دورية أكاديمية

Candidate Genes and Proteomic Biomarkers of Serum and Urine in Medication-Overuse Headache.

التفاصيل البيبلوغرافية
العنوان: Candidate Genes and Proteomic Biomarkers of Serum and Urine in Medication-Overuse Headache.
المؤلفون: Shnayder NA; The Center of Personalized Psychiatry and Neurology, V. M. Bekhterev National Medical Research Center for Neurology and Psychiatry, 192019 Saint-Petersburg, Russia.; The Center of Collective Usage 'Molecular and Cell Technologies', V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia., Sharavii VB; The International School Medicine of the Future, I. M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia., Petrova MM; The Center of Collective Usage 'Molecular and Cell Technologies', V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia., Moskaleva PV; The Center of Collective Usage 'Molecular and Cell Technologies', V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia., Pozhilenkova EA; The Center of Collective Usage 'Molecular and Cell Technologies', V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia., Kaskaeva DS; The Center of Collective Usage 'Molecular and Cell Technologies', V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia., Tutynina OV; The Center of Collective Usage 'Molecular and Cell Technologies', V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia., Popova TE; The Yakutsk Scientific Center for Complex Medicine Problems, The Department of Epidemiology of Non-Infectious Diseases, 677018 Yakutsk, Russia., Garganeeva NP; The Department of General Medical Practice and Polyclinic Therapy, The Siberian State Medical University, 634050 Tomsk, Russia., Nasyrova RF; The Center of Personalized Psychiatry and Neurology, V. M. Bekhterev National Medical Research Center for Neurology and Psychiatry, 192019 Saint-Petersburg, Russia.
المصدر: International journal of molecular sciences [Int J Mol Sci] 2021 Aug 21; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 21.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI, [2000-
مواضيع طبية MeSH: Proteome*, Biomarkers/*blood , Biomarkers/*urine , Headache Disorders, Secondary/*blood , Headache Disorders, Secondary/*urine, Chronic Pain/blood ; Chronic Pain/drug therapy ; Chronic Pain/genetics ; Chronic Pain/urine ; Headache Disorders, Secondary/chemically induced ; Headache Disorders, Secondary/genetics ; Humans
مستخلص: Chronic headache is a topical problem of neurology, psychiatry and general practice. The medication-overuse headache (MOH) is one of the leading pathologies in the structure of chronic headache. However, early diagnosis of the MOH is challenging. We analyzed potential proteomic biomarkers of serum and urine in patients with MOH.
Methods: We searched PubMed, Springer, Scopus, Web of Science, ClinicalKey, and Google Scholar databases for English publications over the past 10 years using keywords and their combinations.
Results: We found and analyzed seven studies that met the search criteria for the purpose of the review, including 24 serum proteomic biomarkers and 25 urine proteomic biomarkers of MOH. Moreover, the candidate genes and locus of the studied serum (vitamin D-binding protein, lipocalin-type prostaglandin D2 synthase, apolipoprotein E, etc.) and urine proteomic biomarkers (uromodulin, alpha-1-microglobulin, zinc-alpha-2-glycoprotein, etc.) of MOH are presented in this review.
Conclusions: The serum and urine proteomic biomarkers of MOH can potentially help with the identification of patients with MOH development. Due to the relevance of the problem, the authors believe that further investigation of the MOH proteomic biomarkers in different ethnic and racial groups of patients with primary headache is necessary. In addition, it is important to investigate whether medications of different drug classes influence the levels of serum and urine proteomic biomarkers.
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فهرسة مساهمة: Keywords: chronic headache; headache; proteogenomics; proteomics; serum biomarker; urine biomarker
المشرفين على المادة: 0 (Biomarkers)
0 (Proteome)
تواريخ الأحداث: Date Created: 20210827 Date Completed: 20210928 Latest Revision: 20231101
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC8396559
DOI: 10.3390/ijms22169024
PMID: 34445731
قاعدة البيانات: MEDLINE