تقرير
Emphysematous pyelonephritis caused by C. glabrata.
| العنوان: | Emphysematous pyelonephritis caused by C. glabrata. |
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| المؤلفون: | Schutz EA; Universidade Estadual do Oeste do Paraná (Unioeste), Centro de Ciências Médicas e Farmacêuticas (CCMF), Hospital Universitário do Oeste do Paraná (HUOP), Cascavel, PR, Brasil., Zabott AP; Universidade Estadual do Oeste do Paraná (Unioeste), Centro de Ciências Médicas e Farmacêuticas (CCMF), Hospital Universitário do Oeste do Paraná (HUOP), Cascavel, PR, Brasil., Boaretto RBB; Universidade Estadual do Oeste do Paraná (Unioeste), Centro de Ciências Médicas e Farmacêuticas (CCMF), Hospital Universitário do Oeste do Paraná (HUOP), Cascavel, PR, Brasil., Toyama G; Universidade Estadual do Oeste do Paraná (Unioeste), Centro de Ciências Médicas e Farmacêuticas (CCMF), Hospital Universitário do Oeste do Paraná (HUOP), Cascavel, PR, Brasil., Morais CF; Universidade Estadual do Oeste do Paraná (Unioeste), Centro de Ciências Médicas e Farmacêuticas (CCMF), Hospital Universitário do Oeste do Paraná (HUOP), Cascavel, PR, Brasil., Moroni JG; Universidade Estadual do Oeste do Paraná (Unioeste), Centro de Ciências Médicas e Farmacêuticas (CCMF), Hospital Universitário do Oeste do Paraná (HUOP), Cascavel, PR, Brasil., Oliveira CS; Universidade Estadual do Oeste do Paraná (Unioeste), Centro de Ciências Médicas e Farmacêuticas (CCMF), Hospital Universitário do Oeste do Paraná (HUOP), Cascavel, PR, Brasil. |
| المصدر: | Jornal brasileiro de nefrologia [J Bras Nefrol] 2022 Jul-Sep; Vol. 44 (3), pp. 447-451. |
| نوع المنشور: | Case Reports |
| اللغة: | English; Portuguese |
| بيانات الدورية: | Publisher: Sociedade Brasileira de Nefrologia Country of Publication: Brazil NLM ID: 9426946 Publication Model: Print Cited Medium: Internet ISSN: 2175-8239 (Electronic) Linking ISSN: 01012800 NLM ISO Abbreviation: J Bras Nefrol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: São Paulo : Sociedade Brasileira de Nefrologia Original Publication: São Paulo, Brazil : Associação Medica Brasileira |
| مواضيع طبية MeSH: | Diabetes Complications* , Emphysema*/etiology , Emphysema*/therapy , Pyelonephritis*/complications , Pyelonephritis*/diagnosis, Candida glabrata ; Female ; Fluconazole ; Humans |
| مستخلص: | Emphysematous pyelonephritis (EPN) is a rare acute necrotizing infection of the kidney and surrounding tissues, with gas in the renal parenchyma, collecting system or perirenal tissue. The bacterial etiology predominates; mainly Gram-negative bacilli; Candida spp. and C. albicans are rarely described. We describe a case of EPN caused by C. glabrata, sensitive to fluconazole in a young, hypertensive woman with undiagnosed diabetes mellitus (DM), with renal dysfunction upon admission; her abdominal CT scan found a volumetric increase in the left kidney, signs of gas collections and perirenal blurring. Despite the antimicrobial therapy instituted, due to clinical refractoriness, a double J catheter and subsequent total nephrectomy were indicated, with good postoperative evolution. Her uroculture showed C. glabrata sensitive to fluconazole, and the pathology study showed tubular atrophy and intense interstitial inflammatory infiltrate. Despite the serious, potentially fatal condition, we could control the infection and the patient recovered fully. Poor DM management is an important triggering factor, and it is of great relevance to identify the EPN through imaging exams due to the peculiarities of its clinical and potentially surgical management. |
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| المشرفين على المادة: | 8VZV102JFY (Fluconazole) |
| تواريخ الأحداث: | Date Created: 20210324 Date Completed: 20220929 Latest Revision: 20221014 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC9518622 |
| DOI: | 10.1590/2175-8239-JBN-2020-0184 |
| PMID: | 33760910 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2175-8239 |
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| DOI: | 10.1590/2175-8239-JBN-2020-0184 |