دورية أكاديمية
The effect of a transitional pharmaceutical care program on the occurrence of ADEs after discharge from hospital in patients with polypharmacy.
| العنوان: | The effect of a transitional pharmaceutical care program on the occurrence of ADEs after discharge from hospital in patients with polypharmacy. |
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| المؤلفون: | Uitvlugt EB; Department of Clinical Pharmacy, Jan Tooropstraat 164, 1061AE, Amsterdam, the Netherlands. Electronic address: e.uitvlugt@olvg.nl., Heer SE; Department of Clinical Pharmacology and Pharmacy, De Boelelaan 1117, 1081, HV, Amsterdam, the Netherlands. Electronic address: s.en-nasery@amsterdamumc.nl., van den Bemt BJF; Department of Pharmacy, Sint Maartenskliniek, Nijmegen, The Netherlands. Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands. Electronic address: b.vandenbemt@maartenskliniek.nl., Bet PM; Department of Clinical Pharmacology and Pharmacy, De Boelelaan 1117, 1081, HV, Amsterdam, the Netherlands. Electronic address: pm.bet@amsterdamumc.nl., Sombogaard F; Department of Clinical Pharmacology and Pharmacy, De Boelelaan 1117, 1081, HV, Amsterdam, the Netherlands. Electronic address: f.sombogaard@amsterdamumc.nl., Hugtenburg JG; Department of Clinical Pharmacology and Pharmacy, De Boelelaan 1117, 1081, HV, Amsterdam, the Netherlands. Electronic address: jg.hugtenburg@amsterdamumc.nl., van den Bemt PMLA; University Medical Center Rotterdam, Department of Hospital Pharmacy. University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, the Netherlands. Electronic address: m.l.a.van.den.bemt@umcg.nl., Karapinar-Çarkit F; Department of Clinical Pharmacy, Jan Tooropstraat 164, 1061AE, Amsterdam, the Netherlands. Electronic address: f.karapinar@olvg.nl. |
| المصدر: | Research in social & administrative pharmacy : RSAP [Res Social Adm Pharm] 2022 Apr; Vol. 18 (4), pp. 2651-2658. Date of Electronic Publication: 2021 May 21. |
| نوع المنشور: | Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 101231974 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1934-8150 (Electronic) Linking ISSN: 15517411 NLM ISO Abbreviation: Res Social Adm Pharm Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: New York, NY : Elsevier |
| مواضيع طبية MeSH: | Drug-Related Side Effects and Adverse Reactions*/prevention & control , Pharmaceutical Services* , Pharmacy* , Transitional Care*, Aftercare ; Hospitals, Teaching ; Humans ; Medication Errors ; Medication Reconciliation ; Patient Discharge ; Pharmacists ; Polypharmacy ; Prospective Studies |
| مستخلص: | Introduction: Transitional care programs (i.e. interventions delivered both in hospital and in primary care), could increase continuity and consequently quality of care. However, limited studies on the effect of these programs on Adverse Drug Events (ADEs) post-discharge are available. Therefore, the aim of this study was to investigate the effect of a transitional pharmaceutical care program on the occurrence of ADEs 4 weeks post-discharge. Methods: A multicentre prospective before-after study was performed in a general teaching hospital, a university hospital and 49 community pharmacies. The transitional pharmaceutical care program consisted of: teach-back to the patient at discharge, a pharmaceutical discharge letter, a home visit by a community pharmacist and a clinical medication review by both the community and the clinical pharmacist, on top of usual care. Usual care consisted of medication reconciliation at admission and discharge by pharmacy teams. The primary outcome was the proportion of patients who reported at least 1 ADE 4 weeks post-discharge. Multivariable logistic regression was used to adjust for potential confounders. Results: In total, 369 patients were included (control: n = 195, intervention: n = 174). The proportion of patients with at least 1 ADE did not statistically significant differ between the intervention and control group (general teaching hospital: 59% vs. 67%, OR Conclusion: The transitional pharmaceutical care program did not decrease the proportion of patients with ADEs after discharge. ADEs after discharge were common and more than 50% of patients reported at least 1 ADE. A process evaluation is needed to gain insight into how a transitional pharmaceutical care program could diminish those ADEs. (Copyright © 2021. Published by Elsevier Inc.) |
| فهرسة مساهمة: | Keywords: Adverse drug events; Hospital discharge; Medication reconciliation |
| سلسلة جزيئية: | NTR NL7788 |
| تواريخ الأحداث: | Date Created: 20210529 Date Completed: 20220328 Latest Revision: 20220531 |
| رمز التحديث: | 20240829 |
| DOI: | 10.1016/j.sapharm.2021.05.009 |
| PMID: | 34049802 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1934-8150 |
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| DOI: | 10.1016/j.sapharm.2021.05.009 |