol. 2013;2013:586076. (PMID: 23762094) J Med Microbiol. 2009 Oct;58(Pt 10):1395-1397. (PMID: 19556370) Pediatr Infect Dis J. 2019 Mar;38(3):308-313. (PMID: 29613973) Pediatr Infect Dis J. 2013 Apr;32(4):389-93. (PMID: 23080292) Biol Neonate. 2004;85(3):151-4. (PMID: 14646338) Eur J Clin Microbiol Infect Dis. 2009 Jun;28(6):655-60. (PMID: 19034541) J Pediatr Gastroenterol Nutr. 2001 Nov;33(5):592-601. (PMID: 11740235) 3 Biotech. 2016 Dec;6(2):233. (PMID: 28330305) J Clin Microbiol. 1995 Sep;33(9):2233-9. (PMID: 7494007) Biomaterials. 2002 Nov;23(21):4233-9. (PMID: 12194526) Bratisl Lek Listy. 2012;113(4):206-10. (PMID: 22502749) APMIS. 2017 Jan;125(1):63-73. (PMID: 27859778) J Hosp Infect. 2002 Dec;52(4):273-80. (PMID: 12473472) |
| معلومات مُعتمدة: | 2014/15/B/NZ6/01856 The National Science Centre; 2018/31/B/NZ6/02443 The National Science Centre |
| فهرسة مساهمة: | Keywords: CoNS; neonates; newborn; sepsis; staphylococcus; translocation |
| تواريخ الأحداث: | Date Created: 20200808 Latest Revision: 20200928 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC7464628 |
| DOI: | 10.3390/jcm9082517 |
| PMID: | 32759861 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder كن أول من يترك تعليقا!