دورية أكاديمية
أعرض في EDS

Physical Functioning in Heart Failure With Preserved Ejection Fraction.

التفاصيل البيبلوغرافية
العنوان: Physical Functioning in Heart Failure With Preserved Ejection Fraction.
المؤلفون: Cosiano MF; Department of Internal Medicine., Tobin R; Department of Internal Medicine., Mentz RJ; Division of Cardiology, Duke University School of Medicine; Duke Clinical Research Institute, Durham, North Carolina., Greene SJ; Division of Cardiology, Duke University School of Medicine; Duke Clinical Research Institute, Durham, North Carolina. Electronic address: stephen.greene@duke.edu.
المصدر: Journal of cardiac failure [J Card Fail] 2021 Sep; Vol. 27 (9), pp. 1002-1016. Date of Electronic Publication: 2021 May 12.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Churchill Livingstone Country of Publication: United States NLM ID: 9442138 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8414 (Electronic) Linking ISSN: 10719164 NLM ISO Abbreviation: J Card Fail Subsets: MEDLINE
أسماء مطبوعة: Publication: <2002->: Philadelphia, PA : Churchill Livingstone
Original Publication: Naperville, IL : Churchill Livingstone, c1994-
مواضيع طبية MeSH: Heart Failure*/diagnosis , Heart Failure*/epidemiology , Heart Failure*/therapy, Comorbidity ; Humans ; Patient Reported Outcome Measures ; Prognosis ; Stroke Volume
مستخلص: Heart failure with preserved ejection fraction (HFpEF) is increasingly prevalent, yet interventions and therapies to improve outcomes remain limited. There has been increasing attention towards the impact of comorbidities and physical functioning (PF) on poor clinical outcomes within this population. In this review, we summarize and discuss the literature on PF in HFpEF, its association with clinical and patient-centered outcomes, and future advances in the care of HFpEF with respect to PF. Multiple PF metrics have been demonstrated to provide prognostic value within HFpEF, yet the data are less robust compared with other patient populations, highlighting the need for further investigation. The evaluation and detection of poor PF provides a potential strategy to improve care in HFpEF, and future studies are needed to understand if modulating PF improves clinical and/or patient-reported outcomes. LAY SUMMARY: • Patients with heart failure with preserved ejection fraction (HFpEF) commonly have impaired physical functioning (PF) demonstrated by limitations across a wide range of common PF metrics.• Impaired PF metrics demonstrate prognostic value for both clinical and patient-reported outcomes in HFpEF, making them plausible therapeutic targets to improve outcomes.• Clinical trials are ongoing to investigate novel methods of detecting, monitoring, and improving impaired PF to enhance HFpEF care.Heart failure with preserved ejection fraction (HFpEF) is increasingly prevalent, yet interventions and therapies to improve outcomes remain limited. As such, there has been increasing focus on the impact of physical performance (PF) on clinical and patient-centered outcomes. In this review, we discuss the state of PF in patients with HFpEF by examining the multitude of PF metrics available, their respective strengths and limitations, and their associations with outcomes in HFpEF. We highlight future advances in the care of HFpEF with respect to PF, particularly regarding the evaluation and detection of poor PF.
(Copyright © 2021 Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: HFpEF; Physical functioning; quality of life
تواريخ الأحداث: Date Created: 20210515 Date Completed: 20211119 Latest Revision: 20211119
رمز التحديث: 20221213
DOI: 10.1016/j.cardfail.2021.04.013
PMID: 33991684
قاعدة البيانات: MEDLINE
الوصف
تدمد:1532-8414
DOI:10.1016/j.cardfail.2021.04.013