دورية أكاديمية
Radiosurgery treatment planning using conformal arc informed volumetric modulated arc therapy.
العنوان: | Radiosurgery treatment planning using conformal arc informed volumetric modulated arc therapy. |
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المؤلفون: | Giles WM; Duke University Medical Center, Durham, NC, USA. Electronic address: william.giles@duke.edu., Cullom ET; Duke University, Durham, NC, USA., Laryea OA; Duke Kunshan University, Kunshan, Jiangsu, China., Nobah A; King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia., Alves VGL; University of Virginia Health System, Charlottesville, VA, USA., Yin FF; Duke University, Durham, NC, USA; Duke University Medical Center, Durham, NC, USA., Kirkpatrick JP; Duke University, Durham, NC, USA; Duke University Medical Center, Durham, NC, USA., Adamson JD; Duke University, Durham, NC, USA; Duke University Medical Center, Durham, NC, USA. |
المصدر: | Medical dosimetry : official journal of the American Association of Medical Dosimetrists [Med Dosim] 2021 Spring; Vol. 46 (1), pp. 3-12. Date of Electronic Publication: 2020 Aug 15. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Science Country of Publication: United States NLM ID: 8908862 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4022 (Electronic) Linking ISSN: 18734022 NLM ISO Abbreviation: Med Dosim Subsets: MEDLINE |
أسماء مطبوعة: | Publication: <2000->: New York, NY : Elsevier Science Original Publication: [Southwest Harbor, Me. : Beech Hill Pub., |
مواضيع طبية MeSH: | Brain Neoplasms* , Radiosurgery* , Radiotherapy, Intensity-Modulated*, Humans ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted |
مستخلص: | Linac based radiosurgery to multiple metastases is commonly planned with volumetric modulated arc therapy (VMAT) as it effectively achieves high conformality to complex target arrangements. However, as the number of targets increases, VMAT can struggle to block between targets, which can lead to highly modulated and/or nonconformal multi-leaf collimator (MLC) trajectories that unnecessarily irradiation of healthy tissue. In this study we introduce, describe, and evaluate a treatment planning technique called Conformal Arc Informed VMAT (CAVMAT), which aims to reduce the dose to healthy tissue while generating highly conformal treatment plans. CAVMAT is a hybrid technique which combines the conformal MLC trajectories of dynamic conformal arcs with the MLC modulation and versatility of inverse optimization. CAVMAT has 3 main steps. First, targets are assigned to subgroups to maximize MLC blocking between targets. Second, arc weights are optimized to achieve the desired target dose, while minimizing MU variation between arcs. Third, the optimized conformal arc plan serves as the starting point for limited inverse optimization to improve dose conformity to each target. Twenty multifocal VMAT cases were replanned with CAVMAT with 20Gy applied to each target. The total volume receiving 2.5 (Copyright © 2020 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved.) |
فهرسة مساهمة: | Keywords: DCA; SRS; Single-isocenter; VMAT |
تواريخ الأحداث: | Date Created: 20200819 Date Completed: 20211124 Latest Revision: 20211124 |
رمز التحديث: | 20231215 |
DOI: | 10.1016/j.meddos.2020.06.001 |
PMID: | 32807612 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1873-4022 |
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DOI: | 10.1016/j.meddos.2020.06.001 |