دورية أكاديمية
[Research strategy thoughts about acupuncture-moxibustion treatment of chronic atrophic gastritis by suppressing apoptosis via circular RNA].
| العنوان: | [Research strategy thoughts about acupuncture-moxibustion treatment of chronic atrophic gastritis by suppressing apoptosis via circular RNA]. |
|---|---|
| المؤلفون: | Hou YC; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China; School of Acupuncture-moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai 201203., Liu LM; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China; School of Acupuncture-moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai 201203., Chen XT; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China., An XF; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China., Zhao C; School of Acupuncture-moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai 201203., Li J; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China. |
| المصدر: | Zhen ci yan jiu = Acupuncture research [Zhen Ci Yan Jiu] 2020 Aug 25; Vol. 45 (8), pp. 676-81. |
| نوع المنشور: | Journal Article |
| اللغة: | Chinese |
| بيانات الدورية: | Publisher: Institute Of Acupuncture And Moxibustion Country of Publication: China NLM ID: 8507710 Publication Model: Print Cited Medium: Print ISSN: 1000-0607 (Print) Linking ISSN: 10000607 NLM ISO Abbreviation: Zhen Ci Yan Jiu Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Beijing : Institute Of Acupuncture And Moxibustion Original Publication: Beijing, China : Published and distributed by World Books, [1980- |
| مواضيع طبية MeSH: | Gastritis, Atrophic*/therapy , Moxibustion*, Animals ; Apoptosis ; Gastric Mucosa ; RNA, Circular ; Rats ; Research Design |
| مستخلص: | Chronic atrophic gastritis (CAG) is a common digestive disease in clinic. Previous experimental and clinical studies have shown that acupuncture has a positive effect for CAG. Apoptosis of gastric mucosal tissue has been shown to play an important role in the process of gastric atrophy and possibly further carcinogenesis in CAG, and the circular RNA (circRNA), a novel class of non-coding RNA, has been confirmed to play a regulatory role in the downstream pathway of apoptosis by many stu-dies. Accumulated findings of experimental studies showed that acupuncture and moxibustion interventions could suppress apoptosis of the cultured human gastric mucosal epithelial cells and lower apoptotic index of gastric mucosal cells in CAG rats. Therefore, circRNA is likely to mediate the inhibitory effect of acupuncture and moxibustion on apoptosis of gastric mucosal epithelial cells in CAG. In this paper, we systematically summarized 1) the regulation of circRNA on apoptosis, 2) the apoptosis and pathological mechanism of CAG, 3) the effect of acupuncture on apoptosis, and proposed that circRNA is highly likely to be involved in the positive effect of acupuncture and moxibustion interventions for CAG. It is recommended that researches should further reveal the scientific basis of acupuncture and moxibustion therapies in the treatment of CAG by exploring the role of related circRNAs and their downstream target proteins in the gastric mucosal tissues. |
| فهرسة مساهمة: | Keywords: Acupuncture-moxibustion; Apoptosis; Chronic atrophic gastritis; Circular RNA; Gastric mucosal tissue |
| المشرفين على المادة: | 0 (RNA, Circular) |
| تواريخ الأحداث: | Date Created: 20200902 Date Completed: 20201009 Latest Revision: 20201009 |
| رمز التحديث: | 20231215 |
| DOI: | 10.13702/j.1000-0607.190408 |
| PMID: | 32869581 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1000-0607 |
|---|---|
| DOI: | 10.13702/j.1000-0607.190408 |