دورية أكاديمية
Peripheral Nervous System Involvement in Non-Primary Pediatric Cancer: From Neurotoxicity to Possible Etiologies.
| العنوان: | Peripheral Nervous System Involvement in Non-Primary Pediatric Cancer: From Neurotoxicity to Possible Etiologies. |
|---|---|
| المؤلفون: | Pro S; Child Neurology Unit, Department of Neuroscience, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy., Vinti L; Department of Hematology/Oncology, Gene Therapy and Hematopoietic Transplantation, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy., Boni A; Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy., Mastronuzzi A; Department of Hematology/Oncology, Gene Therapy and Hematopoietic Transplantation, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy., Scilipoti M; Department of Emergency, Acceptance and General Pediatrics, Bambino Gesù Children Hospital, IRCCS, 00165 Rome, Italy., Velardi M; Child Neurology, NESMOS Department, Faculty of Medicine and Psychology, Sant'Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy., Caroleo AM; Department of Hematology/Oncology, Gene Therapy and Hematopoietic Transplantation, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy., Farina E; Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy., Badolato F; Child Neurology, NESMOS Department, Faculty of Medicine and Psychology, Sant'Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy., Alessi I; Department of Hematology/Oncology, Gene Therapy and Hematopoietic Transplantation, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy., Di Nardo G; Child Neurology, NESMOS Department, Faculty of Medicine and Psychology, Sant'Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy., Carai A; Neurosurgery Unit, Department of Neuroscience, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy., Valeriani M; Child Neurology Unit, Department of Neuroscience, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy., Reale A; Department of Emergency, Acceptance and General Pediatrics, Bambino Gesù Children Hospital, IRCCS, 00165 Rome, Italy., Parisi P; Child Neurology, NESMOS Department, Faculty of Medicine and Psychology, Sant'Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy., Raucci U; Department of Emergency, Acceptance and General Pediatrics, Bambino Gesù Children Hospital, IRCCS, 00165 Rome, Italy. |
| المصدر: | Journal of clinical medicine [J Clin Med] 2021 Jul 06; Vol. 10 (14). Date of Electronic Publication: 2021 Jul 06. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101606588 Publication Model: Electronic Cited Medium: Print ISSN: 2077-0383 (Print) Linking ISSN: 20770383 NLM ISO Abbreviation: J Clin Med Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI AG, [2012]- |
| مستخلص: | Peripheral neuropathy is a well described complication in children with cancer. Oncologists are generally well aware of the toxicity of the main agents, but fear the side effects of new drugs. As chemotherapeutic agents have been correlated with the activation of the immune system such as in Chemotherapy Induced Peripheral Neuropathy (CIPN), an abnormal response can lead to Autoimmune Peripheral Neuropathy (APN). Although less frequent but more severe, Radiation Induced Peripheral Neuropathy may be related to irreversible peripheral nervous system (PNS). Pediatric cancer patients also have a higher risk of entering a Pediatric Intensive Care Unit for complications related to therapy and disease. Injury to peripheral nerves is cumulative, and frequently, the additional stress of a malignancy and its therapy can unmask a subclinical neuropathy. Emerging risk factors for CIPN include treatment factors such as dose, duration and concurrent medication along with patient factors, namely age and inherited susceptibilities. The recent identification of individual genetic variations has advanced the understanding of physiopathological mechanisms and may direct future treatment approaches. More research is needed on pharmacological agents for the prevention or treatment of the condition as well as rehabilitation interventions, in order to allow for the simultaneous delivery of optimal cancer therapy and the mitigation of toxicity associated with pain and functional impairment. The aim of this paper is to review literature data regarding PNS complications in non-primary pediatric cancer. |
| References: | Neuro Oncol. 2014 Apr;16(4):589-93. (PMID: 24482447) Pediatr Blood Cancer. 2010 Dec 1;55(6):1234-5. (PMID: 20544812) Front Neurosci. 2013 Mar 12;7:30. (PMID: 23486839) J Neurobiol. 1980 May;11(3):251-64. (PMID: 6156229) J Clin Oncol. 2006 Sep 20;24(27):4507-14. (PMID: 16940275) Pediatr Phys Ther. 2018 Apr;30(2):119-124. (PMID: 29498961) Curr Opin Support Palliat Care. 2013 Jun;7(2):131-8. (PMID: 23635878) Neurobiol Dis. 2011 Mar;41(3):661-8. (PMID: 21145397) JAMA Neurol. 2016 Jul 1;73(7):860-6. (PMID: 27183099) J Biomech. 2015 Oct 15;48(13):3559-67. (PMID: 26321364) Ann Neurol. 2014 Nov;76(5):727-37. (PMID: 25164601) J Child Neurol. 2014 Jul;29(7):932-7. (PMID: 23781018) Aliment Pharmacol Ther. 2008 Jul;28(1):25-42. (PMID: 18410560) J Clin Neurophysiol. 2013 Apr;30(2):199-203. (PMID: 23545771) Handb Clin Neurol. 2016;138:263-82. (PMID: 27637963) Pediatr Blood Cancer. 2011 Aug;57(2):252-7. (PMID: 21671362) JAMA. 1984 Nov 23-30;252(20):2862-3. (PMID: 6092732) Cancer. 1998 Jan 1;82(1):200-7. (PMID: 9428498) Neurogastroenterol Motil. 2016 Feb;28(2):206-16. (PMID: 26547262) J Clin Oncol. 2005 May 20;23(15):3396-403. (PMID: 15908652) J Neurosci. 2006 Jan 4;26(1):246-55. (PMID: 16399694) Expert Opin Drug Saf. 2011 May;10(3):407-17. (PMID: 21210753) Maturitas. 2017 Nov;105:100-106. (PMID: 28545905) Cancer Treat Rev. 1994 Apr;20(2):191-214. (PMID: 8156541) Cancer Treat Rev. 1998 Aug;24(4):265-81. (PMID: 9805507) J Immunother Cancer. 2019 May 22;7(1):134. (PMID: 31118078) J Exp Med. 2018 May 7;215(5):1301-1313. (PMID: 29703731) Anticancer Drugs. 2004 Nov;15(10):997-9. (PMID: 15514570) Cancer. 2002 May 1;94(9):2466-73. (PMID: 12015772) J Clin Oncol. 2007 Aug 10;25(23):3407-14. (PMID: 17606974) J Immunol. 2002 Sep 1;169(5):2719-26. (PMID: 12193746) J Neurol Sci. 2008 Dec 15;275(1-2):164-6. (PMID: 18804790) CA Cancer J Clin. 2013 Nov-Dec;63(6):419-37. (PMID: 24590861) Clin Neurophysiol. 2019 Aug;130(8):1440-1445. (PMID: 31103410) Int J Mol Sci. 2019 Nov 28;20(23):. (PMID: 31795299) Front Mol Neurosci. 2017 May 31;10:174. (PMID: 28620280) J Pediatr Neurosci. 2015 Jan-Mar;10(1):64-6. (PMID: 25878750) Semin Pediatr Neurol. 2012 Mar;19(1):9-17. (PMID: 22641071) J Pediatr Hematol Oncol. 2017 May;39(4):266-271. (PMID: 28375940) J Pediatr Hematol Oncol. 2003 Apr;25(4):316-20. (PMID: 12679647) Gastroenterol Res Pract. 2020 Sep 8;2020:8024171. (PMID: 32963521) J Neurol Neurosurg Psychiatry. 2005 Jun;76 Suppl 2:ii23-31. (PMID: 15961865) Support Care Cancer. 2014 Feb;22(2):359-66. (PMID: 24072474) Lancet Child Adolesc Health. 2018 Oct;2(10):744-754. (PMID: 30236383) Crit Rev Oncol Hematol. 2017 Jun;114:114-130. (PMID: 28477739) Gastroenterology. 2000 Nov;119(5):1276-85. (PMID: 11054385) Front Neurosci. 2017 Aug 31;11:481. (PMID: 28912674) Indian J Pediatr. 2006 Jun;73(6):531-3. (PMID: 16816519) Br J Haematol. 2017 Oct;179(2):294-297. (PMID: 28961308) Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6704-9. (PMID: 22493249) Muscle Nerve. 2008 Mar;37(3):281-92. (PMID: 18041052) J Pediatr Hematol Oncol. 2003 Jul;25(7):539-42. (PMID: 12847320) Folia Neuropathol. 2007;45(1):26-30. (PMID: 17357008) Muscle Nerve. 2005 Aug;32(2):140-63. (PMID: 15825186) Asia Pac J Clin Oncol. 2012 Jun;8(2):201-4. (PMID: 22524580) Eur J Cancer. 2004 Nov;40(16):2445-51. (PMID: 15519518) Neurol Res. 2016 Feb;38(2):124-9. (PMID: 27118608) Leuk Res. 2015 Jul;39(7):786-92. (PMID: 25891070) Mycoses. 2012 Jul;55(4):290-7. (PMID: 22126626) Br J Pharmacol. 2018 Feb;175(4):656-677. (PMID: 29194564) Br J Pharmacol. 2016 Dec;173(24):3502-3521. (PMID: 27714760) J Peripher Nerv Syst. 2014 Jun;19(2):127-35. (PMID: 24814100) J Investig Med High Impact Case Rep. 2018 Feb 26;6:2324709618758349. (PMID: 29511693) Acta Neuropathol. 2010 Feb;119(2):235-48. (PMID: 19727778) Arch Dis Child. 2002 Feb;86(2):103-7. (PMID: 11827903) Curr Opin Support Palliat Care. 2020 Sep;14(3):293-300. (PMID: 32769620) Toxicology. 2012 Jan 27;291(1-3):1-9. (PMID: 22079234) Pediatr Blood Cancer. 2018 Jul;65(7):e27064. (PMID: 29630779) Brain Nerve. 2011 Jun;63(6):549-55. (PMID: 21613658) J Neurol. 2012 Sep;259(9):1936-43. (PMID: 22349867) J Child Neurol. 2012 Jul;27(7):867-74. (PMID: 22241706) J Neuroophthalmol. 2019 Sep;39(3):394-396. (PMID: 30801443) J Neuroimmunol. 1999 Dec;100(1-2):74-97. (PMID: 10695718) J Clin Oncol. 2005 May 20;23(15):3376-82. (PMID: 15908649) JAMA Neurol. 2018 Aug 1;75(8):980-988. (PMID: 29799906) Ann Oncol. 2000 Feb;11(2):217-20. (PMID: 10761759) Eur J Cancer. 2016 Jun;60:210-25. (PMID: 27084345) Nat Rev Gastroenterol Hepatol. 2020 Jun;17(6):338-351. (PMID: 32152479) J Cell Biol. 2012 Jan 9;196(1):7-18. (PMID: 22232700) Exp Neurol. 2007 Mar;204(1):317-25. (PMID: 17214983) J Clin Oncol. 2011 Feb 10;29(5):551-65. (PMID: 21220611) Neurology. 1981 Jan;31(1):45-50. (PMID: 6256684) Neurogastroenterol Motil. 2018 Nov;30(11):e13399. (PMID: 29971865) Clin Pharmacol Ther. 2011 Sep;90(3):377-87. (PMID: 21814197) Pediatr Blood Cancer. 2017 Jan;64(1):180-187. (PMID: 27567009) Nat Genet. 2001 Apr;27(4):383-91. (PMID: 11279519) Ann Oncol. 2013 Feb;24(2):454-462. (PMID: 22910842) J Peripher Nerv Syst. 2015 Mar;20(1):37-46. (PMID: 25977177) Front Physiol. 2017 Jun 08;8:391. (PMID: 28642718) Radiother Oncol. 2012 Dec;105(3):273-82. (PMID: 23245644) J Clin Oncol. 2007 Aug 10;25(23):3415-20. (PMID: 17606972) Chemother Res Pract. 2012;2012:913848. (PMID: 22482054) Ther Adv Neurol Disord. 2018 Sep 14;11:1756286418799864. (PMID: 30245744) Nat Rev Clin Oncol. 2016 Feb;13(2):92-105. (PMID: 26391778) J Peripher Nerv Syst. 2019 Oct;24 Suppl 2:S6-S12. (PMID: 31647155) J Clin Oncol. 2020 Oct 1;38(28):3282-3293. (PMID: 32813610) Brain. 2016 Dec;139(Pt 12):3092-3108. (PMID: 27797810) Arch Phys Med Rehabil. 2013 Aug;94(8):1451-7. (PMID: 23537607) Int J Mol Sci. 2019 Jun 14;20(12):. (PMID: 31197114) J Immunother. 2015 Feb-Mar;38(2):77-9. (PMID: 25658617) J Clin Oncol. 2020 Oct 1;38(28):3325-3348. (PMID: 32663120) Cancer Treat Rev. 2016 Nov;50:118-128. (PMID: 27664395) Radiother Oncol. 2012 Dec;105(3):305-12. (PMID: 23021793) Neurotoxicology. 2013 Jul;37:231-9. (PMID: 23711742) Eur J Cancer. 2016 Dec;69:28-38. (PMID: 27814471) Pediatr Blood Cancer. 2013 Jul;60(7):1083-94. (PMID: 23418018) Indian J Pediatr. 2010 Jun;77(6):681-3. (PMID: 20532679) Paediatr Drugs. 2019 Apr;21(2):59-70. (PMID: 30761460) Neurology. 1969 Apr;19(4):367-74. (PMID: 5813374) J Neurol. 1990 Jul;237(4):247-50. (PMID: 2391547) Cureus. 2013 Jun 14;5(6):. (PMID: 25144779) Cell Mol Life Sci. 2014 May;71(10):1961-75. (PMID: 24061536) Eur J Paediatr Neurol. 2009 Jul;13(4):332-6. (PMID: 18774740) N Engl J Med. 2004 Jun 3;350(23):2343-51. (PMID: 15175436) Pediatr Blood Cancer. 2004 Feb;42(2):139-44. (PMID: 14752877) Ann Pharmacother. 2000 Oct;34(10):1136-8. (PMID: 11054980) Am J Cancer Res. 2016 Nov 01;6(11):2416-2430. (PMID: 27904761) J Pediatr. 1983 Feb;102(2):314-7. (PMID: 6681630) Curr Opin Crit Care. 2002 Aug;8(4):302-10. (PMID: 12386490) Muscle Nerve. 2015 Dec;52(6):981-5. (PMID: 25758843) J Clin Oncol. 2014 Jun 20;32(18):1941-67. (PMID: 24733808) PM R. 2017 Sep;9(9S2):S385-S397. (PMID: 28942910) Neurosci Bull. 2018 Feb;34(1):64-73. (PMID: 28612319) Neurol Clin. 2010 Feb;28(1):217-34. (PMID: 19932383) Neurogastroenterol Motil. 2011 Apr;23(4):370-8, e162-3. (PMID: 21299719) Science. 2012 Jun 8;336(6086):1268-73. (PMID: 22674334) Pediatr Blood Cancer. 2011 Mar;56(3):361-7. (PMID: 21225912) Can J Neurol Sci. 2014 Jul;41(4):442-7. (PMID: 24878467) Nat Genet. 2001 Mar;27(3):309-12. (PMID: 11242114) Eur J Cancer. 2017 Mar;73:22-29. (PMID: 28104535) Pediatr Hematol Oncol. 2012 Feb;29(1):62-7. (PMID: 22304011) Free Radic Biol Med. 2011 Sep 1;51(5):951-66. (PMID: 21277369) N Engl J Med. 2018 Aug 2;379(5):485-487. (PMID: 30067934) Neurology. 1985 Jan;35(1):1-7. (PMID: 2981416) Clin J Pain. 2019 Jun;35(6):509-514. (PMID: 30985402) J Neurochem. 2004 Feb;88(4):939-47. (PMID: 14756815) Nat Rev Clin Oncol. 2009 Oct;6(10):596-603. (PMID: 19707193) Clin Neurophysiol. 2017 Jul;128(7):1166-1175. (PMID: 28511129) BMJ Case Rep. 2017 Apr 24;2017:. (PMID: 28438772) Exp Neurol. 2012 Dec;238(2):225-34. (PMID: 22947198) Int J Mol Sci. 2021 Apr 16;22(8):. (PMID: 33923421) Neurogastroenterol Motil. 2016 Dec;28(12):1861-1875. (PMID: 27353132) Clin Colorectal Cancer. 2016 Sep;15(3):e133-40. (PMID: 27038553) Neurotoxicology. 2013 Dec;39:124-31. (PMID: 24035926) J Oncol Pharm Pract. 2015 Aug;21(4):296-300. (PMID: 24664478) Front Pharmacol. 2017 Feb 24;8:86. (PMID: 28286483) J Neurol Neurosurg Psychiatry. 1984 Nov;47(11):1223-31. (PMID: 6094735) Cancers (Basel). 2020 May 17;12(5):. (PMID: 32429551) Muscle Nerve. 2005 May;31(5):642-5. (PMID: 15635681) Clin Neurophysiol. 2011 Mar;122(3):440-455. (PMID: 20673740) Lancet Oncol. 2017 Jan;18(1):63-74. (PMID: 27914822) Pediatr Blood Cancer. 2017 Aug;64(8):. (PMID: 28139029) Lancet Child Adolesc Health. 2020 Feb;4(2):141-150. (PMID: 31866182) J Plast Surg Hand Surg. 2014 Aug;48(4):276-80. (PMID: 24479792) Int J Mol Sci. 2019 Mar 22;20(6):. (PMID: 30909387) Muscle Nerve. 2018 Jan 17;:. (PMID: 29342325) Int J Radiat Oncol Biol Phys. 2010 Dec 1;78(5):1445-50. (PMID: 20231075) Blood. 2012 Jul 12;120(2):285-90. (PMID: 22653976) Biomed Rep. 2017 Mar;6(3):267-271. (PMID: 28451384) Cell Cycle. 2014;13(4):612-21. (PMID: 24335344) Neurotox Res. 2010 Feb;17(2):167-78. (PMID: 19609631) Pediatr Blood Cancer. 2011 Dec 15;57(7):1147-53. (PMID: 21319291) Neuroepidemiology. 2019;52(3-4):161-172. (PMID: 30669140) J Peripher Nerv Syst. 2009 Sep;14(3):184-9. (PMID: 19909482) Brain. 1996 Oct;119 ( Pt 5):1429-39. (PMID: 8931568) Clin Neurophysiol. 2008 Nov;119(11):2507-12. (PMID: 18829381) Cancer Nurs. 2013 Sep-Oct;36(5):E49-60. (PMID: 23842524) Pediatr Blood Cancer. 2010 Jan;54(1):161-5. (PMID: 19760771) Biochemistry. 1996 May 28;35(21):6806-14. (PMID: 8639632) Pediatr Int. 2017 Mar;59(3):293-302. (PMID: 27543960) J Immunother. 2013 Jan;36(1):77-8. (PMID: 23211620) Oncologist. 2020 Jan;25(1):e194-e197. (PMID: 31615948) N Engl J Med. 1990 Jan 11;322(2):126-7. (PMID: 2152970) J Cancer Res Ther. 2013 Apr-Jun;9(2):335-6. (PMID: 23771393) Hematol Oncol Clin North Am. 2009 Oct;23(5):1121-35, vii-viii. (PMID: 19825456) J Autoimmun. 2001 May;16(3):219-27. (PMID: 11334486) Neurology. 1985 Aug;35(8):1261. (PMID: 4022372) Trends Pharmacol Sci. 2013 Feb;34(2):110-8. (PMID: 23318139) Med Pediatr Oncol. 1995 Aug;25(2):113-6. (PMID: 7603395) Support Care Cancer. 2013 Mar;21(3):847-56. (PMID: 22993026) Eur J Cancer. 2010 Feb;46(3):479-94. (PMID: 20045310) Cancer. 2012 Feb 1;118(3):828-38. (PMID: 21766297) J Pediatr Hematol Oncol. 2012 Apr;34(3):e110-3. (PMID: 22246161) J Histochem Cytochem. 2016 Sep;64(9):530-45. (PMID: 27389702) J Clin Oncol. 2013 Jul 1;31(19):e327-31. (PMID: 23715575) Int J Radiat Oncol Biol Phys. 1993 Apr 30;26(1):43-9. (PMID: 8387067) Neuro Oncol. 2008 Dec;10(6):1035-9. (PMID: 18755918) Pediatr Crit Care Med. 2007 Jan;8(1):18-22. (PMID: 17251877) Nat Rev Cancer. 2004 Apr;4(4):253-65. (PMID: 15057285) Am J Hematol. 2010 Aug;85(8):608. (PMID: 20658590) Stereotact Funct Neurosurg. 2008;86(6):359-66. (PMID: 18854663) Continuum (Minneap Minn). 2012 Feb;18(1):85-105. (PMID: 22810071) Lancet Oncol. 2014 Dec;15(13):1503-1512. (PMID: 25456369) Cochrane Database Syst Rev. 2005 Jul 20;(3):CD005005. (PMID: 16034961) J Clin Oncol. 2016 Oct 10;34(29):3537-3543. (PMID: 27573663) Neurosci Lett. 2015 Jun 2;596:90-107. (PMID: 25459280) Pediatr Hematol Oncol. 2001 Jul-Aug;18(5):343-6. (PMID: 11452406) Clin Pharmacokinet. 1991 Oct;21(4):242-61. (PMID: 1760899) Cochrane Database Syst Rev. 2007 Jan 24;(1):CD005228. (PMID: 17253547) Pediatr Blood Cancer. 2012 Mar;58(3):334-43. (PMID: 22038641) Toxics. 2015 Jun 05;3(2):198-223. (PMID: 29056658) Clin Oncol (R Coll Radiol). 1998;10(6):399-400. (PMID: 9890543) |
| فهرسة مساهمة: | Keywords: complications; pediatric cancer; peripheral nervous system; peripheral neuropathy |
| تواريخ الأحداث: | Date Created: 20210724 Latest Revision: 20240813 |
| رمز التحديث: | 20240813 |
| مُعرف محوري في PubMed: | PMC8303855 |
| DOI: | 10.3390/jcm10143016 |
| PMID: | 34300182 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder كن أول من يترك تعليقا!