دورية أكاديمية
Maternal Vitamin D Levels and Its Correlation With Low Birth Weight in Neonates: A Tertiary Care Hospital Experience in Saudi Arabia.
| العنوان: | Maternal Vitamin D Levels and Its Correlation With Low Birth Weight in Neonates: A Tertiary Care Hospital Experience in Saudi Arabia. |
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| المؤلفون: | Almidani E; Pediatrics, King Faisal Specialist Hospital and Research Centre, Riyadh, SAU., Barkoumi A; Pediatrics, Alfaisal University College of Medicine, Riyadh, SAU., Elsaidawi W; Pediatrics, King Faisal Specialist Hospital and Research Centre, Riyadh, SAU., Al Aliyan S; Pediatrics, King Faisal Specialist Hospital and Research Centre, Riyadh, SAU., Kattan A; Pediatrics, King Faisal Specialist Hospital and Research Centre, Riyadh, SAU., Alhazzani F; Pediatrics, King Faisal Specialist Hospital and Research Centre, Riyadh, SAU., Bin Jabr M; Pediatrics, King Faisal Specialist Hospital and Research Centre, Riyadh, SAU., Binmanee A; Pediatrics, King Faisal Specialist Hospital and Research Centre, Riyadh, SAU., Alsahan N; Obstetrics and Gynaecology, King Faisal Specialist Hospital and Research Centre, Riyadh, SAU., Alazmeh S; Medicine, Alfaisal University College of Medicine, Riyadh, SAU. |
| المصدر: | Cureus [Cureus] 2021 Apr 16; Vol. 13 (4), pp. e14528. Date of Electronic Publication: 2021 Apr 16. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: Electronic Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Palo Alto, CA : Cureus, Inc. |
| مستخلص: | Introduction A meta-analysis showed that 63.6% of the Saudi population have vitamin D deficiency, including many pregnant women. Studies showed that maternal vitamin D deficiency during pregnancy is a risk factor for low birth weight (LBW) in neonates. Neonatal LBW is a risk factor for multiple neonatal complications including respiratory distress syndrome, necrotizing enterocolitis, chronic renal disorders, seizures, and sepsis. Our objective in this study is to determine a correlation between low maternal vitamin D level and neonatal LBW in Saudi Arabia. Methods Neonates (n = 119) were divided based on their gestational age (GA) into full-term neonates (≥37 weeks) and preterm neonates (< 37 weeks) and based on birth weight into normal birth weight neonates (full-term = 2,500-3,500 g or preterm > 10th percentile) and LBW neonates (full-term < 2,500 g or preterm < 10th percentile). Vitamin D deficiency is defined as 25- hydroxyvitamin D level less than 50 nmol/L. Results Correlating neonatal birth weight with maternal vitamin D level during pregnancy was statistically insignificant for both full-term neonates and preterm neonates. In contrast, comparing the mean maternal vitamin D levels in each neonatal group showed that the mean were higher in mothers of neonates with normal birth weight. Conclusion Because 87.4% of mothers had low vitamin D levels during their pregnancy, correlation between maternal vitamin D level and LBW in neonates could not be found. However, mean maternal vitamin D levels were higher in mothers with normal birth weight neonates. Therefore, further detailed studies are required to establish local guidelines about the treatment of vitamin D deficiency during pregnancy. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2021, Almidani et al.) |
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| فهرسة مساهمة: | Keywords: birth weight; low birth weight; maternal-child health; neonatal intensive care unit (nicu); pediatrics & neonatology; preterm neonate; public awareness of vitamin d; saudi arabia; term neonates; vitamin d |
| تواريخ الأحداث: | Date Created: 20210520 Latest Revision: 20210522 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC8126481 |
| DOI: | 10.7759/cureus.14528 |
| PMID: | 34012736 |
| قاعدة البيانات: | MEDLINE |
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