دورية أكاديمية
Epidemiological and clinical characteristics of patients with suspected COVID-19 admitted in Metro Manila, Philippines.
| العنوان: | Epidemiological and clinical characteristics of patients with suspected COVID-19 admitted in Metro Manila, Philippines. |
|---|---|
| المؤلفون: | Salva EP; San Lazaro Hospital, Manila, Philippines., Villarama JB; San Lazaro Hospital, Manila, Philippines., Lopez EB; San Lazaro Hospital, Manila, Philippines., Sayo AR; San Lazaro Hospital, Manila, Philippines., Villanueva AMG; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan., Edwards T; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.; MRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine, London, UK., Han SM; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.; Institute of Tropical Medicine, Nagasaki University, Nagasaki, 852-8523, Japan., Suzuki S; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan., Seposo X; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan., Ariyoshi K; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.; Institute of Tropical Medicine, Nagasaki University, Nagasaki, 852-8523, Japan., Smith C; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan. christopher.smith@lshtm.ac.uk.; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK. christopher.smith@lshtm.ac.uk. |
| المصدر: | Tropical medicine and health [Trop Med Health] 2020 Jun 22; Vol. 48 (1), pp. 51. Date of Electronic Publication: 2020 Jun 22. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: BioMed Central Ltd Country of Publication: Japan NLM ID: 101215093 Publication Model: Electronic Cited Medium: Print ISSN: 1348-8945 (Print) Linking ISSN: 13488945 NLM ISO Abbreviation: Trop Med Health Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Publication: <2016- > : London : BioMed Central Ltd. Original Publication: Nagasaki, Japan : Japanese Society of Tropical Medicine, [2004]- |
| مستخلص: | Background: Coronavirus disease 2019 (COVID-19) has spread to almost every region and country in the world, leading to widespread travel restrictions and national lockdowns. Currently, there are limited epidemiological and clinical data on COVID-19 patients from low and middle-income countries. We conducted a retrospective single-center study of the first 100 individuals with suspected COVID-19 (between Jan. 25 and Mar. 29, 2020) admitted to San Lazaro Hospital (SLH), the national infectious diseases referral hospital in Manila, Philippines. Results: Demographic data, travel history, clinical features, and outcomes were summarized and compared between COVID-19 confirmed and non-confirmed cases. The first two confirmed cases were Chinese nationals, admitted on Jan. 25. The third confirmed case was a Filipino, admitted on Mar. 8. Trends toward confirmed COVID-19 cases not reporting international travel and being admitted to SLH from the densely populated area of Manila city were observed during Mar. 8-29. All 42 of the 100 confirmed COVID-19 cases were adults, 40% were aged 60 years and above and 55% were male. Three were health workers. Among individuals with suspected COVID-19, confirmed cases were more likely to be older, Filipino, not report international travel history and have at least one underlying disease, particularly diabetes, report difficulty in breathing, and a longer duration of symptoms. In over 90% of non-COVID-19 cases, the alternative diagnosis was respiratory. Nine (21%) confirmed cases died. The median duration from symptoms onset to death was 11.5 (range: 8-18) days. Conclusions: Imported COVID-19 cases have reduced but local transmission persists and there is a trend toward cases being admitted to SLH from densely populated areas. This study highlights the difficulty in diagnosing COVID-19 on clinical grounds and the importance of diagnostic capacity in all settings. Difficulty of breathing was the only symptom associated with COVID-19 infection and should alert clinicians to the possibility of COVID-19. Clinical characteristics of confirmed COVID-19 cases and a hospital case fatality rate of 21% are comparable with other settings. (© 2021. The Author(s).) |
| التعليقات: | Erratum in: Trop Med Health. 2020 Jul 7;48:56. (PMID: 32647491) Erratum in: Trop Med Health. 2021 Oct 22;49(1):85. (PMID: 34686214) |
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| فهرسة مساهمة: | Keywords: COVID-19; Case fatality rate; Coronavirus; Epidemiology; Manila; Philippines; SARS-CoV-2 |
| تواريخ الأحداث: | Date Created: 20211023 Latest Revision: 20230328 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC7306563 |
| DOI: | 10.1186/s41182-020-00241-8 |
| PMID: | 34686216 |
| قاعدة البيانات: | MEDLINE |
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