دورية أكاديمية
أعرض في EDS

Quantitative investigation of the effect of surgically induced hypoparathyroidism on cataract development.

التفاصيل البيبلوغرافية
العنوان: Quantitative investigation of the effect of surgically induced hypoparathyroidism on cataract development.
المؤلفون: Koçer AM; Department of Ophthalmology, Dortyol Public Hospital, Dörtyol, Hatay, Turkey. alimertkocer@gmail.com., Şekeroğlu MA; Department of Ophthalmology, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey., Önder ÇE; Department of Endocrinology, Ankara Training and Research Hospital, Ankara, Turkey., Çevik S; Department of Ophthalmology, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey., Söğüt FE; Department of Ophthalmology, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey., Kuşkonmaz ŞM; Department of Endocrinology, Ankara Training and Research Hospital, Ankara, Turkey., Doğuizi S; Department of Ophthalmology, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.
المصدر: Journal of bone and mineral metabolism [J Bone Miner Metab] 2022 Jan; Vol. 40 (1), pp. 92-100. Date of Electronic Publication: 2021 Jul 27.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Japanese Society of Bone and Mineral Metabolism Country of Publication: Japan NLM ID: 9436705 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-5604 (Electronic) Linking ISSN: 09148779 NLM ISO Abbreviation: J Bone Miner Metab Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Tokyo : Japanese Society of Bone and Mineral Metabolism, [1988-
مواضيع طبية MeSH: Cataract*/etiology , Hypoparathyroidism*/etiology , Lens, Crystalline*, Densitometry ; Female ; Humans
مستخلص: Introduction: Although cataract formation is known in hypoparathyroidism, lens clarity and its correlation with clinical parameters have not been investigated quantitatively before in patients with hypoparathyroidism. The aim of this study was to compare the crystalline lens clarity of patients with surgically induced hypoparathyroidism and healthy subjects.
Materials and Methods: Forty female patients with surgically induced hypoparathyroidism and 38 age-matched healthy female subjects were enrolled in this study. Scheimpflug corneal topography was performed to measure lens density (LD) and thickness (LT). Serum calcium, inorganic phosphorus, parathyroid hormone (PTH) levels, and disease duration were recorded.
Results: No statistically significant difference was observed between the hypoparathyroidism and control groups in the Pentacam densitometry zones 1-2-3, LT, and average and maximum LD (p > 0.05 for all). Nine blue-dot-like, two cortical, and two posterior subcapsular cataracts were detected in the hypoparathyroidism group. The frequency of total and blue-dot-like cataracts was significantly higher in the hypoparathyroidism group than in the control group (p = 0.008 and p = 0.002, respectively). In the hypoparathyroidism group, a significant correlation was observed between the maximum LD and the hypoparathyroidism duration (ß = 0.420, p = 0.017), and the maximum LD and serum PTH level (ß = -0.332, p = 0.049).
Conclusion: The clarity of the crystalline lens may decrease in surgically induced hypoparathyroidism patients depending on the disease duration and PTH levels. Additionally, this study detected an increased frequency of blue-dot-like cataract in the patient group, which may be due to the effect of hypoparathyroidism.
(© 2021. The Japanese Society Bone and Mineral Research.)
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فهرسة مساهمة: Keywords: Blue-dot cataract; Hypoparathyroidism; Lens densitometry
تواريخ الأحداث: Date Created: 20210727 Date Completed: 20220118 Latest Revision: 20220118
رمز التحديث: 20240829
DOI: 10.1007/s00774-021-01257-8
PMID: 34313840
قاعدة البيانات: MEDLINE
الوصف
تدمد:1435-5604
DOI:10.1007/s00774-021-01257-8