دورية أكاديمية

Opioid Prescribing Patterns for Ulcerative Keratitis.

التفاصيل البيبلوغرافية
العنوان: Opioid Prescribing Patterns for Ulcerative Keratitis.
المؤلفون: Thibodeau AR; Department of Ophthalmology and Visual Sciences, W.K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI; and., Niziol LM; Department of Ophthalmology and Visual Sciences, W.K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI; and., Tannen BL; Department of Ophthalmology and Visual Sciences, W.K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI; and., Ballouz D; Department of Ophthalmology and Visual Sciences, W.K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI; and., Woodward MA; Department of Ophthalmology and Visual Sciences, W.K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI; and.; Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI.
المصدر: Cornea [Cornea] 2022 Apr 01; Vol. 41 (4), pp. 484-490.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8216186 Publication Model: Print Cited Medium: Internet ISSN: 1536-4798 (Electronic) Linking ISSN: 02773740 NLM ISO Abbreviation: Cornea Subsets: MEDLINE
أسماء مطبوعة: Publication: Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: New York, N.Y. : Masson Pub. USA, c1982-
مواضيع طبية MeSH: Analgesics, Opioid/*therapeutic use , Corneal Ulcer/*drug therapy , Drug Prescriptions/*statistics & numerical data , Eye Pain/*drug therapy , Practice Patterns, Physicians'/*statistics & numerical data, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Pain Management/methods ; Retrospective Studies
مستخلص: Purpose: The purpose of this study was to characterize rates of opioid prescription for different ulcerative keratitis types.
Methods: This cohort study included patients diagnosed with ulcerative keratitis according to the University of Michigan electronic health record data between September 1, 2014 and December 22, 2020. Ulcerative keratitis was categorized by etiologic type (bacterial, fungal, viral, acanthamoeba, inflammatory, polymicrobial, or unspecified) using rule-based data classification that accounted for billing diagnosis code, antimicrobial or antiinflammatory medications prescribed, laboratory results, and manual chart review. Opioid prescriptions were converted to morphine milligram equivalent and summed over 90 days from diagnosis. Opioid prescription rate and amount were compared between ulcerative keratitis types.
Results: Of 3322 patients with ulcerative keratitis, 173 (5.2%) were prescribed at least 1 opioid for pain management within 90 days of diagnosis. More patients with acanthamoeba (32.4%), fungal (21.1%), and polymicrobial (25.0%) keratitis were treated with opioids compared with bacterial (6.7%), unspecified (2.9%), or viral (1.8%) keratitis (all Bonferroni adjusted P < 0.05). For the 173 patients who were prescribed opioids, a total of 353 prescriptions were given within 90 days of diagnosis, with half given within the first week after diagnosis. The quantity of opioid prescribed within 90 days from diagnosis was not significantly different between ulcerative keratitis types (P = 0.6559). Morphine milligram equivalent units prescribed ranged from 97.5 for acanthamoeba keratitis to 112.5 for fungal keratitis.
Conclusions: The type of ulcerative keratitis may influence the opioid prescription rate. Providers can better serve patients needing opioids for pain management through improved characterization of pain and development of more tailored pain management regimens.
Competing Interests: The authors have no conflicts of interest to disclose.
(Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)
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معلومات مُعتمدة: R01 EY031033 United States EY NEI NIH HHS
المشرفين على المادة: 0 (Analgesics, Opioid)
تواريخ الأحداث: Date Created: 20211008 Date Completed: 20220311 Latest Revision: 20230402
رمز التحديث: 20230403
مُعرف محوري في PubMed: PMC8897229
DOI: 10.1097/ICO.0000000000002893
PMID: 34620771
قاعدة البيانات: MEDLINE
الوصف
تدمد:1536-4798
DOI:10.1097/ICO.0000000000002893