دورية أكاديمية
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Recommendations and Alerting for Delirium Alleviation in Real-Time (RADAR): Protocol for a pilot randomized controlled trial.

التفاصيل البيبلوغرافية
العنوان: Recommendations and Alerting for Delirium Alleviation in Real-Time (RADAR): Protocol for a pilot randomized controlled trial.
المؤلفون: Vlisides PE; Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, 48170, USA.; Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI, 48109, USA., Ragheb JW; Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, 48170, USA., Leis A; Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, 48170, USA., Schoettinger A; Department of Social Work, Michigan Medicine, Ann Arbor, MI, 48109, USA., Hickey K; University of Michigan School of Nursing, Ann Arbor, MI, 48109, USA., McKinney A; Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, 48170, USA., Brooks J; Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, 48170, USA., Zierau M; Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, 48170, USA., Norcott A; Department of Internal Medicine, Division of Geriatric and Palliative Medicine, University of Michigan Medical School, Ann Arbor, MI, 48109, USA.; Department of Internal Medicine, Division of Geriatric and Palliative Medicine, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, MI, 48105, USA., Yang S; Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, 48170, USA., Avidan MS; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, 63110, USA., Min L; Department of Internal Medicine, Division of Geriatric and Palliative Medicine, University of Michigan Medical School, Ann Arbor, MI, 48109, USA.; Geriatric Research Education and Clinical Care, VA Ann Arbor Healthcare System, Ann Arbor, MI, 48105, USA.
المصدر: F1000Research [F1000Res] 2019 Sep 24; Vol. 8, pp. 1683. Date of Electronic Publication: 2019 Sep 24 (Print Publication: 2019).
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: F1000 Research Ltd Country of Publication: England NLM ID: 101594320 Publication Model: eCollection Cited Medium: Internet ISSN: 2046-1402 (Electronic) Linking ISSN: 20461402 NLM ISO Abbreviation: F1000Res Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : F1000 Research Ltd
مواضيع طبية MeSH: Aftercare* , Decision Support Systems, Clinical* , Postoperative Care*, Delirium/*prevention & control , Delirium/*therapy, Aged ; Delirium/diagnosis ; Humans ; Incidence ; Patient Discharge ; Pilot Projects ; Randomized Controlled Trials as Topic
مستخلص: Background: Delirium is a common and serious complication of major surgery for older adults. Postoperative social and behavioral support (e.g., early mobilization, mealtime assistance) may reduce the incidence and impact of delirium, and these efforts are possible with proactive patient-care programs. This pilot trial tests the hypothesis that a multicomponent decision support system, which sends automated alerts and recommendations to patient-care programs and family members for high-risk patients, will improve the postoperative environment for neurocognitive and clinical recovery. Methods: This will be a randomized, controlled, factorial pilot trial at a large academic medical center. High-risk, non-cardiac surgery patients (≥70 years old) will be recruited. Patients will be allocated to a usual care group (n=15), Hospital Elder Life Program (HELP)-based paging system (n=15), family-based paging system (n=15), or combined HELP- and family-based system (n=15). The primary outcome will be the presence of delirium, defined by positive long-form Confusion Assessment Method screening. Secondary outcomes will include additional HELP- and family-based performance metrics along with various neurocognitive and clinical recovery measures. Exploratory outcomes include the incidence of positive family-based delirium assessments post-discharge, 36-item Short Form Survey, PROMIS Cognitive Function Abilities Subset 4a, and 30-day readmission rates. Ethics and dissemination: This trial has received approval by the University of Michigan Medical Institutional Review Board (IRBMED). Dissemination plans include presentation at scientific conferences, publication in medical journals, and distribution via educational and news media. Registration: ClinicalTrials.gov Identifier NCT04007523, registered on 7/3/2019.
Competing Interests: No competing interests were disclosed.
(Copyright: © 2020 Vlisides PE et al.)
References: Crit Care Med. 2013 Sep;41(9 Suppl 1):S116-27. (PMID: 23989089)
Anesthesiology. 2012 Oct;117(4):717-25. (PMID: 22990178)
J Clin Epidemiol. 2014 Mar;67(3):267-77. (PMID: 24275499)
JAMA. 2000 May 24-31;283(20):2701-11. (PMID: 10819955)
BMJ. 2016 Oct 24;355:i5239. (PMID: 27777223)
J Am Geriatr Soc. 2004 Nov;52(11):1875-82. (PMID: 15507065)
Health Serv Res. 2012 Jun;47(3 Pt 1):1051-67. (PMID: 22092292)
Clin Infect Dis. 2019 Nov 13;69(11):1837-1844. (PMID: 30980082)
J Am Geriatr Soc. 2012 Nov;60(11):2121-6. (PMID: 23039310)
JAMA Surg. 2015 Dec;150(12):1134-40. (PMID: 26352694)
BMJ Open. 2018 Nov 21;8(11):e023137. (PMID: 30467132)
N Engl J Med. 2012 Jul 5;367(1):30-9. (PMID: 22762316)
J Neurosurg Anesthesiol. 2019 Apr;31(2):212-217. (PMID: 30557230)
Ann Intern Med. 1999 Aug 3;131(3):165-73. (PMID: 10428732)
Am J Geriatr Psychiatry. 2018 Oct;26(10):1015-1033. (PMID: 30076080)
Ann Intern Med. 1990 Dec 15;113(12):941-8. (PMID: 2240918)
Arch Intern Med. 2008 Jan 14;168(1):27-32. (PMID: 18195192)
J Am Geriatr Soc. 2018 Jul;66(6):1218-1225. (PMID: 29671281)
Ann Surg. 2017 Apr;265(4):647-653. (PMID: 27501176)
J Am Geriatr Soc. 2006 Oct;54(10):1578-89. (PMID: 17038078)
BMC Health Serv Res. 2006 Apr 03;6:44. (PMID: 16584553)
Anesthesiology. 2013 Aug;119(2):295-302. (PMID: 23681144)
Lancet. 2017 Jul 15;390(10091):267-275. (PMID: 28576285)
JAMA. 1994 Jan 12;271(2):134-9. (PMID: 8264068)
Anesth Analg. 2019 May;128(5):944-952. (PMID: 30768457)
JAMA. 2010 Jul 28;304(4):443-51. (PMID: 20664045)
N Engl J Med. 1999 Mar 4;340(9):669-76. (PMID: 10053175)
JAMA Surg. 2017 Dec 01;152(12):1126-1133. (PMID: 28768325)
JAMA. 2017 Sep 26;318(12):1161-1174. (PMID: 28973626)
J Am Geriatr Soc. 2005 Sep;53(9):1455-61. (PMID: 16137272)
Acta Psychiatr Scand. 1983 Jun;67(6):361-70. (PMID: 6880820)
Implement Sci. 2009 Aug 07;4:50. (PMID: 19664226)
Alzheimers Dement. 2016 Jul;12(7):766-75. (PMID: 27103261)
Psychol Health Med. 2017 Jan;22(1):121-128. (PMID: 26899740)
F1000Res. 2019 Sep 24;8:1683. (PMID: 32934794)
Ann Intern Med. 2013 Feb 5;158(3):200-7. (PMID: 23295957)
J Gerontol Nurs. 2010 Sep;36(9):22-33; quiz 34-5. (PMID: 20438016)
BMJ. 2015 May 08;350:h2147. (PMID: 25956159)
معلومات مُعتمدة: P30 AG024824 United States AG NIA NIH HHS; UL1 TR002240 United States TR NCATS NIH HHS
فهرسة مساهمة: Keywords: Clinical Trial Protocol; Decision Support Systems; Delirium; Feasibility Studies; Perioperative Care
سلسلة جزيئية: ClinicalTrials.gov NCT04007523
تواريخ الأحداث: Date Created: 20200917 Date Completed: 20201013 Latest Revision: 20240329
رمز التحديث: 20240329
مُعرف محوري في PubMed: PMC7471625
DOI: 10.12688/f1000research.20597.2
PMID: 32934794.2. Version: 2. Publisher Version ID: 2. Version Date: 2020/09/01
قاعدة البيانات: MEDLINE
الوصف
تدمد:2046-1402
DOI:10.12688/f1000research.20597.2