تقرير
Clinical and aetiologic profile of patients with chronic urticaria at the outpatient clinic of a tertiary hospital in Lagos, Nigeria: a cross-sectional observational study.
| العنوان: | Clinical and aetiologic profile of patients with chronic urticaria at the outpatient clinic of a tertiary hospital in Lagos, Nigeria: a cross-sectional observational study. |
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| المؤلفون: | Gold-Olufadi S; University College Hospital, Oyo State, Ibadan, Nigeria., Ayanlowo O; University of Lagos, Lagos University Teaching Hospital, Lagos, Nigeria., Akinkugbe AO; University of Lagos, Lagos University Teaching Hospital, Lagos, Nigeria., Otrofanowei E; University of Lagos, Lagos University Teaching Hospital, Lagos, Nigeria. |
| المصدر: | The Pan African medical journal [Pan Afr Med J] 2021 Nov 05; Vol. 40, pp. 141. Date of Electronic Publication: 2021 Nov 05 (Print Publication: 2021). |
| نوع المنشور: | Case Reports; Observational Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: African Field Epidemiology Network Country of Publication: Uganda NLM ID: 101517926 Publication Model: eCollection Cited Medium: Internet ISSN: 1937-8688 (Electronic) NLM ISO Abbreviation: Pan Afr Med J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Kampala, Uganda : African Field Epidemiology Network |
| مواضيع طبية MeSH: | Chronic Urticaria* , Urticaria*/epidemiology , Urticaria*/etiology, Ambulatory Care Facilities ; Female ; Humans ; Nigeria/epidemiology ; Tertiary Care Centers |
| مستخلص: | Chronic urticaria is a condition characterized by recurrent wheals associated with itching lasting longer than six weeks. The condition tends to run a chronic course with significant morbidity. Several factors have been explored in the cause, yet the aetiology is still uncertain. We documented the clinical profile and assessed the possible aetiologic factors in patients with chronic urticaria. Clinical profile of sixty consecutive patients with chronic spontaneous urticaria was assessed with possible precipitants identified using a structured questionnaire. The complete blood count with erythrocyte sedimentation rate, antithyroid peroxidase (antiTPO), hepatitis B surface antigen (HBsAg), antihepatitis C virus screening (AntiHCV), stool for ova and parasites and helicobacter pylori were carried out. Controls without a history of urticaria were recruited in a 1: 1 ratio for stool for parasites and H. pylori because of the high prevalence rates reported in this environment. Data analysis was carried out with Statistical Packages for Social Sciences (SPSS) version 22. Sixty patients with chronic urticaria and sixty age and sex matched controls were enrolled in the study. Females presented more often with urticaria with a M: F ratio of 1: 2.5. The mean age of onset of urticaria was in the third decade of life. Precipitants were identified in close to a third of patients. The investigated antigenic aetiology was not found to play a role. The presentation and clinical profile of patients in this environment is similar to previously documented studies. History still remains the cornerstone of management as precipitants and triggers may be identified. Management of patients should therefore be individualized. Competing Interests: The authors declare no competing interests. (Copyright: Shakirat Gold-Olufadi et al.) |
| References: | Ann Allergy Asthma Immunol. 2002 Aug;89(2):195-6. (PMID: 12197577) J Investig Allergol Clin Immunol. 2004;14(3):214-20. (PMID: 15552715) Drugs. 2004;64(22):2515-36. (PMID: 15516152) J Dermatol. 2007 May;34(5):294-301. (PMID: 17408437) J Investig Allergol Clin Immunol. 2009;19 Suppl 2:21-6. (PMID: 19530414) Niger J Clin Pract. 2015 Mar-Apr;18(2):163-72. (PMID: 25665986) J Am Acad Dermatol. 2001 Sep;45(3):387-91. (PMID: 11511835) Allergy. 2018 Jul;73(7):1393-1414. (PMID: 29336054) Allergy. 2010 Jan;65(1):78-83. (PMID: 19796222) Allergy Asthma Immunol Res. 2014 Jan;6(1):13-21. (PMID: 24404388) J Allergy Clin Immunol. 2002 Sep;110(3):492-9. (PMID: 12209101) Allergy. 2004 Aug;59(8):869-73. (PMID: 15230821) Allergy. 2009 Oct;64(10):1417-1426. (PMID: 19772512) Allergy. 1997 May;52(5):504-13. (PMID: 9201361) Clin Exp Allergy. 2007 May;37(5):631-50. (PMID: 17456211) |
| فهرسة مساهمة: | Keywords: Chronic urticaria; aetiology; precipitants |
| تواريخ الأحداث: | Date Created: 20211220 Date Completed: 20211221 Latest Revision: 20211221 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC8654876 |
| DOI: | 10.11604/pamj.2021.40.141.27655 |
| PMID: | 34925676 |
| قاعدة البيانات: | MEDLINE |
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