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Unrecognized Primary Hypothyroidism As a Possible Cause of Hyperreactio Luteinalis.

التفاصيل البيبلوغرافية
العنوان: Unrecognized Primary Hypothyroidism As a Possible Cause of Hyperreactio Luteinalis.
المؤلفون: Chauhan YV; Endocrinology, Topiwala National Medical College & Bai Yamunabai Laxman Nair Charitable Hospital, Mumbai, IND., Dalwadi PP; Endocrinology, Topiwala National Medical College & Bai Yamunabai Laxman Nair Charitable Hospital, Mumbai, IND., Gada JV; Endocrinology, Topiwala National Medical College & Bai Yamunabai Laxman Nair Charitable Hospital, Mumbai, IND., Varthakavi PK; Endocrinology, Topiwala National Medical College & Bai Yamunabai Laxman Nair Charitable Hospital, Mumbai, IND., Bhagwat N; Endocrinology, Topiwala National Medical College & Bai Yamunabai Laxman Nair Charitable Hospital, Mumbai, IND.
المصدر: Cureus [Cureus] 2021 Feb 26; Vol. 13 (2), pp. e13573. Date of Electronic Publication: 2021 Feb 26.
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: Electronic Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Palo Alto, CA : Cureus, Inc.
مستخلص: Hyperreactio luteinalis (HRL) is characterised by benign enlargement of ovaries in pregnancy associated with hyperandrogenism. A 19-year-old primigravida presented with breathlessness, abdominal distension and vomiting in the thirteenth week of gestation. Abdominal examination revealed distension of abdomen disproportionate to the gestational age. Ultrasound was suggestive of bilaterally enlarged multicystic ovaries with a characteristic "spoke-wheel" pattern and a diagnosis of HRL was made. Laboratory investigations revealed primary hypothyroidism and elevated testosterone. She was initiated on levothyroxine therapy. Her respiratory distress worsened on the third day of admission for which she underwent emergency laparotomy with cyst aspiration. Thyroid function tests normalized within six weeks after the initiation of therapy and remained normal for the remainder of pregnancy. Serum testosterone levels returned to normal six weeks postpartum. The elevated thyroid-stimulating hormone levels could have contributed to development of HRL by cross-reacting with human chorionic gonadotropin and follicle-stimulating hormone receptors. Hyperandrogenism and ovarian enlargement regresses with levothyroxine therapy.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2021, Chauhan et al.)
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فهرسة مساهمة: Keywords: fsh; hcg; hyperreactio luteinalis; hypothyroidism; pregnancy; spoke-wheel; tsh
تواريخ الأحداث: Date Created: 20210402 Latest Revision: 20210403
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC8005326
DOI: 10.7759/cureus.13573
PMID: 33796422
قاعدة البيانات: MEDLINE
الوصف
تدمد:2168-8184
DOI:10.7759/cureus.13573