دورية أكاديمية
Effect of anaerobic resistance training on gastric emptying of solids, nutritional parameters and food behavior in the rats treated with dexamethasone.
| العنوان: | Effect of anaerobic resistance training on gastric emptying of solids, nutritional parameters and food behavior in the rats treated with dexamethasone. |
|---|---|
| المؤلفون: | Telles PVN; Postgraduate Program in Pharmacology, Federal University of Piauí, Teresina-PI, Brazil; Laboratory of Exercise and Gastrointestinal Tract - Department of Physical Education, Federal University of Piauí, Teresina-PI, Brazil., Severo JS; Postgraduate Program in Food and Nutrition, Federal University of Piauí, Teresina-PI, Brazil., de Oliveira LCS; Postgraduate Program in Food and Nutrition, Federal University of Piauí, Teresina-PI, Brazil., Reis E Sousa JF; Laboratory of Exercise and Gastrointestinal Tract - Department of Physical Education, Federal University of Piauí, Teresina-PI, Brazil., Cavalcante AKM; Department of Physiology and Pharmacology, School of Medicine, Federal University of Ceará, Fortaleza-CE, Brazil., da Silva ACA; Postgraduate Program in Pharmacology, Federal University of Piauí, Teresina-PI, Brazil., Aguiar Dos Santos A; Department of Physiology and Pharmacology, School of Medicine, Federal University of Ceará, Fortaleza-CE, Brazil., Tolentino Bento da Silva M; Postgraduate Program in Pharmacology, Federal University of Piauí, Teresina-PI, Brazil; Postgraduate Program in Food and Nutrition, Federal University of Piauí, Teresina-PI, Brazil; Laboratory of Exercise and Gastrointestinal Tract - Department of Physical Education, Federal University of Piauí, Teresina-PI, Brazil. Electronic address: tolentino@ufpi.edu.br. |
| المصدر: | Physiology & behavior [Physiol Behav] 2022 Mar 01; Vol. 245, pp. 113674. Date of Electronic Publication: 2021 Dec 16. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Country of Publication: United States NLM ID: 0151504 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-507X (Electronic) Linking ISSN: 00319384 NLM ISO Abbreviation: Physiol Behav Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York NY : Elsevier Science Original Publication: Oxford, Eng., Long Island City, Pergamon Press. |
| مواضيع طبية MeSH: | Gastric Emptying*/physiology , Resistance Training*, Anaerobiosis ; Animals ; Dexamethasone/pharmacology ; Humans ; Rats ; Rats, Wistar |
| مستخلص: | Dexamethasone (Dexa) is a potent glucocorticoid that can trigger side effects, such as neuromuscular, cardiovascular, and gastric motility disorders. Exercise can ameliorate gastrointestinal disorders. However, it is not clear whether exercise can modulate the side effects of using Dexa on gastric motility. To investigate the role of anaerobic resistance training (ART) on gastric motility and feeding behavior of rats treated with dexamethasone, rats were divided into three groups: control (Ctrl), dexamethasone (Dexa), and anaerobic resistance training + dexamethasone (ARTDexa). Anaerobic resistance training (ART) consisted of climbing a vertical ladder 5 days/week (with intensity of 50% to 100% of the maximum overload/8 weeks). At the end of the ART or control period, the rats received Dexa (1 mg/kg i.p) for 10 consecutive days. In the end, we evaluated anthropometric parameters and feeding behavior, heart rate, gastric emptying, and lipid profile in all groups. We observed significant decrease (p < 0.05) in body weight and food intake in the Dexa and ARTDexa groups compared to the control. Dexa promoted significant tachycardia (p < 0.05) and a decrease (p < 0.05) in the r-r' interval. The ART significantly prevented (p < 0.05) cardiovascular effects. Dexa induced a decrease (p < 0.05) in gastric emptying compared to the control group. On the other hand, ART significantly prevented (p < 0.05) the decrease in gastric emptying compared to Dexa. The chronic use of Dexa caused tachycardia, decreased food intake, and decreased gastric emptying. The ART modulated cardiovascular parameters, improving tachycardia. In addition, this exercise prevented gastric dysmotility induced by dexamethasone. (Copyright © 2021 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Dexamethasone; Food Behavior; Gastric Emptying; Resistance exercise |
| المشرفين على المادة: | 7S5I7G3JQL (Dexamethasone) |
| تواريخ الأحداث: | Date Created: 20211218 Date Completed: 20220411 Latest Revision: 20240112 |
| رمز التحديث: | 20240112 |
| DOI: | 10.1016/j.physbeh.2021.113674 |
| PMID: | 34921837 |
| قاعدة البيانات: | MEDLINE |
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