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Full autopsy in a confirmed COVID-19 patient in Lagos, Nigeria - A case report.

التفاصيل البيبلوغرافية
العنوان: Full autopsy in a confirmed COVID-19 patient in Lagos, Nigeria - A case report.
المؤلفون: Keshinro SO; Nigeria Police Force, Nigeria Police Medical Services, Police Hospital, Falomo, Ikoyi, Lagos, Nigeria., Awolola NA; Anatomic and Molecular Pathology Department, LUTH, Idi-Araba, Lagos, Nigeria., Adebayo LA; Anatomic and Molecular Pathology Department, LUTH, Idi-Araba, Lagos, Nigeria., Mutiu WB; Lagos State Biobank, Directorate of Epidemiology, Biosecurity & Global Health, Ministry of Health, Lagos State, Nigeria., Saka BA; Lagos State Biobank, Directorate of Epidemiology, Biosecurity & Global Health, Ministry of Health, Lagos State, Nigeria., Abdus-Salam IA; Directorate of Epidemiology, Biosecurity & Global Health, Ministry of Health, Lagos State, Nigeria.
المصدر: Human pathology (New York) [Hum Pathol (N Y)] 2021 Jun; Vol. 24, pp. 200524. Date of Electronic Publication: 2021 May 16.
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101678095 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2214-3300 (Print) Linking ISSN: 22143300 NLM ISO Abbreviation: Hum Pathol (N Y) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [New York] : Elsevier Inc., [2014]-[2021]
مستخلص: Objectives: To report the postmortem findings of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive individual who died in Lagos (Nigeria) in June 2020 and to investigate the cause, pathogenesis as well as pathological changes noticed during the examination.
Methods: Complete postmortem examination was performed according to standard procedures in a regular autopsy suite using personal protective equipment including N95 masks, goggles and disposable gowns. The diagnosis of coronavirus disease 2019 (COVID-19) was confirmed by real-time reverse transcription polymerase chain reaction (RT-PCR) testing on postmortem nasopharyngeal swabs.
Results: A 47-year-old man with a medical history of well controlled hypertension and dyslipidaemia died after long hours of transportation for medical care in a hospital in Lagos. He tested positive for SARS-CoV-2 on ante- and postmortem nasopharyngeal swabs. Autopsy revealed pneumonia with diffuse alveolar damage, disseminated intravascular coagulopathy and hypovolaemic shock.
Conclusions: Autopsy can be performed on decedents who died from or with SARS-CoV-2 infection in a low resource environment such as ours. A standard autopsy room was used while deploying recommended infection prevention control and regular decontamination. The clinical details, autopsy findings such as diffuse alveolar damage and airway inflammation were consistent with a COVID-19 related pathology. While the decedent had 'controlled' co-morbidity, he succumbed to multi-organ failure occasioned by shock and disseminated intravascular coagulopathy.
Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(© 2021 The Author(s).)
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فهرسة مساهمة: Keywords: COVID-19; Diffuse alveolar damage; Disseminated intravascular; Post-mortem
تواريخ الأحداث: Date Created: 20210524 Latest Revision: 20221028
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC8125910
DOI: 10.1016/j.ehpc.2021.200524
PMID: 34026549
قاعدة البيانات: MEDLINE
الوصف
تدمد:2214-3300
DOI:10.1016/j.ehpc.2021.200524