دورية أكاديمية
أعرض في EDS

Effect of Antibacterial Root Canal Sealer on Persistent Apical Periodontitis.

التفاصيل البيبلوغرافية
العنوان: Effect of Antibacterial Root Canal Sealer on Persistent Apical Periodontitis.
المؤلفون: Wang Z; State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu 610041, China., Yang G; State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu 610041, China., Ren B; State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu 610041, China., Gao Y; State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu 610041, China., Peng X; State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu 610041, China., Li M; State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu 610041, China., H K Xu H; Department of Advanced Oral Sciences and Therapeutics, Biomaterials & Tissue Engineering Division, School of Dentistry, University of Maryland, Baltimore, MD 21201, USA., Han Q; State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu 610041, China., Li J; State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu 610041, China., Zhou X; State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu 610041, China., Cheng L; State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu 610041, China.
المصدر: Antibiotics (Basel, Switzerland) [Antibiotics (Basel)] 2021 Jun 18; Vol. 10 (6). Date of Electronic Publication: 2021 Jun 18.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101637404 Publication Model: Electronic Cited Medium: Print ISSN: 2079-6382 (Print) Linking ISSN: 20796382 NLM ISO Abbreviation: Antibiotics (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, 2012-
مستخلص: The infection of Enterococcus faecalis and its interacting microorganisms in the root canal could cause persistent apical periodontitis (AP). Antibacterial root canal sealer has favorable prospects to inhibit biofilms. The purpose of this study was to investigated the antibacterial effect of root canal sealer containing dimethylaminododecyl methacrylate (DMADDM) on persistent AP in beagle dogs for the first time. Persistent AP was established by a two-step infection with Enterococcus faecalis and multi-bacteria ( Enterococcus faecalis , Lactobacillus acidophilus , Actinomyces naeslundii , Streptococcus gordonii ). Root canal sealer containing DMADDM (0%, 1.25%, 2.5%) was used to complete root canal filling. The volume of lesions and inflammatory grade in the apical area were evaluated by cone beam computer tomography (CBCT) and hematoxylin-eosin staining. Both Enterococcus-faecalis- and multi-bacteria-induced persistent AP caused severe apical destruction, and there were no significant differences in pathogenicity between them. DMADDM-modified sealer significantly reduced the volume of periapical lesion and inflammatory grade compared with the control group, among them, the therapeutic effect of the 2.5% group was better than the 1.25% group. In addition, E. faecalis -induced reinfection was more sensitive to the 2.5% group than multi-bacteria reinfection. This study shows that root canal sealer containing DMADDM had a remarkable therapeutic effect on persistent AP, especially on E. faecalis -induced reinfection.
References: Eur J Oral Sci. 2002 Jun;110(3):246-53. (PMID: 12120711)
J Dent Res. 2012 Jun;91(6):598-604. (PMID: 22492276)
Sci Rep. 2019 Jul 23;9(1):10632. (PMID: 31337813)
J Endod. 2015 Aug;41(8):1353-8. (PMID: 25958178)
Aust Dent J. 2007 Mar;52(1 Suppl):S64-82. (PMID: 17546863)
J Endod. 2012 Mar;38(3):318-23. (PMID: 22341068)
Int J Oral Sci. 2016 Jun 30;8(2):76-83. (PMID: 27357319)
J Endod. 2014 Nov;40(11):1778-83. (PMID: 25227214)
J Endod. 2016 Aug;42(8):1233-8. (PMID: 27316318)
J Dent Res. 2014 Dec;93(12):1277-82. (PMID: 25192898)
J Dent. 2013 Apr;41(4):345-55. (PMID: 23353068)
Dent Mater. 2012 May;28(5):561-72. (PMID: 22305716)
Int Endod J. 2006 Apr;39(4):249-81. (PMID: 16584489)
J Endod. 2009 Jan;35(1):46-9. (PMID: 19084123)
J Endod. 2015 Aug;41(8):1288-93. (PMID: 26055433)
Arch Oral Biol. 2009 Aug;54(8):764-71. (PMID: 19497558)
Dent Mater. 2018 Mar;34(3):400-411. (PMID: 29269159)
J Dent Res. 2020 Nov;99(12):1368-1376. (PMID: 32600095)
Oral Microbiol Immunol. 2001 Dec;16(6):332-7. (PMID: 11737655)
Biochim Biophys Acta Mol Basis Dis. 2018 Jan;1864(1):226-237. (PMID: 29066283)
Int Endod J. 2003 Jan;36(1):1-11. (PMID: 12656508)
Br Dent J. 2014 Mar;216(6):305-12. (PMID: 24651336)
Int Endod J. 2019 Feb;52(2):201-210. (PMID: 30099741)
J Endod. 2017 Jan;43(1):63-68. (PMID: 27847139)
J Microbiol. 2009 Feb;47(1):101-9. (PMID: 19229497)
J Endod. 2014 Jul;40(7):899-906. (PMID: 24935532)
Mater Sci Eng C Mater Biol Appl. 2020 Jun;111:110856. (PMID: 32279748)
Int Endod J. 2015 Oct;48(10):916-25. (PMID: 26172346)
Front Microbiol. 2018 Oct 09;9:2374. (PMID: 30356779)
J Dent Res. 2017 Jul;96(8):855-863. (PMID: 28530844)
J Endod. 2011 Mar;37(3):390-7. (PMID: 21329828)
J Endod. 2008 Jul;34(7):822-5. (PMID: 18570987)
J Endod. 2010 Mar;36(3):383-99. (PMID: 20171352)
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Jan;97(1):85-94. (PMID: 14716262)
Materials (Basel). 2015 Jun;8(6):3532-3549. (PMID: 26635932)
Int J Mol Sci. 2014 Jul 18;15(7):12791-806. (PMID: 25046750)
J Endod. 2012 May;38(5):628-35. (PMID: 22515891)
Cell Microbiol. 2003 Oct;5(10):661-9. (PMID: 12969372)
J Dent Res. 2015 Apr;94(4):622-9. (PMID: 25715378)
J Endod. 2006 Feb;32(2):93-8. (PMID: 16427453)
Int Endod J. 2011 Aug;44(8):697-730. (PMID: 21535021)
معلومات مُعتمدة: 81870759 National Natural Science Foundation of China; 82071106 National Natural Science Foundation of China; 81870778 National Natural Science Foundation of China; 81991500 National Natural Science Foundation of China; 81991501 National Natural Science Foundation of China; 2017HH0008 International Science and Technology Program of Sichuan
فهرسة مساهمة: Keywords: Enterococcus faecalis; beagle dogs; dimethylaminododecyl methacrylate; persistent apical periodontitis; root canal sealer
تواريخ الأحداث: Date Created: 20210702 Latest Revision: 20210710
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC8233789
DOI: 10.3390/antibiotics10060741
PMID: 34207470
قاعدة البيانات: MEDLINE
الوصف
تدمد:2079-6382
DOI:10.3390/antibiotics10060741