دورية أكاديمية
أعرض في EDS

Psychosocial interventions and needs among individuals and families with Li-Fraumeni syndrome: A scoping review.

التفاصيل البيبلوغرافية
العنوان: Psychosocial interventions and needs among individuals and families with Li-Fraumeni syndrome: A scoping review.
المؤلفون: Barnett M; Department of Psychiatry, Memorial Sloan Kettering Cancer Center, New York City, USA., Breen KE; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, USA., Kennedy JA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, USA., Hernandez M; Medical Library, Memorial Sloan Kettering Cancer Center, New York City, USA.; Medical Library, City University of New York School of Medicine, New York City, USA., Matsoukas K; Medical Library, Memorial Sloan Kettering Cancer Center, New York City, USA., MacGregor M; Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
المصدر: Clinical genetics [Clin Genet] 2022 Feb; Vol. 101 (2), pp. 161-182. Date of Electronic Publication: 2021 Aug 23.
نوع المنشور: Journal Article; Meta-Analysis; Review
اللغة: English
بيانات الدورية: Publisher: Munksgaard Country of Publication: Denmark NLM ID: 0253664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1399-0004 (Electronic) Linking ISSN: 00099163 NLM ISO Abbreviation: Clin Genet Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Copenhagen, Munksgaard.
مواضيع طبية MeSH: Health Services Needs and Demand* , Psychosocial Intervention*/methods, Caregivers/*psychology , Li-Fraumeni Syndrome/*psychology, Age Factors ; Disease Management ; Genes, p53 ; Genetic Predisposition to Disease ; Genetic Testing ; Humans ; Li-Fraumeni Syndrome/diagnosis ; Li-Fraumeni Syndrome/etiology ; Li-Fraumeni Syndrome/therapy ; Public Health Surveillance ; Social Support
مستخلص: Li-Fraumeni syndrome (LFS), a rare cancer predisposition syndrome caused by germline mutations in the TP53 gene, is associated with significant lifetime risk of developing cancer and warrants extensive and long-term surveillance. There are psychosocial impacts on individuals and families living with this condition, from the initial diagnosis throughout multiple stages across the lifespan, but these impacts have not been systematically reviewed and organized. The objective of this scoping review was to synthesize and characterize the literature on psychosocial screening and outcomes, educational needs, support services, and available interventions for patients and families with LFS. A systematic search of six databases was most recently conducted in August 2020: (PubMed/MEDLINE (NLM), EMBASE (Elsevier), Cochrane Library (Wiley), CINAHL (EBSCO), PsycINFO (OVID), and Web of Science (Clarivate Analytics). A total of 15 757 titles were screened, and 24 articles included. Several important themes were identified across studies: factors associated with TP53 genetic testing, LFS surveillance, psychological outcomes, and communication. Findings related to these themes were organized into age-specific categories (age agnostic/across the lifespan, childhood, adolescence and young adulthood, and adulthood).
(© 2021 John Wiley & Sons A/S . Published by John Wiley & Sons Ltd.)
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فهرسة مساهمة: Keywords: Li-Fraumeni syndrome; TP53 germline mutation; cancer screening; genetic counseling; psycho-oncology; scoping review; systematic review
تواريخ الأحداث: Date Created: 20210806 Date Completed: 20220328 Latest Revision: 20220328
رمز التحديث: 20231215
DOI: 10.1111/cge.14042
PMID: 34355387
قاعدة البيانات: MEDLINE
الوصف
تدمد:1399-0004
DOI:10.1111/cge.14042