دورية أكاديمية
High frequency ultrasonography: reliable tool to measure skin fibrosis in SSC? A systematic literature review and additional pilot study.
| العنوان: | High frequency ultrasonography: reliable tool to measure skin fibrosis in SSC? A systematic literature review and additional pilot study. |
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| المؤلفون: | Vanhaecke A; Department of Internal Medicine, Ghent University, Ghent, Belgium.; Department of Rheumatology, Ghent University Hospital, Ghent, Belgium., Cutolo M; Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genoa, IRCCS San Martino Polyclinic Hospital, Genoa, Italy., Heeman L; Department of Internal Medicine, Ghent University, Ghent, Belgium.; Department of Rheumatology, Ghent University Hospital, Ghent, Belgium., Vilela V; Department of Rheumatology, Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, RJ, Brazil., Deschepper E; Biostatistics Unit, Department of Public Health and Primary Care, Ghent University, Ghent, Belgium., Melsens K; Department of Internal Medicine, Ghent University, Ghent, Belgium.; Department of Rheumatology, Ghent University Hospital, Ghent, Belgium., Smith V; Department of Internal Medicine, Ghent University, Ghent, Belgium.; Department of Rheumatology, Ghent University Hospital, Ghent, Belgium.; Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Centre (IRC), Ghent, Belgium. |
| المصدر: | Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2021 Dec 24; Vol. 61 (1), pp. 42-52. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Systematic Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 100883501 Publication Model: Print Cited Medium: Internet ISSN: 1462-0332 (Electronic) Linking ISSN: 14620324 NLM ISO Abbreviation: Rheumatology (Oxford) Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Oxford, UK : Avenel, N.J. : Oxford University Press ; Distributed by Mercury International, c1999- |
| مواضيع طبية MeSH: | Scleroderma, Systemic/*diagnostic imaging , Skin/*diagnostic imaging, Adult ; Aged ; Female ; Fibrosis ; Humans ; Male ; Middle Aged ; Pilot Projects ; Reproducibility of Results ; Ultrasonography |
| مستخلص: | Objectives: To investigate the reliability of high frequency ultrasound (HFUS) in measuring skin fibrosis in SSc. Methods: First, a systematic review (according to PRISMA) was conducted to identify studies that documented HFUS' reliability in SSc as a primary outcome. Then, in an additional pilot study, the inter- and intra-rater reliability of two investigators performing HFUS for dermal thickness (DT) measurements in a standardized manner across all 17 areas of the modified Rodnan Skin Score was evaluated in a group of 59 SSc patients and descriptively in 44 healthy controls (HC). As an external validation, DT measurements by HFUS were performed in a separate group of 30 SSc patients by the same first and another third investigator. Results: The systematic review retained few (4/1719 unique records) small-scale studies, with mixed study populations (combining SSc and HC). The reported data herein are suggestive of the inter-/intra-rater reliability of HFUS (intra-class correlation coefficient [ICCs] ranging 0.65-0.94/0.55-0.96, respectively). Additionally, in our pilot study, inter-/intra-rater reliability was good-to-excellent in both SSc groups and HC (ICCs ranging 0.70-0.97/0.70-0.98 and 0.65-0.95/0.63-0.96, respectively). Conclusion: The identified small-scale studies were not only combining data from SSc and HC, they were also heterogeneous in terms of technical aspects (probes and frequency), image acquisition methods ([number of] areas assessed) and definitions used for skin thickness, which prevents drawing unequivocal conclusions. Despite these limitations, our standardized pilot study corroborated the findings in literature, paving the way for the applicability of HFUS as a reliable (complementary) tool to quantify skin fibrosis in SSc. (© The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: journals.permissions@oup.com.) |
| فهرسة مساهمة: | Keywords: reliability; skin fibrosis; systematic literature review; systemic sclerosis; ultrasound |
| تواريخ الأحداث: | Date Created: 20210526 Date Completed: 20220221 Latest Revision: 20220221 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1093/rheumatology/keab462 |
| PMID: | 34037710 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1462-0332 |
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| DOI: | 10.1093/rheumatology/keab462 |