دورية أكاديمية
Host-microbial interactions in the metabolism of different dietary fats.
| العنوان: | Host-microbial interactions in the metabolism of different dietary fats. |
|---|---|
| المؤلفون: | Chadaideh KS; Department of Human Evolutionary Biology, Harvard University, 11 Divinity Avenue, Cambridge, MA 02138, USA., Carmody RN; Department of Human Evolutionary Biology, Harvard University, 11 Divinity Avenue, Cambridge, MA 02138, USA. Electronic address: carmody@fas.harvard.edu. |
| المصدر: | Cell metabolism [Cell Metab] 2021 May 04; Vol. 33 (5), pp. 857-872. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Cambridge, Mass. : Cell Press, c2005- |
| مواضيع طبية MeSH: | Gastrointestinal Microbiome*, Dietary Fats/*metabolism , Host Microbial Interactions/*physiology, Animals ; Bile Acids and Salts/metabolism ; Colon/microbiology ; Energy Metabolism ; Fatty Acids/metabolism ; Humans ; Intestine, Small/metabolism |
| مستخلص: | Although generally presumed to be isocaloric, dietary fats can differ in their energetic contributions and metabolic effects. Here, we show how an explicit consideration of the gut microbiome and its interactions with human physiology can enrich our understanding of dietary fat metabolism. We outline how variable human metabolic responses to different dietary fats, such as altered ileal digestibility or bile acid production, have downstream effects on the gut microbiome that differentially promote energy gain and inflammation. By incorporating host-microbial interactions into energetic models of human nutrition, we can achieve greater insight into the underlying mechanisms of diet-driven metabolic disease. Competing Interests: Declaration of interests The authors declare no competing interests. (Copyright © 2021 Elsevier Inc. All rights reserved.) |
| المشرفين على المادة: | 0 (Bile Acids and Salts) 0 (Dietary Fats) 0 (Fatty Acids) |
| تواريخ الأحداث: | Date Created: 20210505 Date Completed: 20220222 Latest Revision: 20220222 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.cmet.2021.04.011 |
| PMID: | 33951472 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1932-7420 |
|---|---|
| DOI: | 10.1016/j.cmet.2021.04.011 |