دورية أكاديمية
Predicting the Exception-CRP and Primary Hip Arthroplasty.
| العنوان: | Predicting the Exception-CRP and Primary Hip Arthroplasty. |
|---|---|
| المؤلفون: | Meier MP; Department of Trauma, Orthopedics and Reconstructive Surgery, Georg-August-University of Goettingen, 37075 Göttingen, Germany., Bauer IJ; Department of Trauma, Orthopedics and Reconstructive Surgery, Georg-August-University of Goettingen, 37075 Göttingen, Germany., Maheshwari AK; Kogod Center on Aging and Division of Endocrinology, Mayo Clinic, Rochester, MN 55905, USA., Husen M; Department of Orthopedic Surgery, Rochester, MN 55905, USA.; Department of Trauma, Hand and Reconstructive Surgery, University Hospital Essen, 45147 Essen, Germany., Jäckle K; Department of Trauma, Orthopedics and Reconstructive Surgery, Georg-August-University of Goettingen, 37075 Göttingen, Germany., Hubert J; Division of Orthopaedics, Department of Trauma and Orthopaedic Surgery, University Medical Center Hamburg-Eppendorf, 20521 Hamburg, Germany., Hawellek T; Department of Trauma, Orthopedics and Reconstructive Surgery, Georg-August-University of Goettingen, 37075 Göttingen, Germany., Lehmann W; Department of Trauma, Orthopedics and Reconstructive Surgery, Georg-August-University of Goettingen, 37075 Göttingen, Germany., Saul D; Department of Trauma, Orthopedics and Reconstructive Surgery, Georg-August-University of Goettingen, 37075 Göttingen, Germany.; Kogod Center on Aging and Division of Endocrinology, Mayo Clinic, Rochester, MN 55905, USA. |
| المصدر: | Journal of clinical medicine [J Clin Med] 2021 Oct 27; Vol. 10 (21). Date of Electronic Publication: 2021 Oct 27. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101606588 Publication Model: Electronic Cited Medium: Print ISSN: 2077-0383 (Print) Linking ISSN: 20770383 NLM ISO Abbreviation: J Clin Med Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI AG, [2012]- |
| مستخلص: | Background: While primary hip arthroplasty is the most common operative procedure in orthopedic surgery, a periprosthetic joint infection is its most severe complication. Early detection and prediction are crucial. In this study, we aimed to determine the value of postoperative C-reactive protein (CRP) and develop a formula to predict this rare, but devastating complication. Methods: We retrospectively evaluated 708 patients with primary hip arthroplasty. CRP, white blood cell count (WBC), and several patient characteristics were assessed for 20 days following the operative procedure. Results: Eight patients suffered an early acute periprosthetic infection. The maximum CRP predicted an infection with a sensitivity and specificity of 75% and 56.9%, respectively, while a binary logistic regression reached values of 75% and 80%. A multinominal logistic regression, however, was able to predict an early infection with a sensitivity and specificity of 87.5% and 78.9%. With a one-phase decay, 71.6% of the postoperative CRP-variance could be predicted. Conclusion: To predict early acute periprosthetic joint infection after primary hip arthroplasty, a multinominal logistic regression is the most promising approach. Including five parameters, an early infection can be predicted on day 5 after the operative procedure with 87.5% sensitivity, while it can be excluded with 78.9% specificity. |
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| معلومات مُعتمدة: | 413501650 Deutsche Forschungsgemeinschaft; 466023693 Deutsche Forschungsgemeinschaft |
| فهرسة مساهمة: | Keywords: C-reactive protein; CRP; orthopedic surgery; periprosthetic joint infection; primary hip arthroplasty; revision surgery |
| تواريخ الأحداث: | Date Created: 20211113 Latest Revision: 20240404 |
| رمز التحديث: | 20240404 |
| مُعرف محوري في PubMed: | PMC8584609 |
| DOI: | 10.3390/jcm10214985 |
| PMID: | 34768504 |
| قاعدة البيانات: | MEDLINE |
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