دورية أكاديمية
أعرض في EDS

Prevalence and profile of depressive mixed state in patients with autism spectrum disorder.

التفاصيل البيبلوغرافية
العنوان: Prevalence and profile of depressive mixed state in patients with autism spectrum disorder.
المؤلفون: Zamami Y; Department of Neuropsychiatry, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan., Shinzato H; Department of Neuropsychiatry, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan; Department of Psychiatry and Neurosciences, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan. Electronic address: hshin530@hiroshima-u.ac.jp., Kurihara K; Department of Neuropsychiatry, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan., Koda M; Department of Neuropsychiatry, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan; Graduate School of Technology, Industrial and Social Sciences, Tokushima University, Japan., Nakamura A; Department of Neuropsychiatry, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan; Department of Psychiatry, Akari Clinic, Okinawa, Japan., Kondo T; Department of Neuropsychiatry, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
المصدر: Psychiatry research [Psychiatry Res] 2021 Jun; Vol. 300, pp. 113932. Date of Electronic Publication: 2021 Apr 19.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Ireland NLM ID: 7911385 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7123 (Electronic) Linking ISSN: 01651781 NLM ISO Abbreviation: Psychiatry Res Subsets: MEDLINE
أسماء مطبوعة: Publication: Limerick : Elsevier/North-Holland Biomedical Press
Original Publication: Amsterdam, Elsevier/North-Holland Biomedical Press.
مواضيع طبية MeSH: Autism Spectrum Disorder*/complications , Autism Spectrum Disorder*/epidemiology , Bipolar Disorder*/diagnosis , Depressive Disorder, Major*/diagnosis , Depressive Disorder, Major*/epidemiology, Diagnosis, Differential ; Humans ; Prevalence
مستخلص: Purpose: The present study aimed to clarify prevalence and profile of depressive mixed state (DMX) in depressed individuals with autism spectrum disorder (ASD).
Patients and Methods: The Quick Inventory of Depressive Symptomatology Self-Report Japanese version (QIDS-SR-J) and global assessment of functioning (GAF) were administered to 182 consecutive patients (36 ASD and 146 non-ASD subjects) with a major depressive episode (MDE). DMX was categorically diagnosed according to the criteria for mixed depression (MD) by Benazzi and mixed features (MF) specifier by DSM-5. Severity of DMX was assessed by the self-administered 12-item questionnaire for DMX (DMX-12). Clinical backgrounds and incidence/severity of DMX were compared between the ASD and non-ASD groups.
Results: ASD patients showed higher prevalence of MD than non-ASD patients (36.1% versus 18.5%). Mood lability, distractibility, impulsivity, aggression, irritability, dysphoria and risk-taking behavior as mixed symptoms were more prevalent in ASD patients than those in non-ASD patients, together with higher scores of total DMX-12 and its disruptive emotion/behavior cluster. Multiple regression analysis revealed significant contribution of ASD to the disruptive emotion/behavior symptoms.
Conclusion: Careful monitoring and management of potential DMX are warranted in depressed ASD individuals.
(Copyright © 2021. Published by Elsevier B.V.)
فهرسة مساهمة: Keywords: Autism spectrum disorders; Bipolarity; Major depressive episode; Mixed depression; Mixed features specifier
تواريخ الأحداث: Date Created: 20210422 Date Completed: 20210927 Latest Revision: 20210927
رمز التحديث: 20240829
DOI: 10.1016/j.psychres.2021.113932
PMID: 33887519
قاعدة البيانات: MEDLINE
الوصف
تدمد:1872-7123
DOI:10.1016/j.psychres.2021.113932