دورية أكاديمية
أعرض في EDS

Predicting factors for pulmonary embolism response team activation in a general pulmonary embolism population.

التفاصيل البيبلوغرافية
العنوان: Predicting factors for pulmonary embolism response team activation in a general pulmonary embolism population.
المؤلفون: Mortensen CS; Center for Vascular Emergencies, Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. csm@clin.au.dk.; Department of Cardiology, Aarhus University Hospital, Århus, Denmark. csm@clin.au.dk., Kramer A; Center for Vascular Emergencies, Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Department of Cardiology, Aarhus University Hospital, Århus, Denmark., Schultz JG; Center for Vascular Emergencies, Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Department of Cardiology, Aarhus University Hospital, Århus, Denmark., Giordano N; Center for Vascular Emergencies, Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Zheng H; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Andersen A; Department of Cardiology, Aarhus University Hospital, Århus, Denmark., Nielsen-Kudsk JE; Department of Cardiology, Aarhus University Hospital, Århus, Denmark., Kabrhel C; Center for Vascular Emergencies, Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
المصدر: Journal of thrombosis and thrombolysis [J Thromb Thrombolysis] 2022 Feb; Vol. 53 (2), pp. 506-513. Date of Electronic Publication: 2021 Aug 09.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 9502018 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-742X (Electronic) Linking ISSN: 09295305 NLM ISO Abbreviation: J Thromb Thrombolysis Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Dordrecht ; Norwell, MA] : Kluwer Academic Publishers, c1994-
مواضيع طبية MeSH: Patient Care Team* , Pulmonary Embolism*/diagnosis , Pulmonary Embolism*/therapy, Anticoagulants ; Humans ; Massachusetts/epidemiology ; Risk Factors
مستخلص: Pulmonary embolism response teams (PERT) aim to improve treatment of acute pulmonary embolism (PE). PERT focus on intermediate- and high-risk PE patients, but recent multicenter studies show that low-risk PE patients compose one in five of all PERT cases. Conversely, not all intermediate- and high-risk PE patients elicit a PERT activation. The factors leading to PERT activations remain unknown. This study aims to describe the patient characteristics associated with PERT activation for low-risk PE patients and characteristics precluding PERT activation for intermediate/high-risk PE patients. We analysed data from all patients with confirmed PE diagnosed in the Massachusetts General Hospital Emergency Department from August 2013 to February 2017 and cross-referred these data with patients who received a PERT activation and patients who did not. Patients were stratified into low-risk or intermediate/high-risk PE. Univariate analyses were performed within each risk group comparing patients with a PERT activation and patients without. Fifteen percent (56/374) of low-risk PE patients triggered a PERT activation. Patient characteristics associated with PERT activation were: (1) vascular disease, (2) pulmonary diseases, (3) thrombophilia, (4) current use of anticoagulants, (5) central PE and (6) concurrent DVT. Thirty-five percent (110/283) of intermediate/high-risk PE patients did not elicit a PERT activation. Patient characteristics precluding a PERT activation were: (1) vascular disease, (2) malignancies and (3) asymptomatic presentation. Low-risk PE patients with PERT activations had more extensive clot burden, complex comorbidities, or had failed anticoagulation treatment. Intermediate/high-risk PE patients without PERT activations tended to have malignancies or vascular disease.
(© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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معلومات مُعتمدة: 18-L-0336 A.P. Møller Foundation
فهرسة مساهمة: Keywords: Acute care; Deep vein thrombosis; Emergency medicine; Pulmonary embolism; Rapid response team; Thromboembolism
المشرفين على المادة: 0 (Anticoagulants)
تواريخ الأحداث: Date Created: 20210809 Date Completed: 20220406 Latest Revision: 20220406
رمز التحديث: 20231215
DOI: 10.1007/s11239-021-02533-0
PMID: 34370168
قاعدة البيانات: MEDLINE
الوصف
تدمد:1573-742X
DOI:10.1007/s11239-021-02533-0