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Histological subtype of gastric adenocarcinoma: two cases of mixed fundic and pyloric mucosa-type adenocarcinoma.

التفاصيل البيبلوغرافية
العنوان: Histological subtype of gastric adenocarcinoma: two cases of mixed fundic and pyloric mucosa-type adenocarcinoma.
المؤلفون: Takahashi H; Department of Gastroenterology, Fukuoka University Chikushi Hospital, 1-1-1 Zokumyoin Chikushino, Fukuoka 818-8052, Japan., Yao K; Department of Endoscopy, Fukuoka University Chikushi Hospital, Chikushino, 818-8052, Japan., Ueo T; Department of Gastroenterology, Oita Red Cross Hospital, Oita, 870-0033, Japan., Nagahama T; Department of Endoscopy, Fukuoka University Chikushi Hospital, Chikushino, 818-8052, Japan., Imamura K; Department of Gastroenterology, Fukuoka University Chikushi Hospital, 1-1-1 Zokumyoin Chikushino, Fukuoka 818-8052, Japan., Chuman K; Department of Gastroenterology, Fukuoka University Chikushi Hospital, 1-1-1 Zokumyoin Chikushino, Fukuoka 818-8052, Japan., Tanabe H; Department of Pathology, Fukuoka University Chikushi Hospital, Chikushino, 818-8052, Japan., Iwashita A; Department of Pathology, Fukuoka University Chikushi Hospital, Chikushino, 818-8052, Japan., Ueki T; Department of Gastroenterology, Fukuoka University Chikushi Hospital, 1-1-1 Zokumyoin Chikushino, Fukuoka 818-8052, Japan.
المصدر: Ecancermedicalscience [Ecancermedicalscience] 2020 Nov 13; Vol. 14, pp. 1143. Date of Electronic Publication: 2020 Nov 13 (Print Publication: 2020).
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: ecancer Country of Publication: England NLM ID: 101392236 Publication Model: eCollection Cited Medium: Print ISSN: 1754-6605 (Print) Linking ISSN: 17546605 NLM ISO Abbreviation: Ecancermedicalscience Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: Bristol, UK : ecancer
Original Publication: Bristol, UK : Cancer Intelligence
مستخلص: Adenocarcinomas with differentiation towards fundic or pyloric glands are rare histological subtypes. We herein describe two cases of new histological subtypes: mixed fundic and pyloric mucosa-type adenocarcinoma detected in Helicobacter pylori uninfected patients. The first patient was a woman in her 40s. A glossy, reddish, nodular lesion with a flat elevated whitish area was detected at the gastric fundus. When the nodular lesion was visualised with magnifying narrow-band imaging (M-NBI), an absent microvascular pattern plus an irregular microsurface pattern with a demarcation line was observed. The second patient was a woman in her 60s. A glossy, reddish, elevated lesion was detected at the gastric body. M-NBI finding was a regular microvascular pattern plus a regular microsurface pattern with a demarcation line. Histological examination of the resected specimens from both cases showed a very well- to well-differentiated adenocarcinoma which has differentiation towards the mixed fundic and pyloric mucosa. The histological and serological findings of both cases indicated the absence of H. pylori infection. The present two cases demonstrate further evidence of a new histological subtype of gastric adenocarcinoma: mixed fundic and pyloric mucosa-type adenocarcinoma, which has distinct characteristic endoscopic findings.
Competing Interests: The authors declare that they have no conflicts of interest regarding the publication of this paper.
(© the authors; licensee ecancermedicalscience.)
References: Endoscopy. 2009 May;41(5):462-7. (PMID: 19418401)
Helicobacter. 2011 Dec;16(6):415-9. (PMID: 22059391)
Clin J Gastroenterol. 2017 Jun;10(3):224-228. (PMID: 28258560)
Endoscopy. 2014 Feb;46(2):153-7. (PMID: 24338239)
Dig Endosc. 2012 Nov;24(6):419-25. (PMID: 23078433)
N Engl J Med. 2001 Sep 13;345(11):784-9. (PMID: 11556297)
Endoscopy. 2006 Aug;38(8):819-24. (PMID: 17001572)
Gastric Cancer. 2014;17(3):469-77. (PMID: 24037102)
Am J Surg Pathol. 2010 May;34(5):609-19. (PMID: 20410811)
فهرسة مساهمة: Keywords: early gastric cancer; gastric phenotype; magnifying narrow-band imaging
تواريخ الأحداث: Date Created: 20201221 Latest Revision: 20201222
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC7738269
DOI: 10.3332/ecancer.2020.1143
PMID: 33343702
قاعدة البيانات: MEDLINE
الوصف
تدمد:1754-6605
DOI:10.3332/ecancer.2020.1143