دورية أكاديمية
Health-related quality of life in children and adolescents with epilepsy in Enugu: Need for targeted intervention.
| العنوان: | Health-related quality of life in children and adolescents with epilepsy in Enugu: Need for targeted intervention. |
|---|---|
| المؤلفون: | Aronu AE; Department of Paediatrics, College of Medicine, University of Nigeria Enugu Campus, Ituku-Ozalla, Nigeria., Uwaezuoke N; Department of Paediatrics, College of Medicine, University of Nigeria Enugu Campus, Ituku-Ozalla, Nigeria., Chinawa JM; Department of Paediatrics, College of Medicine, University of Nigeria Enugu Campus, Ituku-Ozalla, Nigeria., Bisi-Onyemaechi A; Department of Paediatrics, College of Medicine, University of Nigeria Enugu Campus, Ituku-Ozalla, Nigeria., Ojinnaka NC; Department of Paediatrics, College of Medicine, University of Nigeria Enugu Campus, Ituku-Ozalla, Nigeria. |
| المصدر: | Nigerian journal of clinical practice [Niger J Clin Pract] 2021 Apr; Vol. 24 (4), pp. 517-524. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Medknow Publications Country of Publication: India NLM ID: 101150032 Publication Model: Print Cited Medium: Internet ISSN: 1119-3077 (Print) NLM ISO Abbreviation: Niger J Clin Pract Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Mumbai : Medknow Publications Original Publication: [Lagos?] : Medical and Dental Consultants' Association of Nigeria |
| مواضيع طبية MeSH: | Epilepsy*/drug therapy , Epilepsy*/epidemiology , Quality of Life*, Adolescent ; Child ; Child, Preschool ; Cross-Sectional Studies ; Humans ; Nigeria ; Seizures ; Surveys and Questionnaires |
| مستخلص: | Background: Epilepsy, a chronic brain disorder, predisposes children to low Health-Related Quality of Life (HRQOL). Objective: This study aimed at assessing the HRQOL in Nigerian children with epilepsy and compare it with that in healthy children. Methods: A cross-sectional study of 166 children with epilepsy (CWE), aged 5-18 years on anti-epileptic drugs (AEDs) for at least 6 months and 166 age and sex-matched apparently healthy children was conducted. A generic version of the Pediatric Quality of Life (Peds QoL version 4) scale was used to assess HRQOL. Results: There were significant differences in Quality-of-Life mean scores in the domains of social functioning, psychosocial combination, and psychosocial plus physical activities between cases and controls. The school function scores of <50, indicating low QOL, were significantly more (Chi square = 35.37) (P = 0.0001) among the cases (32.5%) compared to the controls (6.3%). Similarly, low quality of life in the psychosocial combination were observed significantly (P_ = 0.042) more among the cases (12.7%) compared to the controls (6.3%). Low quality of life in emotional feeling domain were noted significantly (Chi square = 12.9) (P = 0.0002) more in subjects aged between 8 and 12 (20%). QOL scores of below 50 in the social function domain were observed significantly (Chi square = 6.49) (P = 0.039) more in subjects aged between 5 and 7 years (44.8%). There was significant gender difference in Quality-of-life index in school functioning domain in subjects. (Chi Square = 6.49) (P value = 0.039). Children in the upper social class scored higher in the social functioning domain, and social class was significantly associated with scores in the social domain of functioning. (F = 3.75 and P = 0.03). QOL scores below 50 in the emotional domain were significantly more among subjects aged 8-12 years/13-18 year, s and QOL scores of <50 in the school function domain were significantly more in subjects aged 5-7 years. (P = 0.0002) (P = 0.039), respectively. Conclusion: HRQOL is reduced in CWE in all domains of Peds QoL. Significant predictors of reduced HRQOL include age, gender, and socioeconomic class. Beyond seizure control, epilepsy management should be oriented towards ensuring the optimal health-related quality of life. Competing Interests: None |
| فهرسة مساهمة: | Keywords: Children; epilepsy; psychosocial functioning; quality of life |
| تواريخ الأحداث: | Date Created: 20210414 Date Completed: 20210415 Latest Revision: 20220422 |
| رمز التحديث: | 20221213 |
| DOI: | 10.4103/njcp.njcp_457_20 |
| PMID: | 33851673 |
| قاعدة البيانات: | MEDLINE |
كن أول من يترك تعليقا!