دورية أكاديمية
أعرض في EDS

18F-Fluorodeoxyglucose positron emission tomography computed tomography detection of single organ vasculitis of the breast: A case report.

التفاصيل البيبلوغرافية
العنوان: 18F-Fluorodeoxyglucose positron emission tomography computed tomography detection of single organ vasculitis of the breast: A case report.
المؤلفون: Harada T; Division of General Medicine, Showa University Koto Toyosu Hospital, Tokyo.; Division of Diagnostic and Generalist Medicine, Dokkyo Medical University Hospital, Tochigi., Sasaki Y; Department of General Medicine and Emergency Care, Toho University School of Medicine., Tokunaga T; Department of Rheumatology., Yoshizawa A; Department of Breast Surgery, Showa University Koto Toyosu Hospital., Miura S; Department of Diagnostic Pathology, NTT Medical Center.; Department of Pathology, Showa University School of Medicine, Tokyo., Ikeda K; Division of General Medicine, Showa University Koto Toyosu Hospital, Tokyo., Saito T; Department of Internal Medicine, Saitama Shinrin Hospital, Saitama, Japan., Hiroshige J; Division of General Medicine, Showa University Koto Toyosu Hospital, Tokyo.
المصدر: Medicine [Medicine (Baltimore)] 2021 Mar 26; Vol. 100 (12), pp. e25259.
نوع المنشور: Case Reports; Journal Article
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Hagerstown, Md : Lippincott Williams & Wilkins
مواضيع طبية MeSH: Breast*/blood supply , Breast*/diagnostic imaging , Mammary Arteries*/diagnostic imaging , Mammary Arteries*/pathology , Polyarteritis Nodosa*/diagnosis , Polyarteritis Nodosa*/physiopathology, Biopsy/*methods , Positron Emission Tomography Computed Tomography/*methods, Aged, 80 and over ; Diagnosis, Differential ; Female ; Fever/diagnosis ; Fever/etiology ; Fluorodeoxyglucose F18/pharmacology ; Humans ; Radiopharmaceuticals/pharmacology
مستخلص: Rationale: Although single organ vasculitis (SOV) is a rare occurrence and it is difficult to diagnose, its possibility as a cause of fever of unknown origin (FUO) must be considered. Recently, the usefulness of 18F-fluorodeoxyglucose positron emission tomography computed tomography (FDG PET/CT) in the diagnosis of unknown fevers due to vasculitis, especially in cases of small and medium-sized vasculitis, has begun to be pointed out.
Patient Concerns: We report the case of an 84-year-old woman with persisting fever for more than 2 weeks. She had no accompanying symptoms, other than fever, and the physical examination, echocardiography, and contrast-enhanced CT did not reveal any diagnostic clue.
Diagnoses: The FDG PET/CT revealed positive uptakes of FDG in the left breast, with a standardized uptake value (SUV) of 2.9. The biopsy specimen of the left breast lesion revealed rupture of the elastic plate and evidence of fibrinoid necrosis of arteries, leading to the diagnosis of polyarteritis (PAN). Further angiographic examination and additional imaging did not reveal the presence of other lesions. Therefore, the diagnosis was established as a PAN-SOV of the left breast.
Interventions: This patient has improved with follow-up only.
Outcomes: There has been no evidence of a relapse of PAN over a 5-year follow-up period.
Lessons: SOV presenting with unspecific local symptoms is difficult to diagnose based on the medical history and clinical examination. Our findings show that early "Combination of PET-CT and biopsy" can be a powerful diagnostic tool in patients with FUO for whom diagnosis of the underlying cause is difficult despite appropriate clinical examination.
Competing Interests: The authors have no funding and conflicts of interests to disclose.
(Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.)
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المشرفين على المادة: 0 (Radiopharmaceuticals)
0Z5B2CJX4D (Fluorodeoxyglucose F18)
تواريخ الأحداث: Date Created: 20210325 Date Completed: 20210405 Latest Revision: 20230103
رمز التحديث: 20230104
مُعرف محوري في PubMed: PMC9281965
DOI: 10.1097/MD.0000000000025259
PMID: 33761723
قاعدة البيانات: MEDLINE
الوصف
تدمد:1536-5964
DOI:10.1097/MD.0000000000025259