دورية أكاديمية
أعرض في EDS

Volume Elastic Modulus, Vascular Function, and Vascular Structure in Patients with Cardiovascular Risk Factors.

التفاصيل البيبلوغرافية
العنوان: Volume Elastic Modulus, Vascular Function, and Vascular Structure in Patients with Cardiovascular Risk Factors.
المؤلفون: Maruhashi T; Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University., Kajikawa M; Division of Regeneration and Medicine, Hiroshima University Hospital., Kishimoto S; Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University., Takaeko Y; Cardiovascular Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University., Yamaji T; Cardiovascular Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University., Harada T; Cardiovascular Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University., Hashimoto Y; Cardiovascular Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University., Han Y; Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University., Aibara Y; Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University., Mohamad Yusoff F; Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University., Chayama K; Department of Medicine and Molecular Science, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima University., Nakashima A; Department of Stem Cell Biology and Medicine, Graduate School of Biomedical and Sciences, Hiroshima University., Goto C; Department of Rehabilitation, Faculty of General Rehabilitation, Hiroshima International University., Nakano Y; Cardiovascular Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University., Higashi Y; Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University.; Division of Regeneration and Medicine, Hiroshima University Hospital.
المصدر: Journal of atherosclerosis and thrombosis [J Atheroscler Thromb] 2021 Sep 01; Vol. 28 (9), pp. 963-973. Date of Electronic Publication: 2020 Oct 23.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Japan Atherosclerosis Society Country of Publication: Japan NLM ID: 9506298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-3873 (Electronic) Linking ISSN: 13403478 NLM ISO Abbreviation: J Atheroscler Thromb Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Tokyo : Japan Atherosclerosis Society
مواضيع طبية MeSH: Brachial Artery/*physiopathology , Cardiovascular Diseases/*etiology, Aged ; Atherosclerosis/etiology ; Atherosclerosis/pathology ; Atherosclerosis/physiopathology ; Brachial Artery/pathology ; Cardiovascular Diseases/pathology ; Cardiovascular Diseases/physiopathology ; Elastic Modulus ; Endothelium, Vascular/pathology ; Endothelium, Vascular/physiopathology ; Female ; Heart Disease Risk Factors ; Humans ; Male ; Middle Aged ; Vasodilation
مستخلص: Aims: Volume elastic modulus (V E ), an index of arterial elasticity, and arterial diameter of the brachial artery can be automatically measured by a newly developed oscillometric device. We investigated the associations of V E with flow-mediated vasodilation (FMD), an index of endothelium-dependent vasodilation, nitroglycerine-induced vasodilation (NID), an index of endothelium-independent vasodilation, and intima-media thickness (IMT) of the brachial artery and association of oscillometrically measured brachial artery diameter with ultrasonographically measured brachial artery diameter in patients with cardiovascular risk factors.
Methods: Oscillometric measurements of V E and brachial artery diameter and ultrasound measurements of brachial artery diameter, FMD, NID, and IMT of the brachial artery were performed in 50 patients with cardiovascular risk factors.
Results: The mean values were 2.1±0.4 mmHg/% for V E , 0.31±0.05 mm for brachial IMT, 4.48±0.70 mm for oscillometric brachial artery diameter, and 4.30±0.55 mm for ultrasound brachial artery diameter. V E significantly correlated with brachial IMT (r=0.51, P＜0.001), whereas there was no significant correlation of V E with FMD (r=-0.08, P=0.58) or NID (r=0.07, P=0.61). Multivariate analysis revealed that V E was significantly associated with brachial IMT (β=0.33, P=0.04). Oscillometric brachial artery diameter significantly correlated with ultrasound brachial artery diameter (r=0.79, P＜0.001). The Bland-Altman plot showed good agreement between oscillometric brachial artery diameter and ultrasound brachial artery diameter (mean difference, -0.17 mm; limits of agreement, -1.03 mm to 0.69 mm).
Conclusions: In patients with cardiovascular risk factors, V E may represent atherosclerotic structural alterations of the vascular wall but not vascular function. The accuracy of oscillometric measurement of brachial artery diameter is acceptable.
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فهرسة مساهمة: Keywords: Brachial artery diameter; Endothelium-dependent vasodilation; Endothelium-independent vasodilation; Intima-media thickness; Volume elastic modulus
تواريخ الأحداث: Date Created: 20201026 Date Completed: 20220215 Latest Revision: 20220215
رمز التحديث: 20240829
مُعرف محوري في PubMed: PMC8532062
DOI: 10.5551/jat.59261
PMID: 33100278
قاعدة البيانات: MEDLINE
الوصف
تدمد:1880-3873
DOI:10.5551/jat.59261