دورية أكاديمية
β-Carotene: Preventive Role for Type 2 Diabetes Mellitus and Obesity: A Review.
العنوان: | β-Carotene: Preventive Role for Type 2 Diabetes Mellitus and Obesity: A Review. |
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المؤلفون: | Marcelino G; Post Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Machate DJ; Group of Spectroscopy and Bioinformatics Applied Biodiversity and Health (GEBABS), Graduate Program in Science of Materials, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Freitas KC; Post Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Hiane PA; Post Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Maldonade IR; Laboratory of Food Science and Technology, Brazilian Agricultural Research Corporation (Embrapa Vegetables), Brasília 70275-970, Brazil., Pott A; Laboratory of Botany, Institute of Biosciences, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Asato MA; Faculty of Medicine, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Candido CJ; Post Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil., Guimarães RCA; Post Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil. |
المصدر: | Molecules (Basel, Switzerland) [Molecules] 2020 Dec 09; Vol. 25 (24). Date of Electronic Publication: 2020 Dec 09. |
نوع المنشور: | Journal Article; Review |
اللغة: | English |
بيانات الدورية: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI, c1995- |
مواضيع طبية MeSH: | Diabetes Mellitus, Type 2/*prevention & control , Obesity/*prevention & control , beta Carotene/*pharmacology, Animals ; Antioxidants/pharmacology ; Diabetes Mellitus, Type 2/metabolism ; Humans ; Insulin Resistance ; Lipid Metabolism/drug effects ; Obesity/metabolism ; Oxidative Stress/drug effects ; beta Carotene/pharmacokinetics |
مستخلص: | Carotenoids are vital antioxidants for plants and animals. They protect cells from oxidative events and act against the inflammatory process and carcinogenesis. Among the most abundant carotenoids in human and foods is β-carotene. This carotenoid has the highest level of provitamin A activity, as it splits into two molecules of retinol through the actions of the cytosolic enzymes: β-carotene-15,15'-monooxygenase (β-carotene-15,15'-oxygenase 1) and β-carotene-9',10'-dioxygenase (β-carotene-9',10'-oxygenase 2). The literature supports the idea that β-carotene acts against type 2 diabetes mellitus, cardiovascular diseases, obesity, and metabolic syndrome. Due to the many processes involved in β-carotene biosynthesis and metabolic function, little is known about such components, since many mechanisms have not yet been fully elucidated. Therefore, our study concisely described the relationships between the consumption of carotenoids, with emphasis on β-carotene, and obesity and type 2 diabetes mellitus and its associated parameters in order to understand the preventive role of carotenoids better and encourage their consumption. |
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معلومات مُعتمدة: | 001 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior |
فهرسة مساهمة: | Keywords: antioxidants; dyslipidemia; insulin resistance; oxidative stress |
المشرفين على المادة: | 0 (Antioxidants) 01YAE03M7J (beta Carotene) |
تواريخ الأحداث: | Date Created: 20201215 Date Completed: 20210903 Latest Revision: 20210903 |
رمز التحديث: | 20221213 |
مُعرف محوري في PubMed: | PMC7763535 |
DOI: | 10.3390/molecules25245803 |
PMID: | 33316948 |
قاعدة البيانات: | MEDLINE |
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