دورية أكاديمية
أعرض في EDS

Informant Questionnaires in Dedicated Memory Clinics: How Much Do They Contribute?

التفاصيل البيبلوغرافية
العنوان: Informant Questionnaires in Dedicated Memory Clinics: How Much Do They Contribute?
المؤلفون: Novak L; University Hospital of Old Age Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.; Faculty of Medicine, University of Bern, Bern, Switzerland., Wyss P; University Hospital of Old Age Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland., Lenouvel E; University Hospital of Old Age Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland., Abdulkadir A; University Hospital of Old Age Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland., Klöppel S; University Hospital of Old Age Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.
المصدر: Journal of the American Geriatrics Society [J Am Geriatr Soc] 2021 Jan; Vol. 69 (1), pp. 106-113. Date of Electronic Publication: 2020 Sep 16.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Blackwell Science Country of Publication: United States NLM ID: 7503062 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-5415 (Electronic) Linking ISSN: 00028614 NLM ISO Abbreviation: J Am Geriatr Soc Subsets: MEDLINE
أسماء مطبوعة: Publication: Malden, MA : Blackwell Science
Original Publication: New York [etc.]
مواضيع طبية MeSH: Diagnosis, Differential* , Surveys and Questionnaires*, Cognitive Dysfunction/*diagnosis , Dementia/*diagnosis , Neuropsychological Tests/*statistics & numerical data, Activities of Daily Living/psychology ; Aged ; Aged, 80 and over ; Caregivers/psychology ; Female ; Humans ; Male ; Models, Statistical ; Retrospective Studies
مستخلص: Background/objectives: The diagnostic process in a university memory clinic is based largely on cognitive testing. However, input from informants, acquired through interview or questionnaires, may significantly impact diagnosis. We sought to evaluate whether informant questionnaires for basic and instrumental activities of daily living, or for identifying progressive cognitive decline would improve diagnostic predictability of neurodegenerative disorders compared with either the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) neuropsychological test battery or the Mini-Mental State Examination score alone.
Design: Retrospective data analysis using logit models.
Setting: University hospital outpatient memory clinic.
Participants: A total of 394 patients with dementia, mild cognitive impairment (MCI), depression, or subjective cognitive impairment were assessed.
Measurements: Bristol Activities of Daily Living Scale, Functional Activities Questionnaire, Informant Questionnaire on Cognitive Decline in the Elderly, and the Physical Self-Maintenance Scale questionnaires were obtained. Analyses through logit models were performed to predict outcome diagnoses, based on cognitive scores alone or in combination with one or more informant questionnaires.
Results: The four questionnaires were highly correlated (.31-.86). The addition of informant questionnaires improved diagnostic predictability between differential diagnoses of MCI and dementia, or dementia and depression. However, the misprediction rate was reduced by up to 6 percentage points only. Adding more than one questionnaire or all CERAD subtests instead of their sum score never improved prediction in regularized logit models to a clinically relevant extent.
Conclusion: Although questionnaires contribute to a statistically better prediction of the outcome diagnosis, for some sets of differential diagnoses, the benefit may not be clinically pertinent when routine semistructured informant interviews are used by trained personnel. However, standardized assessment, particularly when patients are seen longitudinally, should not be underestimated.
(© 2020 The American Geriatrics Society.)
References: Harrison JK, Fearon P, Noel-Storr AH, McShane R, Stott DJ, Quinn TJ. Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within a secondary care setting. Cochrane Database Syst Rev. 2015;3(3):CD010772.
Creavin ST, Wisniewski S, Noel-Storr AH, et al. Mini-Mental State Examination (MMSE) for the detection of dementia in clinically unevaluated people aged 65 and over in community and primary care populations. Cochrane Database Syst Rev. 2016;1(1):CD011145.
Kopecek M, Bezdicek O, Sulc Z, Lukavsky J, Stepankova H. Montreal Cognitive Assessment and Mini-Mental State Examination reliable change indices in healthy older adults. Int J Geriatr Psychiatry. 2017;32(8):868-875.
Folstein MF, Folstein SE, McHugh PR. “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12(3):189-198.
Morris JC, Mohs RC, Rogers H, Fillenbaum G, Heyman A. Consortium to Establish a Registry for Alzheimerʼs disease (CERAD) clinical and neuropsychological assessment of Alzheimerʼs disease. Psychopharmacol Bull. 1988;24(4):641-652.
Morris JC, Heyman A, Mohs RC, et al. The Consortium to Establish a Registry for Alzheimerʼs disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimerʼs disease. Neurology. 1989;39(9):1159-1165.
Schmid NS, Ehrensperger MM, Berres M, Beck IR, Monsch AU. The extension of the German CERAD neuropsychological assessment battery with tests assessing subcortical, executive and frontal functions improves accuracy in dementia diagnosis. Dement Geriatr Cogn Dis Extra. 2014;4(2):322-334.
Carr DB, Gray S, Baty J, Morris JC. The value of informant vs individualʼs complaints of memory impairment in early dementia. Neurology. 2000;55(11):1724-1726.
Sikkes SAM, De Lange-de Klerk ES, Pijnenburg YAL, Scheltens P, Uitdehaag BMJ. A systematic review of Instrumental Activities of Daily Living scales in dementia: room for improvement. J Neurol Neurosurg Psychiatry. 2009;80(1):7-12.
German Association for Psychiatry, Psychotherapy and Psychosomatics (DGPPN), German Association for Neurology (DGN). S3-guidelines dementia. Berlin, Heidelberg: Springer Berlin Heidelberg; 2017. (interdisciplinary S3-practice guidelines). https://ebookcentral.proquest.com/lib/gbv/detail.action?docID=5097005. Accessed October 2019.
Bucks RS, Ashworth DL, Wilcock GK, Siegfried K. Assessment of activities of daily living in dementia: development of the Bristol Activities of Daily Living Scale. Age Ageing. 1996;25(2):113-120.
Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist. 1969;9(3):179-186.
Pfeffer RI, Kurosaki TT, Harrah CH, Chance JM, Filos S. Measurement of functional activities in older adults in the community. J Gerontol. 1982;37(3):323-329.
Chandler MJ, Lacritz LH, Hynan LS, et al. A total score for the CERAD neuropsychological battery. Neurology. 2005;65(1):102-106.
Jessen F, Wolfsgruber S, Wiese B, et al. AD dementia risk in late MCI, in early MCI, and in subjective memory impairment. Alzheimers Dement. 2014;10(1):76-83.
World Health Organization (WHO). International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10): ICD-10; 2016. https://icd.who.int/browse10/2016/en. Accessed April 2019.
Jessen F, Spottke A, Boecker H, et al. Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimerʼs disease (DELCODE). Alzheimers Res Ther. 2018;10(1):15.
Bucks RS, Haworth J. Bristol Activities of Daily Living Scale: a critical evaluation. Expert Rev Neurother. 2002;2(5):669-676.
Liang F-W, Chan W, Chen P-J, Zimmerman C, Waring S, Doody R. Cognitively-related basic activities of daily living impairment greatly increases the risk of death in Alzheimers disease. PLoS One. 2016;11(8):e0160671.
Jorm AF, Jacomb PA. The Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE): socio-demographic correlates, reliability, validity and some norms. Psychol Med. 1989;19(4):1015-1022.
Ding Y, Niu J, Zhang Y, et al. Informant questionnaire on cognitive decline in the elderly (IQCODE) for assessing the severity of dementia in patients with Alzheimerʼs disease. BMC Geriatr. 2018;18(1):146.
Ehrensperger MM, Berres M, Taylor KI, Monsch AU. Screening properties of the German IQCODE with a two-year time frame in MCI and early Alzheimerʼs disease. Int Psychogeriatr. 2010;22(1):91-100.
Robin X, Turck N, Hainard A, et al. pROC: an open-source package for R and S+ to analyze and compare ROC curves. BMC Bioinformatics. 2011;12:77.
Bürge M, Bieri G, Brühlmeier M, et al. Die Empfehlungen der Swiss Memory Clinics für die Diagnostik der Demenzerkrankungen. Praxis (Bern 1994). 2018;107(8):435-451.
Thompson CL, Henry JD, Rendell PG, Withall A, Brodaty H. How valid are subjective ratings of prospective memory in mild cognitive impairment and early dementia? Gerontology. 2015;61(3):251-257.
فهرسة مساهمة: Keywords: basic and instrumental activities of daily living; cognitive decline; dementia diagnostics; informant questionnaires; memory clinic
تواريخ الأحداث: Date Created: 20200916 Date Completed: 20210914 Latest Revision: 20210914
رمز التحديث: 20240829
DOI: 10.1111/jgs.16818
PMID: 32936455
قاعدة البيانات: MEDLINE
الوصف
تدمد:1532-5415
DOI:10.1111/jgs.16818