دورية أكاديمية
Indicuen, a new hopane from Parmotrema indicum Hale growing in Vietnam.
| العنوان: | Indicuen, a new hopane from Parmotrema indicum Hale growing in Vietnam. |
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| المؤلفون: | Nguyen TQ; Faculty of Environmental Science, Sai Gon University, Ho Chi Minh City, Vietnam., Pham NK; Faculty of Environmental Science, Sai Gon University, Ho Chi Minh City, Vietnam., Trung NT; Laboratory of Computational Chemistry and Modelling (LCCM), Quy Nhon University, Quy Nhon, Vietnam., An NT; Laboratory of Computational Chemistry and Modelling (LCCM), Quy Nhon University, Quy Nhon, Vietnam., Mai DT; Graduate University of Science and Technology, Vietnam Academy of Science and Technology, Ha Noi, Vietnam.; Institute of Chemical Technology, Vietnam Academy of Science and Technology, Ho Chi Minh City, Vietnam., Sichaem J; Research Unit in Natural Products Chemistry and Bioactivities, Faculty of Science and Technology, Thammasat University Lampang Campus, Lampang, Thailand., Huynh BL; Department of Nature, Dong Nai University, Biên Hòa, Dong Nai, Vietnam., Anh NTH; Ho Chi Minh City University of Food Industry, 140 Le Trong Tan Street, Tay Thanh Ward, Tan Phu District, HCMC, Vietnam., Nguyen NH; CirTech Institute, Ho Chi Minh City University of Technology (HUTECH), Ho Chi Minh City, Vietnam., Duong TH; Department of Chemistry, University of Education, Ho Chi Minh City, Vietnam. |
| المصدر: | Natural product research [Nat Prod Res] 2023 Apr; Vol. 37 (8), pp. 1284-1291. Date of Electronic Publication: 2021 Nov 10. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Milton Park, UK : Taylor & Francis Health Sciences, c2003- |
| مواضيع طبية MeSH: | Parmeliaceae* , Lichens*/chemistry , Triterpenes*/pharmacology, Molecular Structure ; Vietnam ; alpha-Glucosidases ; Pentacyclic Triterpenes |
| مستخلص: | One new hopane-type triterpene, indicuen ( 1 ), along with eight known compounds ( 2-9 ) were isolated from the n -hexane extract of the lichen Parmotrema indicum Hale. The chemical structures of isolated compounds were identified by interpretation of their spectroscopic data (1D, 2D NMR and HRESIMS) combined with DFT-NMR chemical shift calculations and subsequent assignment of DP4+ probabilities and by comparison with the literature. Indicuen represents for a rare hopane bearing a 1-carboxyethyl substituent at C-21 in lichens. Compounds 1-3 and 5 - 8 were evaluated for α -glucosidase inhibition and cytotoxicity against K562 and HepG2 cancer cell lines. Compounds 1 , 5 and 7 exhibited moderate α -glucosidase inhibition with IC |
| فهرسة مساهمة: | Keywords: Lichen; Parmotrema indicum Hale; cytotoxicity; indicuen; triterpene; α-glucosidase inhibition |
| المشرفين على المادة: | EC 3.2.1.20 (alpha-Glucosidases) 0 (Triterpenes) 0 (Pentacyclic Triterpenes) |
| تواريخ الأحداث: | Date Created: 20211111 Date Completed: 20230321 Latest Revision: 20230321 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1080/14786419.2021.2003355 |
| PMID: | 34758682 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1478-6427 |
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| DOI: | 10.1080/14786419.2021.2003355 |