دورية أكاديمية
Multi-site comparison of factors influencing progress of African insecticide testing facilities towards an international Quality Management System certification.
| العنوان: | Multi-site comparison of factors influencing progress of African insecticide testing facilities towards an international Quality Management System certification. |
|---|---|
| المؤلفون: | Begg S; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom., Wright A; London School of Hygiene and Tropical Medicine, Keppel St, Bloomsbury, London, United Kingdom., Small G; Innovative Vector Control Consortium, Pembroke Place, Liverpool, United Kingdom., Kirby M; London School of Hygiene and Tropical Medicine, Keppel St, Bloomsbury, London, United Kingdom.; KCMUCo-PAMVERC, KCMUCo-PAMVERC Test Facility, Moshi, Tanzania., Moore S; Ifakara Health Institute, Off Mlabani Passage, Ifakara, Tanzania., Koudou B; Centre Suisse de Recherches Scientifques en Côte D'Ivoire, Route de Dabou, Abidjan, Côte d'Ivoire., Kisinza W; National Institute of Medical Research, Amani Centre, Amani Medical Research Centre, Muheza, Tanzania., Abdoulaye D; Institut de Recherche en Sciences de la Santé, Bobo-Dioulasso, Bobo-Dioulasso, Burkina Faso, Côte d'Ivoire., Moore J; Ifakara Health Institute, Off Mlabani Passage, Ifakara, Tanzania., Malima R; National Institute of Medical Research, Amani Centre, Amani Medical Research Centre, Muheza, Tanzania., Kija P; National Institute of Medical Research, Amani Centre, Amani Medical Research Centre, Muheza, Tanzania., Mosha F; KCMUCo-PAMVERC, KCMUCo-PAMVERC Test Facility, Moshi, Tanzania., Edi C; Centre Suisse de Recherches Scientifques en Côte D'Ivoire, Route de Dabou, Abidjan, Côte d'Ivoire., Bates I; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom. |
| المصدر: | PloS one [PLoS One] 2021 Nov 15; Vol. 16 (11), pp. e0259849. Date of Electronic Publication: 2021 Nov 15 (Print Publication: 2021). |
| نوع المنشور: | Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: San Francisco, CA : Public Library of Science |
| مواضيع طبية MeSH: | Certification/*organization & administration , Health Facilities/*standards , Insecticides/*pharmacology, Africa South of the Sahara ; Financial Support ; Humans ; World Health Organization |
| مستخلص: | Background: Insecticidal mosquito vector control products are vital components of malaria control programmes. Test facilities are key in assessing the effectiveness of vector control products against local mosquito populations, in environments where they will be used. Data from these test facilities must be of a high quality to be accepted by regulatory authorities, including the WHO Prequalification Team for vector control products. In 2013-4, seven insecticide testing facilities across sub-Saharan Africa, with technical and financial support from Innovative Vector Control Consortium (IVCC), began development and implementation of quality management system compliant with the principles of Good Laboratory Practice (GLP) to improve data quality and reliability. Methods and Principle Findings: We conducted semi-structured interviews, emails, and video-call interviews with individuals at five test facilities engaged in the IVCC-supported programme and working towards or having achieved GLP. We used framework analysis to identify and describe factors affeting progress towards GLP. We found that eight factors were instrumental in progress, and that test facilities had varying levels of control over these factors. They had high control over the training programme, project planning, and senior leadership support; medium control over infrastructure development, staff structure, and procurement; and low control over funding the availability and accessibility of relevant expertise. Collaboration with IVCC and other partners was key to overcoming the challenges associated with low and medium control factors. Conclusion: For partnership and consortia models of research capacity strengthening, test facilities can use their own internal resources to address identified high-control factors. Project plans should allow additional time for interaction with external agencies to address medium-control factors, and partners with access to expertise and funding should concentrate their efforts on supporting institutions to address low-control factors. In practice, this includes planning for financial sustainability at the outset, and acting to strengthen national and regional training capacity. Competing Interests: The authors have declared that no competing interests exist. |
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| المشرفين على المادة: | 0 (Insecticides) |
| تواريخ الأحداث: | Date Created: 20211115 Date Completed: 20211229 Latest Revision: 20240612 |
| رمز التحديث: | 20240612 |
| مُعرف محوري في PubMed: | PMC8592480 |
| DOI: | 10.1371/journal.pone.0259849 |
| PMID: | 34780512 |
| قاعدة البيانات: | MEDLINE |
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