دورية أكاديمية
Energy compensation and adiposity in humans.
| العنوان: | Energy compensation and adiposity in humans. |
|---|---|
| المؤلفون: | Careau V; Department of Biology, University of Ottawa, Ottawa, ON, Canada. Electronic address: vcareau@uottawa.ca., Halsey LG; School of Life and Health Sciences, University of Roehampton, London, UK. Electronic address: l.halsey@roehampton.ac.uk., Pontzer H; Evolutionary Anthropology, Duke University, Durham, NC, USA; Duke Global Health Institute, Duke University, Durham, NC, USA. Electronic address: herman.pontzer@duke.edu., Ainslie PN; Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK., Andersen LF; Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway., Anderson LJ; University of Birmingham, Birmingham, UK., Arab L; David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Baddou I; Unité Mixte de Recherche en Nutrition et Alimentation, CNESTEN, Université Ibn Tofail URAC39, Regional Designated Center of Nutrition Associated with AFRA/IAEA, Kénitra, Morocco., Bedu-Addo K; Department of Physiology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Blaak EE; Maastricht University, Maastricht, the Netherlands., Blanc S; Nutritional Sciences, University of Georgia, Athens, GA, USA; Institut Pluridisciplinaire Hubert Curien, CNRS Université de Strasbourg, Strasbourg UMR7178, France., Bonomi AG; Phillips Research, Eindhoven, the Netherlands., Bouten CVC; Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, the Netherlands., Buchowski MS; Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, Vanderbilt University, Nashville, TN, USA., Butte NF; Department of Pediatrics, Baylor College of Medicine, USDA/ARS Children's Nutrition Research Center, Houston, TX, USA., Camps SGJA; Maastricht University, Maastricht, the Netherlands., Close GL; Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK., Cooper JA; Nutritional Sciences, University of Georgia, Athens, GA, USA., Das SK; Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA., Cooper R; Department of Public Health Sciences, Parkinson School of Health Sciences and Public Health, Loyola University, Maywood, IL, USA., Dugas LR; Department of Public Health Sciences, Parkinson School of Health Sciences and Public Health, Loyola University, Maywood, IL, USA; Division of Epidemiology and Biostatistics, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa., Eaton SD; Developmental Biology & Cancer Department, University College London, London, UK., Ekelund U; Department of Sport Medicine, Norwegian School of Sport Sciences, Oslo, Norway., Entringer S; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Institute of Medical Psychology, Berlin, Germany; University of California, Irvine, Irvine, CA, USA., Forrester T; Solutions for Developing Countries, University of the West Indies, Mona, Kingston, Jamaica., Fudge BW; University of Glasgow, Glasgow, UK., Goris AH; Maastricht University, Maastricht, the Netherlands., Gurven M; Department of Anthropology, University of California, Santa Barbara, Santa Barbara, CA, USA., Hambly C; Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, UK., El Hamdouchi A; Unité Mixte de Recherche en Nutrition et Alimentation, CNESTEN, Université Ibn Tofail URAC39, Regional Designated Center of Nutrition Associated with AFRA/IAEA, Kénitra, Morocco., Hoos MB; Maastricht University, Maastricht, the Netherlands., Hu S; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China., Joonas N; Central Health Laboratory, Ministry of Health and Wellness, Port Louis, Mauritius., Joosen AM; Maastricht University, Maastricht, the Netherlands., Katzmarzyk P; Pennington Biomedical Research Center, Baton Rouge, LA, USA., Kempen KP; Maastricht University, Maastricht, the Netherlands., Kimura M; National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan., Kraus WE; Department of Medicine, Duke University, Durham, NC, USA., Kushner RF; Northwestern University, Chicago, IL, USA., Lambert EV; Health through Physical Activity, Lifestyle and Sport Research Centre (HPALS), FIMS International Collaborating Centre of Sports Medicine, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Leonard WR; Department of Anthropology, Northwestern University, Evanston, IL, USA., Lessan N; Imperial College London Diabetes Centre, Abu Dhabi, UAE, Imperial College London, London, UK., Martin CK; Pennington Biomedical Research Center, Baton Rouge, LA, USA., Medin AC; Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway; Department of Nutrition and Public Health, Faculty of Health and Sport Sciences, University of Agder, 4630 Kristiansand, Norway., Meijer EP; Maastricht University, Maastricht, the Netherlands., Morehen JC; Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK; The FA Group, Burton-Upon-Trent, Staffordshire, UK., Morton JP; Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK., Neuhouser ML; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center and School of Public Health, University of Washington, Seattle, WA, USA., Nicklas TA; Department of Pediatrics, Baylor College of Medicine, USDA/ARS Children's Nutrition Research Center, Houston, TX, USA., Ojiambo RM; Moi University, Eldoret, Kenya; University of Global Health Equity, Kigali, Rwanda., Pietiläinen KH; Obesity Research Unit, Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki and Obesity Center, Abdominal Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Pitsiladis YP; University of Brighton, Eastbourne, UK., Plange-Rhule J; Department of Physiology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Plasqui G; Department of Nutrition and Movement Sciences, Maastricht University, Maastricht, the Netherlands., Prentice RL; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center and School of Public Health, University of Washington, Seattle, WA, USA., Rabinovich RA; University of Edinburgh, Edinburgh, UK., Racette SB; Program in Physical Therapy and Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Raichlen DA; Biological Sciences and Anthropology, University of Southern California, Los Angeles, CA, USA., Ravussin E; Central Health Laboratory, Ministry of Health and Wellness, Port Louis, Mauritius., Reilly JJ; University of Strathclyde, Glasgow, Scotland, UK., Reynolds RM; Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Roberts SB; Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA., Schuit AJ; University of Tilburg, Tilburg, the Netherlands., Sjödin AM; Department of Nutrition, Exercise and Sports, Copenhagen University, Copenhagen, Denmark., Stice E; Stanford University, Stanford, CA, USA., Urlacher SS; Department of Anthropology, Baylor University, Waco, TX, USA., Valenti G; Maastricht University, Maastricht, the Netherlands., Van Etten LM; Maastricht University, Maastricht, the Netherlands., Van Mil EA; Maastricht University, Maastricht and Lifestyle Medicine Center for Children, Jeroen Bosch Hospital's-Hertogenbosch, Maastricht, the Netherlands., Wells JCK; Population, Policy and Practice Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, UK., Wilson G; Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK., Wood BM; University of California, Los Angeles, Los Angeles, USA; Max Planck Institute for Evolutionary Anthropology, Department of Human Behavior, Ecology, and Culture, Leipzig, Germany., Yanovski J; Growth and Obesity, Division of Intramural Research, NIH, Bethesda, MD, USA., Yoshida T; Institute for Active Health, Kyoto University of Advanced Science, Kyoto, Japan., Zhang X; Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, UK; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China., Murphy-Alford AJ; Nutritional and Health Related Environmental Studies Section, Division of Human Health, International Atomic Energy Agency, Vienna, Austria., Loechl CU; Nutritional and Health Related Environmental Studies Section, Division of Human Health, International Atomic Energy Agency, Vienna, Austria., Luke AH; Department of Public Health Sciences, Loyola University Chicago, Maywood, IL, USA. Electronic address: aluke@luc.edu., Rood J; Pennington Biomedical Research Center, Baton Rouge, LA, USA. Electronic address: jennifer.rood@pbrc.edu., Sagayama H; Faculty of Health and Sport Sciences, University of Tsukuba, Ibaraki, Japan. Electronic address: sagayama.hiroyuki.ka@u.tsukuba.ac.jp., Schoeller DA; Biotech Center and Nutritional Sciences, University of Wisconsin, Madison, WI, USA. Electronic address: dschoell@nutrisci.wisc.edu., Wong WW; Department of Pediatrics, Baylor College of Medicine, USDA/ARS Children's Nutrition Research Center, Houston, TX, USA. Electronic address: wwong@bcm.edu., Yamada Y; National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan; Institute for Active Health, Kyoto University of Advanced Science, Kyoto, Japan. Electronic address: yyamada831@gmail.com., Speakman JR; Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China; Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, UK; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China; Shenzhen Key Laboratory of Metabolic Health, CAS Center of Excellence in Animal Evolution and Genetics, Kunming, China. Electronic address: j.speakman@abdn.ac.uk. |
| مؤلفون مشاركون: | IAEA DLW database group |
| المصدر: | Current biology : CB [Curr Biol] 2021 Oct 25; Vol. 31 (20), pp. 4659-4666.e2. Date of Electronic Publication: 2021 Aug 27. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cell Press Country of Publication: England NLM ID: 9107782 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0445 (Electronic) Linking ISSN: 09609822 NLM ISO Abbreviation: Curr Biol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Cambridge, MA : Cell Press Original Publication: London, UK : Current Biology Ltd., c1991- |
| مواضيع طبية MeSH: | Adiposity* , Obesity*/metabolism, Energy Intake ; Energy Metabolism/physiology ; Humans |
| مستخلص: | Understanding the impacts of activity on energy balance is crucial. Increasing levels of activity may bring diminishing returns in energy expenditure because of compensatory responses in non-activity energy expenditures. 1-3 This suggestion has profound implications for both the evolution of metabolism and human health. It implies that a long-term increase in activity does not directly translate into an increase in total energy expenditure (TEE) because other components of TEE may decrease in response-energy compensation. We used the largest dataset compiled on adult TEE and basal energy expenditure (BEE) (n = 1,754) of people living normal lives to find that energy compensation by a typical human averages 28% due to reduced BEE; this suggests that only 72% of the extra calories we burn from additional activity translates into extra calories burned that day. Moreover, the degree of energy compensation varied considerably between people of different body compositions. This association between compensation and adiposity could be due to among-individual differences in compensation: people who compensate more may be more likely to accumulate body fat. Alternatively, the process might occur within individuals: as we get fatter, our body might compensate more strongly for the calories burned during activity, making losing fat progressively more difficult. Determining the causality of the relationship between energy compensation and adiposity will be key to improving public health strategies regarding obesity. Competing Interests: Declaration of interests The authors have no conflicts of interest to declare. (Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.) |
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| معلومات مُعتمدة: | R01 HL082988 United States HL NHLBI NIH HHS; U01 HL138638 United States HL NHLBI NIH HHS; R01 DK080763 United States DK NIDDK NIH HHS; U01 AG020480 United States AG NIA NIH HHS; U01 AG022132 United States AG NIA NIH HHS; S10 RR026764 United States RR NCRR NIH HHS; P30 DK072476 United States DK NIDDK NIH HHS; P30 DK056341 United States DK NIDDK NIH HHS; N01WH74315 United States WH WHI NIH HHS; R01 AG024119 United States AG NIA NIH HHS; R01 DK080760 United States DK NIDDK NIH HHS; R01 DK069465 United States DK NIDDK NIH HHS; R56 AG067200 United States AG NIA NIH HHS; R01 DP000092 United States DP NCCDPHP CDC HHS; R01 DK074387 United States DK NIDDK NIH HHS; R33 AG070455 United States AG NIA NIH HHS; L30 AA015010 United States AA NIAAA NIH HHS; U01 AR071160 United States AR NIAMS NIH HHS; T32 HL007633 United States HL NHLBI NIH HHS; R01 DK085163 United States DK NIDDK NIH HHS; K23 DK068052 United States DK NIDDK NIH HHS; U01 AG020478 United States AG NIA NIH HHS; R01 CA107545 United States CA NCI NIH HHS; Z99 HD999999 United States ImNIH Intramural NIH HHS; R21 DK098765 United States DK NIDDK NIH HHS; R01 AG029914 United States AG NIA NIH HHS; R01 HD065825 United States HD NICHD NIH HHS; R01 CA119171 United States CA NCI NIH HHS; UL1 TR001414 United States TR NCATS NIH HHS; UG3 DK128298 United States DK NIDDK NIH HHS; RC1 DK086881 United States DK NIDDK NIH HHS; R01 DK030031 United States DK NIDDK NIH HHS; ZIA HD000641 United States ImNIH Intramural NIH HHS; R01 DK056781 United States DK NIDDK NIH HHS |
| فهرسة مساهمة: | Keywords: Homo sapiens; activity; basal metabolic rate; daily energy expenditure; energy compensation; energy management models; exercise; trade-offs; weight loss |
| تواريخ الأحداث: | Date Created: 20210828 Date Completed: 20220408 Latest Revision: 20240817 |
| رمز التحديث: | 20240817 |
| مُعرف محوري في PubMed: | PMC8551017 |
| DOI: | 10.1016/j.cub.2021.08.016 |
| PMID: | 34453886 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1879-0445 |
|---|---|
| DOI: | 10.1016/j.cub.2021.08.016 |