دورية أكاديمية
Understanding the patient journey to diagnosis of lung cancer.
| العنوان: | Understanding the patient journey to diagnosis of lung cancer. |
|---|---|
| المؤلفون: | Zhang Y; Department of Health Policy and Management, School of Public Health and Tropical Medicine, Tulane University, 1440 Canal Street, Suite 1900, New Orleans, LA, 70112, USA., Simoff MJ; Bronchoscopy and Interventional Pulmonology, Lung Cancer Screening Program, Pulmonary & Critical Care Medicine, Henry Ford Hospital, Wayne State University School of Medicine, 2799 West Grand Boulevard, Detroit, MI, 48202, USA. msimoff1@hfhs.org., Ost D; Department of Pulmonary Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Wagner OJ; Intuitive, 1020 Kifer Road, Sunnyvale, CA, 94086, USA., Lavin J; Intuitive, 1020 Kifer Road, Sunnyvale, CA, 94086, USA., Nauman B; Louisiana Public Health Institute, 1515 Poydras Street #1200, New Orleans, LA, 70112, USA., Hsieh MC; Louisiana State University Health Science Center, 433 Bolivar St, New Orleans, LA, 70112, USA., Wu XC; Louisiana State University Health Science Center, 433 Bolivar St, New Orleans, LA, 70112, USA., Pettiford B; Ochsner Health System, 1514 Jefferson Highway, Jefferson, LA, 70121, USA., Shi L; Department of Health Policy and Management, School of Public Health and Tropical Medicine, Tulane University, 1440 Canal Street, Suite 1900, New Orleans, LA, 70112, USA. |
| المصدر: | BMC cancer [BMC Cancer] 2021 Apr 14; Vol. 21 (1), pp. 402. Date of Electronic Publication: 2021 Apr 14. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : BioMed Central, [2001- |
| مواضيع طبية MeSH: | Critical Pathways* , Solitary Pulmonary Nodule*/diagnosis, Lung Neoplasms/*diagnosis , Lung Neoplasms/*epidemiology, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Ambulatory Care ; Biopsy ; Clinical Decision-Making ; Cohort Studies ; Disease Management ; Female ; Health Care Surveys ; Humans ; Lung Neoplasms/mortality ; Lung Neoplasms/therapy ; Male ; Middle Aged ; Neoplasm Staging ; Practice Patterns, Physicians' ; Registries ; SEER Program ; Young Adult |
| مستخلص: | Objective: This research describes the clinical pathway and characteristics of two cohorts of patients. The first cohort consists of patients with a confirmed diagnosis of lung cancer while the second consists of patients with a solitary pulmonary nodule (SPN) and no evidence of lung cancer. Linked data from an electronic medical record and the Louisiana Tumor Registry were used in this investigation. Materials and Methods: REACHnet is one of 9 clinical research networks (CRNs) in PCORnet®, the National Patient-Centered Clinical Research Network and includes electronic health records for over 8 million patients from multiple partner health systems. Data from Ochsner Health System and Tulane Medical Center were linked to Louisiana Tumor Registry (LTR), a statewide population-based cancer registry, for analysis of patient's clinical pathways between July 2013 and 2017. Patient characteristics and health services utilization rates by cancer stage were reported as frequency distributions. The Kaplan-Meier product limit method was used to estimate the time from index date to diagnosis by stage in lung cancer cohort. Results: A total of 30,559 potentially eligible patients were identified and 2929 (9.58%) had primary lung cancer. Of these, 1496 (51.1%) were documented in LTR and their clinical pathway to diagnosis was further studied. Time to diagnosis varied significantly by cancer stage. A total of 24,140 patients with an SPN were identified in REACHnet and 15,978 (66.6%) had documented follow up care for 1 year. 1612 (10%) had no evidence of any work up for their SPN. The remaining 14,366 had some evidence of follow up, primarily office visits and additional chest imaging. Conclusion: In both cohorts multiple biopsies were evident in the clinical pathway. Despite clinical workup, 70% of patients in the lung cancer cohort had stage III or IV disease. In the SPN cohort, only 66% were identified as receiving a diagnostic work-up. |
| References: | J Health Econ Outcomes Res. 2019 May 08;6(3):118-129. (PMID: 32685585) Chest. 2013 May;143(5 Suppl):e93S-e120S. (PMID: 23649456) Chest. 2005 Oct;128(4):2282-8. (PMID: 16236885) Lung. 2019 Apr;197(2):249-255. (PMID: 30783733) Clin Lung Cancer. 2006 Jan;7(4):268-72. (PMID: 16512981) N Engl J Med. 2020 Feb 6;382(6):503-513. (PMID: 31995683) J Am Med Inform Assoc. 2015 Sep;22(5):1072-80. (PMID: 26104741) Lung Cancer Manag. 2020 Aug 17;9(4):LMT40. (PMID: 33318758) J Thorac Oncol. 2009 Nov;4(11):1322-30. (PMID: 19752757) J Natl Cancer Inst. 1983 Apr;70(4):693-707. (PMID: 6572758) BMC Health Serv Res. 2019 Sep 18;19(1):679. (PMID: 31533705) Cancer Epidemiol. 2015 Dec;39(6):1136-44. (PMID: 26138902) Medicine (Baltimore). 2015 Jul;94(29):e1216. (PMID: 26200646) Ann Fam Med. 2020 May;18(3):196-201. (PMID: 32393553) N Engl J Med. 2011 Aug 4;365(5):395-409. (PMID: 21714641) Thorax. 1998 Jun;53 Suppl 1:S1-8. (PMID: 9713437) BMC Cancer. 2019 Jan 8;19(1):25. (PMID: 30621616) Ann Thorac Surg. 2017 Dec;104(6):1791-1797. (PMID: 29033012) J Thorac Oncol. 2006 Sep;1(7):692-6. (PMID: 17409938) Clinicoecon Outcomes Res. 2017 May 12;9:261-269. (PMID: 28553128) J Manag Care Spec Pharm. 2016 Oct;22(10):1194-203. (PMID: 27668568) Br J Cancer. 2011 Sep 27;105(7):1042-8. (PMID: 21897390) J Thorac Cardiovasc Surg. 2003 Jan;125(1):108-13; discussion 113-4. (PMID: 12538992) Thorax. 2009 Sep;64(9):749-56. (PMID: 19717709) J Thorac Dis. 2011 Sep;3(3):183-8. (PMID: 22263086) Transl Lung Cancer Res. 2015 Oct;4(5):503-14. (PMID: 26629419) Lung Cancer. 2011 Apr;72(1):125-31. (PMID: 20822826) South Med J. 2013 Oct;106(10):539-44. (PMID: 24096946) Br J Cancer. 2014 Oct 28;111(9):1843-51. (PMID: 25203519) |
| فهرسة مساهمة: | Keywords: Biopsy frequency; Bronchoscopy; Clinical pathway; Lung cancer; Pulmonary nodule; Staging |
| تواريخ الأحداث: | Date Created: 20210415 Date Completed: 20210510 Latest Revision: 20210510 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC8045203 |
| DOI: | 10.1186/s12885-021-08067-1 |
| PMID: | 33853552 |
| قاعدة البيانات: | MEDLINE |
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