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Acute pancreatitis associated with multibacillary polychemotherapy for leprosy.

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العنوان: Acute pancreatitis associated with multibacillary polychemotherapy for leprosy.
المؤلفون: Maciel LG; Universidade Federal do Tocantins, Palmas, Tocantins, Brazil., França LAA; Universidade Federal do Tocantins, Palmas, Tocantins, Brazil., Deus BV; Universidade Federal do Tocantins, Palmas, Tocantins, Brazil., Formiga CCS; Universidade Federal do Tocantins, Palmas, Tocantins, Brazil.
المصدر: Revista do Instituto de Medicina Tropical de Sao Paulo [Rev Inst Med Trop Sao Paulo] 2021 Sep 27; Vol. 63, pp. e73. Date of Electronic Publication: 2021 Sep 27 (Print Publication: 2021).
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: Universidade de São Paulo, Instituto de Medicina Tropical de São Paulo Country of Publication: Brazil NLM ID: 7507484 Publication Model: eCollection Cited Medium: Internet ISSN: 1678-9946 (Electronic) Linking ISSN: 00364665 NLM ISO Abbreviation: Rev Inst Med Trop Sao Paulo Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Sao Paulo : Universidade de São Paulo, Instituto de Medicina Tropical de São Paulo
مواضيع طبية MeSH: Leprosy*/complications , Leprosy*/drug therapy , Leprosy, Multibacillary* , Pancreatitis*/chemically induced, Acute Disease ; Adult ; Drug Therapy, Combination ; Humans ; Leprostatic Agents/adverse effects ; Male
مستخلص: Acute pancreatitis (AP) is an inflammatory disease associated with abdominal pain and elevated serum pancreatic enzymes. The most common etiologies are gallstones and alcoholism. Drug-induced AP is quite rare, lacks a solid understanding and has been occasionally reported. The diagnosis requires a great suspicion and a careful exclusion of other causes. We present a case of a 37-year-old man, previously diagnosed with leprosy that developed acute pancreatitis after starting the multibacillary polychemotherapy (PCT/MB). After a month of treatment and the discontinuation of the PCT/MB, the therapy was restarted and a new episode of AP occurred. Three months after this last episode, the PCT/MB was reintroduced, changing one of the medications and the patient had no recurrence of AP or other reactions. Therefore, it is important to take into account that there is a risk of acute pancreatitis in patients on multidrug therapy (MDT) for leprosy.
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المشرفين على المادة: 0 (Leprostatic Agents)
تواريخ الأحداث: Date Created: 20210929 Date Completed: 20211001 Latest Revision: 20211015
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC8494489
DOI: 10.1590/S1678-9946202163073
PMID: 34586307
قاعدة البيانات: MEDLINE
الوصف
تدمد:1678-9946
DOI:10.1590/S1678-9946202163073