دورية أكاديمية
Comparison of Skin Antiseptic Agents and the Role of 0.01% Hypochlorous Acid.
| العنوان: | Comparison of Skin Antiseptic Agents and the Role of 0.01% Hypochlorous Acid. |
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| المؤلفون: | Tran AQ; Department of Ophthalmology, Oculoplastic and Reconstructive Surgery, University of Miami Bascom Palmer Eye Institute, Miami, FL, USA., Topilow N; Department of Ophthalmology, Oculoplastic and Reconstructive Surgery, University of Miami Bascom Palmer Eye Institute, Miami, FL, USA., Rong A; Department of Ophthalmology, Oculoplastic and Reconstructive Surgery, University of Miami Bascom Palmer Eye Institute, Miami, FL, USA., Persad PJ; Department of Statistics, University of Miami Bascom Palmer Eye Institute, Miami, FL, USA., Lee MC; Westminster High School, Palmetto Bay, FL, USA., Lee JH; Westminster High School, Palmetto Bay, FL, USA., Anagnostopoulos AG; Department of Ophthalmology, Oculoplastic and Reconstructive Surgery, University of Miami Bascom Palmer Eye Institute, Miami, FL, USA., Lee WW; Department of Ophthalmology, Oculoplastic and Reconstructive Surgery, University of Miami Bascom Palmer Eye Institute, Miami, FL, USA. |
| المصدر: | Aesthetic surgery journal [Aesthet Surg J] 2021 Sep 14; Vol. 41 (10), pp. 1170-1175. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 9707469 Publication Model: Print Cited Medium: Internet ISSN: 1527-330X (Electronic) Linking ISSN: 1090820X NLM ISO Abbreviation: Aesthet Surg J Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2015-: Oxford : Oxford University Press Original Publication: St. Louis, MO : Mosby-Year Book, c1997- |
| مواضيع طبية MeSH: | Anti-Infective Agents, Local* , Dermatologic Agents*, 2-Propanol ; Chlorhexidine ; Humans ; Hypochlorous Acid ; Povidone-Iodine ; Prospective Studies ; Skin |
| مستخلص: | Background: Hypochlorous acid (HA) has both anti-microbial and wound-healing properties with a growing role for utilization in pre-procedural care on the face. Objectives: The authors sought to compare the antiseptic property of 0.01% HA solution, 5% povidone iodine (PI), 4% chlorhexidine gluconate (CHG), and 70% isopropyl alcohol (IPA) antiseptic on facial skin. Methods: This was a prospective single-center clinical trial. Results: A total of 21 participants were recruited. Bacterial growth was seen in CHG (10%), IPA (71%), PI (81%), and HA (95%) of specimens (P < 0.001). CHG had less growth compared with HA (P = <0.001), IPA (P = <0.001), and PI (P = <0.001). No difference in bacterial growth was noted between HA and IPA (P = 0.063) or HA and PI (P = 0.25). Significant differences in mono-microbial and poly-microbial growth were seen between HA and IPA (P = 0.046) and HA and CHG (P = <0.001). Staphylococcus epidermidis grew less frequently in CHG (10%), followed by IPA (29%), PI (71%), and HA (71%). Staphylococcus capitis grew less frequently in CHG (0%), followed by PI (14%), HA (24%), and IPA (29%). Conclusions: CHG reduced the bacterial growth compared with HA, PI, and IPA. However, HA, PI, and IPA had insignificant differences in bactericidal effects. Our study provides a supporting role of HA to be considered as an antiseptic. (© 2020 The Aesthetic Society.) |
| التعليقات: | Comment in: Aesthet Surg J. 2021 Sep 14;41(10):1176-1178. doi: 10.1093/asj/sjab008. (PMID: 33942074) |
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| معلومات مُعتمدة: | P30 EY014801 United States EY NEI NIH HHS |
| المشرفين على المادة: | 0 (Anti-Infective Agents, Local) 0 (Dermatologic Agents) 712K4CDC10 (Hypochlorous Acid) 85H0HZU99M (Povidone-Iodine) ND2M416302 (2-Propanol) R4KO0DY52L (Chlorhexidine) |
| تواريخ الأحداث: | Date Created: 20201128 Date Completed: 20210921 Latest Revision: 20240923 |
| رمز التحديث: | 20240923 |
| مُعرف محوري في PubMed: | PMC8438591 |
| DOI: | 10.1093/asj/sjaa322 |
| PMID: | 33247899 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1527-330X |
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| DOI: | 10.1093/asj/sjaa322 |