دورية أكاديمية
Effects of mancozeb on heat Shock protein 70 (HSP70) and its relationship with the thermal physiology of Physalaemus henselii (Peters, 1872) tadpoles (Anura: Leptodactylidae).
| العنوان: | Effects of mancozeb on heat Shock protein 70 (HSP70) and its relationship with the thermal physiology of Physalaemus henselii (Peters, 1872) tadpoles (Anura: Leptodactylidae). |
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| المؤلفون: | Azambuja G; Universidade Federal de Santa Maria,Av. Roraima, Nº 1000, Santa Maria, RS, Brazil. Electronic address: guilhermeazambs@hotmail.com., Martins IK; Universidade Federal do Pampa, Campus São Gabriel, RS, Brazil., Franco JL; Universidade Federal do Pampa, Campus São Gabriel, RS, Brazil., Dos Santos TG; Universidade Federal do Pampa, Campus São Gabriel, RS, Brazil. |
| المصدر: | Journal of thermal biology [J Therm Biol] 2021 May; Vol. 98, pp. 102911. Date of Electronic Publication: 2021 Mar 23. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Pergamon Press Country of Publication: England NLM ID: 7600115 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0306-4565 (Print) Linking ISSN: 03064565 NLM ISO Abbreviation: J Therm Biol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Oxford, New York, Pergamon Press. |
| مواضيع طبية MeSH: | Anura/*physiology , Fungicides, Industrial/*toxicity , HSP70 Heat-Shock Proteins/*physiology , Maneb/*toxicity , Reptilian Proteins/*physiology , Thermotolerance/*drug effects , Zineb/*toxicity, Animals ; Larva/drug effects ; Larva/physiology |
| مستخلص: | Negative impacts on amphibians have been reported due to contamination by agrochemicals. However, until now, no study has tested the effect of the fungicide mancozeb (MZ) on thermal tolerance and its relationship with the expression of heat shock proteins (HSPs). MZ is the best-selling broad-spectrum fungicide in the world, which negatively affects non-target organisms. Here, we tested for the first time the effects of MZ on critical thermal maximum (CTmax) and its relationship to the expression of heat shock protein 70 (HSP70) in tadpoles of Physalameus henselii, a colder-adapted species in southernmost of the Neotropical region. A sublethal concentration of 2 mg/L was used. We found that the CTmax of the MZ-treated group was lower than that of the control group. In addition, there was an increase in HSP70 expression in tadpoles exposed to MZ and in tadpoles that underwent heat treatment. However, tadpoles subjected to MZ and heat treatment showed no induced HSP70 protein expression. Our results demonstrated that sublethal doses of the fungicide MZ negatively affected the thermal physiology and heat shock protein expression in tadpoles of P. henselii by inducing an increase in HSP70 concentration and by reducing the critical CTmax supported by tadpoles. It is important to understand the relationship between environmental contamination and physiological thermal limits in our current scenario of high rates of habitat conversion associated with unrestricted use of agrochemicals, as well as the challenging environmental changes induced by global warming. (Copyright © 2021 Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Agrochemical contamination; CTmax; Ecotoxicity; Neotropical anuran; Thermal tolerance |
| المشرفين على المادة: | 0 (Fungicides, Industrial) 0 (HSP70 Heat-Shock Proteins) 0 (Reptilian Proteins) 12427-38-2 (Maneb) R0HY55EB9E (mancozeb) X1FSB1OZPT (Zineb) |
| تواريخ الأحداث: | Date Created: 20210521 Date Completed: 20211203 Latest Revision: 20211214 |
| رمز التحديث: | 20240829 |
| DOI: | 10.1016/j.jtherbio.2021.102911 |
| PMID: | 34016338 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0306-4565 |
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| DOI: | 10.1016/j.jtherbio.2021.102911 |