دورية أكاديمية

Trends and predictors of HIV positivity and time since last test at voluntary counselling and testing encounters among adults in Kilifi, Kenya, 2006-2017.

التفاصيل البيبلوغرافية
العنوان: Trends and predictors of HIV positivity and time since last test at voluntary counselling and testing encounters among adults in Kilifi, Kenya, 2006-2017.
المؤلفون: Mugo PM; Kenya Medical Research Institute (KEMRI) -Wellcome Trust Research Programme, Kilifi, Kenya., Agutu CA; Kenya Medical Research Institute (KEMRI) -Wellcome Trust Research Programme, Kilifi, Kenya., Wahome E; Kenya Medical Research Institute (KEMRI) -Wellcome Trust Research Programme, Kilifi, Kenya., Juma M; Kenya Medical Research Institute (KEMRI) -Wellcome Trust Research Programme, Kilifi, Kenya., Nzioka J; Kenya Medical Research Institute (KEMRI) -Wellcome Trust Research Programme, Kilifi, Kenya., Mohamed K; Kenya Medical Research Institute (KEMRI) -Wellcome Trust Research Programme, Kilifi, Kenya., Mumba T; Kenya Medical Research Institute (KEMRI) -Wellcome Trust Research Programme, Kilifi, Kenya., Shally M; Kenya Medical Research Institute (KEMRI) -Wellcome Trust Research Programme, Kilifi, Kenya., Fauz I; Ministry of Health, Kilifi, Kenya., Omar A; Ministry of Health, Kilifi, Kenya., Rinke de Wit TF; Amsterdam Institute for Global Health and Development (AIGHD), Department of Global Health, University of Amsterdam, Amsterdam, The Netherlands., van der Elst EM; Kenya Medical Research Institute (KEMRI) -Wellcome Trust Research Programme, Kilifi, Kenya., Graham SM; Departments of Global Health, Medicine, and Epidemiology, University of Washington, Seattle, WA, USA., Sanders EJ; Kenya Medical Research Institute (KEMRI) -Wellcome Trust Research Programme, Kilifi, Kenya.; Amsterdam Institute for Global Health and Development (AIGHD), Department of Global Health, University of Amsterdam, Amsterdam, The Netherlands.; Nuffield Department of Medicine, University of Oxford, Headington, UK.
المصدر: Wellcome open research [Wellcome Open Res] 2021 Jun 04; Vol. 4, pp. 127. Date of Electronic Publication: 2021 Jun 04 (Print Publication: 2019).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wellcome Trust Country of Publication: England NLM ID: 101696457 Publication Model: eCollection Cited Medium: Print ISSN: 2398-502X (Print) Linking ISSN: 2398502X NLM ISO Abbreviation: Wellcome Open Res Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [London] : Wellcome Trust, [2016]-
مستخلص: Background: Little is known about HIV retesting uptake among key populations (KP) and general populations (GP) in Kenya. We assessed trends and predictors of first-time testing (FTT), late retesting (previous test more than one year ago for GP or three months for KP), and test positivity at three voluntary counselling and testing (VCT) centres in coastal Kenya. Methods : Routine VCT data covering 2006-2017 was collected from three VCT centres in Kilifi County. We analysed HIV testing history and test results from encounters among adults 18-39 years, categorized as GP men, GP women, men who have sex with men (MSM), and female sex workers (FSW).     Results: Based on 24,728 test encounters (32% FTT), we observed declines in HIV positivity (proportion of encounters where the result was positive) among GP men, GP women, first-time testers and MSM but not among FSW. The proportion of encounters for FTT and late retesting decreased for both GP and KP but remained much higher in KP than GP. HIV positivity was higher at FTT and late retesting encounters; at FSW and MSM encounters; and at encounters with clients reporting lower educational attainment and sexually transmitted infection (STI) symptoms. HIV positivity was lower in GP men, never married clients and those less than 35 years of age. FTT was associated with town, risk group, age 18-24 years, never-married status, low educational attainment, and STI symptoms. Late retesting was less common among encounters with GP individuals who were never married, had Muslim or no religious affiliation, had lower educational attainment, or reported STI symptoms. Conclusions: HIV positive test results were most common at encounters with first-time testers and late re-testers. While the proportion of encounters at which late retesting was reported decreased steadily over the period reviewed, efforts are needed to increase retesting among the most at-risk populations.
Competing Interests: No competing interests were disclosed.
(Copyright: © 2021 Mugo PM et al.)
References: AIDS. 2013 Jan 28;27(3):437-46. (PMID: 23079811)
J Int AIDS Soc. 2016 Dec 19;19(1):21348. (PMID: 27989271)
AIDS Behav. 2018 Aug;22(8):2435-2457. (PMID: 29464430)
AIDS. 2006 Jun 26;20(10):1447-50. (PMID: 16791020)
Sex Transm Infect. 2006 Apr;82 Suppl 1:i21-6. (PMID: 16581755)
Sex Transm Infect. 2013 Nov;89(7):583-9. (PMID: 23698510)
Ecology. 2014 Mar;95(3):609-10. (PMID: 24804440)
J Int AIDS Soc. 2018 Jul;21(7):e25164. (PMID: 29989338)
PLoS One. 2020 Jan 23;15(1):e0227741. (PMID: 31971991)
AIDS Behav. 2021 May 28;:. (PMID: 34046763)
J Acquir Immune Defic Syndr. 2008 Oct 1;49(2):183-9. (PMID: 18769350)
Clin Infect Dis. 2014 Jan;58(1):117-20. (PMID: 24092804)
Lancet. 2012 Jul 28;380(9839):424-38. (PMID: 22819663)
AIDS Behav. 2018 Jul;22(7):2368-2379. (PMID: 29779162)
Wellcome Open Res. 2019 Aug 23;4:127. (PMID: 33884308)
AIDS. 2010 Jul 17;24(11):1739-47. (PMID: 20588173)
AIDS. 2008 May 31;22(9):1071-7. (PMID: 18520351)
J Int AIDS Soc. 2017 Jul 18;20(1):21691. (PMID: 28782333)
J Int AIDS Soc. 2018 Apr;21(4):e25095. (PMID: 29652098)
AIDS. 2019 Dec 15;33 Suppl 3:S255-S269. (PMID: 31764066)
J Acquir Immune Defic Syndr. 2009 Jul 1;51(3):310-6. (PMID: 19582895)
AIDS Behav. 2018 Aug;22(8):2387-2412. (PMID: 29550941)
AIDS Care. 2007 May;19(5):692-6. (PMID: 17505932)
معلومات مُعتمدة: United Kingdom WT_ Wellcome Trust; P30 AI027757 United States AI NIAID NIH HHS; R01 AI124968 United States AI NIAID NIH HHS
فهرسة مساهمة: Keywords: HIV diagnosis; HIV retesting; Kenya; Kilifi County; Voluntary counselling and testing
تواريخ الأحداث: Date Created: 20210615 Latest Revision: 20240216
رمز التحديث: 20240216
مُعرف محوري في PubMed: PMC8042516.3
DOI: 10.12688/wellcomeopenres.15401.3
PMID: 33884308.3. Version: 3. Publisher Version ID: 3. Version Date: 2021/06/04
قاعدة البيانات: MEDLINE
الوصف
تدمد:2398-502X
DOI:10.12688/wellcomeopenres.15401.3