دورية أكاديمية
Small but mighty: Functional landscape of the versatile geminivirus-encoded C4 protein.
العنوان: | Small but mighty: Functional landscape of the versatile geminivirus-encoded C4 protein. |
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المؤلفون: | Medina-Puche L; Department of Plant Biochemistry, Centre for Plant Molecular Biology (ZMBP), Eberhard Karls University, Tübingen, Germany., Orílio AF; Dep. de Fitopatologia/BIOAGRO, Universidade Federal de Viçosa, Viçosa, Brazil.; National Research Institute for Plant-Pest Interactions, Universidade Federal de Viçosa, Viçosa, Brazil., Zerbini FM; Dep. de Fitopatologia/BIOAGRO, Universidade Federal de Viçosa, Viçosa, Brazil.; National Research Institute for Plant-Pest Interactions, Universidade Federal de Viçosa, Viçosa, Brazil., Lozano-Durán R; Department of Plant Biochemistry, Centre for Plant Molecular Biology (ZMBP), Eberhard Karls University, Tübingen, Germany.; Shanghai Center for Plant Stress Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, China. |
المصدر: | PLoS pathogens [PLoS Pathog] 2021 Oct 07; Vol. 17 (10), pp. e1009915. Date of Electronic Publication: 2021 Oct 07 (Print Publication: 2021). |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Review |
اللغة: | English |
بيانات الدورية: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: San Francisco, CA : Public Library of Science, c2005- |
مواضيع طبية MeSH: | Geminiviridae/*pathogenicity , Geminiviridae/*physiology , Viral Proteins/*metabolism, Evolution, Molecular ; Plant Diseases/genetics ; Virulence |
مستخلص: | The fast-paced evolution of viruses enables them to quickly adapt to the organisms they infect by constantly exploring the potential functional landscape of the proteins encoded in their genomes. Geminiviruses, DNA viruses infecting plants and causing devastating crop diseases worldwide, produce a limited number of multifunctional proteins that mediate the manipulation of the cellular environment to the virus' advantage. Among the proteins produced by the members of this family, C4, the smallest one described to date, is emerging as a powerful viral effector with unexpected versatility. C4 is the only geminiviral protein consistently subjected to positive selection and displays a number of dynamic subcellular localizations, interacting partners, and functions, which can vary between viral species. In this review, we aim to summarize our current knowledge on this remarkable viral protein, encompassing the different aspects of its multilayered diversity, and discuss what it can teach us about geminivirus evolution, invasion requirements, and virulence strategies. Competing Interests: The authors have declared that no competing interests exist. |
References: | Virology. 1994 Oct;204(1):82-90. (PMID: 8091687) Virus Res. 2012 Oct;169(1):107-16. (PMID: 22871297) J Exp Bot. 2018 Aug 14;69(18):4459-4468. (PMID: 29931348) New Phytol. 2021 Jul;231(2):747-762. (PMID: 33829507) EMBO J. 1986 Aug;5(8):1761-7. (PMID: 16453696) J Mol Evol. 1999 Nov;49(5):672-81. (PMID: 10552048) Arch Virol. 2008;153(7):1367-72. (PMID: 18521533) Mol Plant Microbe Interact. 2012 Oct;25(10):1294-306. (PMID: 22712505) Mol Ecol. 2021 Aug;30(15):3747-3767. (PMID: 34021651) J Virol. 2020 Sep 29;94(20):. (PMID: 32759325) J Gen Virol. 2013 Aug;94(Pt 8):1896-1907. (PMID: 23720217) Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):1388-1393. (PMID: 29363594) J Exp Bot. 2020 May 9;71(9):2817-2827. (PMID: 31990035) Arch Virol. 2016 Aug;161(8):2207-17. (PMID: 27231006) PLoS One. 2010 Jun 24;5(6):e11280. (PMID: 20585583) Viruses. 2018 Sep 11;10(9):. (PMID: 30208627) J Biol Chem. 2010 Apr 30;285(18):13471-9. (PMID: 20200150) J Virol. 2009 Mar;83(6):2697-707. (PMID: 19116260) Virology. 2018 Mar;516:1-20. (PMID: 29316505) Mol Plant Microbe Interact. 2007 Apr;20(4):380-91. (PMID: 17427808) Nat Commun. 2021 May 13;12(1):2780. (PMID: 33986276) PLoS Pathog. 2018 Aug 1;14(8):e1007207. (PMID: 30067843) Protein Sci. 1999 May;8(5):978-84. (PMID: 10338008) PLoS Pathog. 2018 Aug 29;14(8):e1007282. (PMID: 30157283) Plant Mol Biol. 2009 Sep;71(1-2):25-38. (PMID: 19533382) Front Microbiol. 2020 May 05;11:878. (PMID: 32431689) Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):. (PMID: 33723062) J Gen Virol. 2013 Feb;94(Pt 2):418-431. (PMID: 23136367) J Gen Virol. 1995 Jul;76 ( Pt 7):1773-80. (PMID: 9049382) Sci Rep. 2016 Jun 16;6:28249. (PMID: 27306108) J Gen Virol. 2017 Feb;98(2):131-133. (PMID: 28284245) J Virol. 2004 Sep;78(17):9487-98. (PMID: 15308741) PLoS One. 2015 Mar 27;10(3):e0122356. (PMID: 25815729) Mol Plant. 2018 Dec 3;11(12):1466-1481. (PMID: 30523782) New Phytol. 2020 Feb;225(3):1311-1326. (PMID: 31537050) PLoS Pathog. 2018 Jan 2;14(1):e1006789. (PMID: 29293689) Front Plant Sci. 2018 Jul 02;9:932. (PMID: 30013589) Planta. 2020 Sep 17;252(4):51. (PMID: 32940767) Arch Virol. 2015 Jun;160(6):1593-619. (PMID: 25894478) Nature. 1991 May 23;351(6324):320-2. (PMID: 2034276) J Virol. 2013 May;87(10):5397-413. (PMID: 23468482) PLoS Pathog. 2020 Oct 1;16(10):e1008829. (PMID: 33002088) Virology. 2001 Dec 5;291(1):110-25. (PMID: 11878881) Mol Plant Microbe Interact. 1996 Sep;9(7):594-9. (PMID: 8810074) Protoplasma. 2010 Mar;239(1-4):95-110. (PMID: 20091067) Nat Rev Microbiol. 2013 Nov;11(11):777-88. (PMID: 24100361) Front Plant Sci. 2017 Sep 27;8:1689. (PMID: 29021807) Virology. 1992 Sep;190(1):506-9. (PMID: 1529551) Virology. 2016 Nov;498:136-148. (PMID: 27584591) J Zhejiang Univ Sci B. 2014 Feb;15(2):133-42. (PMID: 24510706) Plant Cell. 2010 Feb;22(2):508-22. (PMID: 20179141) Sci Rep. 2021 May 27;11(1):11150. (PMID: 34045539) Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10381-6. (PMID: 16006510) Front Microbiol. 2020 May 05;11:851. (PMID: 32431688) Mol Plant Microbe Interact. 2011 Jul;24(7):849-61. (PMID: 21405986) PLoS One. 2011;6(5):e20054. (PMID: 21625602) J Gen Virol. 1991 May;72 ( Pt 5):1005-12. (PMID: 2033385) Plant J. 2009 Mar;57(5):905-17. (PMID: 19000158) Commun Biol. 2021 Apr 30;4(1):511. (PMID: 33931721) J Gen Virol. 2007 May;88(Pt 5):1624-1633. (PMID: 17412996) J Gen Virol. 2003 Mar;84(Pt 3):715-726. (PMID: 12604824) Viruses. 2019 Oct 31;11(11):. (PMID: 31683645) Virology. 2007 Jun 5;362(2):428-40. (PMID: 17280695) Virology. 1994 Nov 1;204(2):847-50. (PMID: 7941358) Science. 2002 Feb 15;295(5558):1299-301. (PMID: 11847343) Nucleic Acids Res. 1988 Jul 25;16(14B):7043-60. (PMID: 3405758) Cell. 2020 Sep 3;182(5):1109-1124.e25. (PMID: 32841601) Front Plant Sci. 2019 May 22;10:646. (PMID: 31191574) Mol Biol Evol. 2013 Aug;30(8):1916-28. (PMID: 23686658) Proc Biol Sci. 2013 Jun 26;280(1765):20130965. (PMID: 23804618) Annu Rev Phytopathol. 2013;51:357-81. (PMID: 23915133) BMC Plant Biol. 2019 May 2;19(1):173. (PMID: 31046667) |
المشرفين على المادة: | 0 (Viral Proteins) |
تواريخ الأحداث: | Date Created: 20211007 Date Completed: 20211126 Latest Revision: 20211126 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC8496806 |
DOI: | 10.1371/journal.ppat.1009915 |
PMID: | 34618877 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1553-7374 |
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DOI: | 10.1371/journal.ppat.1009915 |