دورية أكاديمية

Dietary calcium to phosphorus ratio affects postprandial phosphorus concentrations in feline plasma.

التفاصيل البيبلوغرافية
العنوان: Dietary calcium to phosphorus ratio affects postprandial phosphorus concentrations in feline plasma.
المؤلفون: Coltherd JC; Waltham Petcare Science Institute, Waltham-on-the-Wolds, Leicestershire, UK., Staunton R; Waltham Petcare Science Institute, Waltham-on-the-Wolds, Leicestershire, UK., Colyer A; Waltham Petcare Science Institute, Waltham-on-the-Wolds, Leicestershire, UK., Gilham M; Waltham Petcare Science Institute, Waltham-on-the-Wolds, Leicestershire, UK., Rawlings J; Waltham Petcare Science Institute, Waltham-on-the-Wolds, Leicestershire, UK., Alexander JE; Waltham Petcare Science Institute, Waltham-on-the-Wolds, Leicestershire, UK., Logan DW; Waltham Petcare Science Institute, Waltham-on-the-Wolds, Leicestershire, UK., Butterwick R; Waltham Petcare Science Institute, Waltham-on-the-Wolds, Leicestershire, UK., Watson P; Waltham Petcare Science Institute, Waltham-on-the-Wolds, Leicestershire, UK., Bakke AM; Waltham Petcare Science Institute, Waltham-on-the-Wolds, Leicestershire, UK.
المصدر: The British journal of nutrition [Br J Nutr] 2022 Nov 14; Vol. 128 (9), pp. 1689-1699. Date of Electronic Publication: 2021 Nov 18.
نوع المنشور: Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Published on behalf of the Nutrition Society by CABI Publishing Country of Publication: England NLM ID: 0372547 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-2662 (Electronic) Linking ISSN: 00071145 NLM ISO Abbreviation: Br J Nutr Subsets: MEDLINE
أسماء مطبوعة: Publication: <2000->: Wallingford, Oxon, UK : Published on behalf of the Nutrition Society by CABI Publishing
Original Publication: [Cambridge, New York] Cambridge University Press.
مواضيع طبية MeSH: Calcium, Dietary*/metabolism , Phosphorus, Dietary*, Adult ; Cats ; Animals ; Humans ; Phosphorus ; Parathyroid Hormone ; Diet/veterinary ; Calcium
مستخلص: The impact of dietary phosphorus on chronic renal disease in cats, humans and other species is receiving increasing attention. As Ca and P metabolism are linked, the ratio of Ca:P is an important factor for consideration when formulating diets for cats and other animals. Here, we describe a fully randomised crossover study including twenty-four healthy, neutered adult cats, investigating postprandial responses in plasma P, ionised Ca and parathyroid hormone (PTH) following one meal (50 % of individual metabolic energy requirement) of each of six experimental diets. Diets were formulated to provide P at either 0·75 or 1·5 g/1000 kcal (4184 kJ) from the soluble phosphorus salt sodium tripolyphosphate (STPP, Na 5 P 3 O 10 ), variable levels of organic Ca and P sources, and an intended total Ca:P of about 1·0, 1·5 or 2·0. For each experimental diet, baseline fasted blood samples were collected prior to the meal, and serial blood samples collected hourly for 6 h thereafter. For all diets, a significant increase from baseline was observed at 120 min in plasma PTH ( P < 0·001). The diet containing the highest STPP inclusion level and lowest Ca:P induced the highest peaks in postprandial plasma P and PTH levels (1·8 mmol/l and 27·2 pg/ml, respectively), and the longest duration of concentrations raised above baseline were observed at 3 h for P and 6 h for PTH. Data indicate that Ca:P modulates postprandial plasma P and PTH. Therefore, when formulating diets containing soluble P salts for cats, increasing the Ca:P ratio should be considered.
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فهرسة مساهمة: Keywords: Cats; PTH; Plasma phosphorus kinetics
المشرفين على المادة: 0 (Calcium, Dietary)
27YLU75U4W (Phosphorus)
0 (Parathyroid Hormone)
0 (Phosphorus, Dietary)
SY7Q814VUP (Calcium)
تواريخ الأحداث: Date Created: 20211118 Date Completed: 20221221 Latest Revision: 20240906
رمز التحديث: 20240906
مُعرف محوري في PubMed: PMC9592954
DOI: 10.1017/S000711452100461X
PMID: 34789346
قاعدة البيانات: MEDLINE
الوصف
تدمد:1475-2662
DOI:10.1017/S000711452100461X