دورية أكاديمية
Outcomes After Laparoscopic Cholecystectomy in Hyperkinetic Biliary Dyskinesia.
| العنوان: | Outcomes After Laparoscopic Cholecystectomy in Hyperkinetic Biliary Dyskinesia. |
|---|---|
| المؤلفون: | Whitaker LF; Department of General Surgery, 12279Wake Forest School of Medicine, Winston Salem, NC, USA., Bosley ME; Department of General Surgery, 12279Wake Forest School of Medicine, Winston Salem, NC, USA., Refugia JM; Department of General Surgery, 12279Wake Forest School of Medicine, Winston Salem, NC, USA., Powell MS; Department of General Surgery, 12279Wake Forest School of Medicine, Winston Salem, NC, USA., McNatt SS; Department of General Surgery, 12279Wake Forest School of Medicine, Winston Salem, NC, USA., Westcott CJ; Department of General Surgery, 12279Wake Forest School of Medicine, Winston Salem, NC, USA., Koch KL; Department of Gastroenterology, 12279Wake Forest School of Medicine, Winston Salem, NC, USA., Bennett P; Department of Radiology, 12279Wake Forest School of Medicine, Winston Salem, NC, USA., Rigdon J; Department Biostatistics and Data Science, 12279Wake Forest School of Medicine, Winston Salem, NC, USA., Fernandez AZ; Department of General Surgery, 12279Wake Forest School of Medicine, Winston Salem, NC, USA. |
| المصدر: | The American surgeon [Am Surg] 2022 Aug; Vol. 88 (8), pp. 1983-1987. Date of Electronic Publication: 2021 May 28. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: SAGE Publications in association with Southeastern Surgical Congress Country of Publication: United States NLM ID: 0370522 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1555-9823 (Electronic) Linking ISSN: 00031348 NLM ISO Abbreviation: Am Surg Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2020- : [Thousand Oaks, CA] : SAGE Publications in association with Southeastern Surgical Congress Original Publication: Atlanta Ga : Southeastern Surgical Congress |
| مواضيع طبية MeSH: | Biliary Dyskinesia*/complications , Biliary Dyskinesia*/diagnosis , Biliary Dyskinesia*/surgery , Cholecystectomy, Laparoscopic*/adverse effects , Cholecystectomy, Laparoscopic*/methods, Abdominal Pain/surgery ; Humans ; Retrospective Studies ; Treatment Outcome |
| مستخلص: | Background: Biliary dyskinesia (BD) is a poorly understood functional gallbladder disorder. Diagnosis is made with abdominal pain and an intact gallbladder without signs of anatomical obstruction on imaging or pathology. Our aim was to assess whether laparoscopic cholecystectomy (LC) resolves hyperkinetic BD symptoms. Methods: Records of patients ≥18 years of age, who underwent LC by four surgeons at a tertiary care center between 2012 and 2020, were retrospectively reviewed. Patients were excluded if they had a documented gallbladder ejection fraction (GBEF) <80% or had biliary stones or sludge on pathology or imaging. Demographic information, HIDA results, preoperative testing, operative details, gallbladder pathology, and symptom status at follow-up were collected from electronic medical records. Improvement in BD symptoms was assessed using McNemar's test. Risk differences with standard errors were employed to estimate percent reduction in symptoms. Results: Ninety-eight patients met inclusion criteria. Of those who presented for follow-up (n = 91), 92.3% (n = 84) reported partial or complete resolution of symptoms. Preoperative symptoms, including back pain (16.7%, 95% CI: [7.9%, 25.5%]; P < .0001), epigastric pain (31.1% [21.3%, 41.3%]; P < .0001), nausea (56.7% [45.0%, 65.8%]; P < .0001), RUQ pain (57.8% [46.1%, 66.9%]; P < .0001), and vomiting (27.8% [18.4%, 37.7%]; P < .0001) showed significant improvement after LC. Chronic cholecystitis and/or cholesterolosis were present on pathology in 79.8% of gallbladders. Discussion: Our study currently represents the largest cohort of patients with hyperkinetic BD. Laparoscopic cholecystectomy appears to result in resolution of symptoms for this clinical entity. |
| فهرسة مساهمة: | Keywords: biliary; dyskinesia; general surgery; hyperkinetic biliary; laparoscopic cholecystectomy; minimally invasive surgery |
| تواريخ الأحداث: | Date Created: 20210529 Date Completed: 20220713 Latest Revision: 20220713 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1177/00031348211023390 |
| PMID: | 34049442 |
| قاعدة البيانات: | MEDLINE |
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