دورية أكاديمية
أعرض في EDS

Cancer-Associated Fibroblasts in the Breast Tumor Microenvironment.

التفاصيل البيبلوغرافية
العنوان: Cancer-Associated Fibroblasts in the Breast Tumor Microenvironment.
المؤلفون: Giorello MB; Laboratorio de Inmunohematología (IBYME) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Biología y Medicina Experimental, Vuelta de Obligado 2490, CP, 1428, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina. mbgiorello@gmail.com., Borzone FR; Laboratorio de Inmunohematología (IBYME) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Biología y Medicina Experimental, Vuelta de Obligado 2490, CP, 1428, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina., Labovsky V; Laboratorio de Inmunohematología (IBYME) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Biología y Medicina Experimental, Vuelta de Obligado 2490, CP, 1428, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina., Piccioni FV; Laboratorio de Oncología Molecular y Nuevos Blancos Terapéuticos (IBYME) y Laboratorio de Inmunohematología (IBYME) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Biología y Medicina Experimental, Vuelta de Obligado 2490, CP, 1428, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina., Chasseing NA; Laboratorio de Inmunohematología (IBYME) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Biología y Medicina Experimental, Vuelta de Obligado 2490, CP, 1428, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina. achasseing@ibyme.conicet.gov.ar.
المصدر: Journal of mammary gland biology and neoplasia [J Mammary Gland Biol Neoplasia] 2021 Jun; Vol. 26 (2), pp. 135-155. Date of Electronic Publication: 2021 Jan 04.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 9601804 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7039 (Electronic) Linking ISSN: 10833021 NLM ISO Abbreviation: J Mammary Gland Biol Neoplasia Subsets: MEDLINE
أسماء مطبوعة: Publication: 1999- : New York, NY : Kluwer Academic/Plenum Publishers
Original Publication: New York : Plenum Press, c1996-
مواضيع طبية MeSH: Breast/*pathology , Breast Neoplasms/*pathology , Cancer-Associated Fibroblasts/*pathology , Neoplasm Recurrence, Local/*epidemiology, Breast/cytology ; Breast Neoplasms/mortality ; Breast Neoplasms/therapy ; Carcinogenesis/pathology ; Disease-Free Survival ; Female ; Humans ; Neoplasm Invasiveness/pathology ; Neoplasm Recurrence, Local/pathology ; Neoplasm Recurrence, Local/prevention & control ; Prognosis ; Tumor Microenvironment
مستخلص: Years of investigation have shed light on a theory in which breast tumor epithelial cells are under the effect of the stromal microenvironment. This review aims to discuss recent findings concerning the phenotypic and functional characteristics of cancer associated fibroblasts (CAFs) and their involvement in tumor evolution, as well as their potential implications for anti-cancer therapy. In this manuscript, we reviewed that CAFs play a fundamental role in initiation, growth, invasion, and metastasis of breast cancer, and also serve as biomarkers in the clinical diagnosis, therapy, and prognosis of this disease.
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فهرسة مساهمة: Keywords: Biomarkers of CAFs; Breast cancer; Cancer associated fibroblasts; Immunosuppression activity; Pro-tumoral activity
تواريخ الأحداث: Date Created: 20210105 Date Completed: 20220201 Latest Revision: 20220201
رمز التحديث: 20240829
DOI: 10.1007/s10911-020-09475-y
PMID: 33398516
قاعدة البيانات: MEDLINE
الوصف
تدمد:1573-7039
DOI:10.1007/s10911-020-09475-y